Results 41 to 50 of about 2,359,106 (231)

Prevalence of colistin resistance of Klebsiella pneumoniae isolates in Iran: a systematic review and meta-analysis

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2022
Objective Klebsiella pneumoniae is a gram-negative pathogen common cause of nosocomial infections. Colistin is a last resort antibiotic to treat infections caused by K. pneumoniae.
Negar Narimisa   +2 more
doaj   +1 more source

Investigation of Colistin Heteroresistance and Some Factors Affecting Heteroresistance in Carbapenem-Resistant A. baumannii Strains [PDF]

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2017
Introduction: Colistin can be used in patients infected with carbapenem-resistant Acinetobacter baumannii complex (CR-ABC), but recently resistance to colistin and heteroresistance have been reported.
Deniz GAZEL, Müşerref TATMAN OTKUN
doaj   +1 more source

Evaluation of Plasmid Mediated Colistin Resistance in Colistin Resistant Gram-negative Bacilli

open access: yesJournal of Kermanshah University of Medical Sciences, 2023
Background: Infections caused by carbapenem-resistant gram-negative bacteria are treated with colonistin as a last resort. However, the increased resistance in recent years is significant for treating multiple drug-resistant infections. Objectives: This study aimed to determine the resistance genes mobile colistin resistance (mcr)-1 and mcr-2 in the ...
Yeliz Tanriverdi Cayci   +4 more
openaire   +1 more source

Colistin Resistance in Environmental Isolates of Acinetobacter baumannii

open access: yes, 2020
Although the molecular mechanisms of carbapenem resistance of environmental isolates ofAcinetobacter baumanniiare well described, data on the mechanisms of colistin resistance are scarce.
Jovčić, Branko   +3 more
core   +1 more source

Deciphering MCR-2 Colistin Resistance [PDF]

open access: yesmBio, 2017
ABSTRACT Antibiotic resistance is a prevalent problem in public health worldwide. In general, the carbapenem β-lactam antibiotics are considered a final resort against lethal infections by multidrug-resistant bacteria. Colistin is a cationic polypeptide antibiotic and acts as the last line of defense for treatment of carbapenem ...
Jian Sun   +11 more
openaire   +3 more sources

Colistin: A mainstay antibiotic for treatment of fatal Gram negative bacterial infections [PDF]

open access: yesERU Research Journal
Our world is facing an enormous disaster due to spreading of the life-threatening bacterial infections, especially after the spread of multidrug-resistant Gram-negative bacteria (MDR-GNB), including those resistant to known antibiotics such as ...
Ahmed El-Khatib, Ahmed Basyony
doaj   +1 more source

First report of plasmid-mediated colistin resistance mcr-8.1 gene from a clinical Klebsiella pneumoniae isolate from Lebanon [PDF]

open access: yes, 2020
Colistin is considered as a last resort treatment for infections caused by multidrug-resistant Enterobacteriaceae. Plasmid-mediated mobile colistin resistance (mcr) genes contributed to the global spread of colistin resistance.
Salloum, Tamara   +5 more
core   +1 more source

Acinetobacter baumannii under Acidic Conditions Induces Colistin Resistance through PmrAB Activation and Lipid A Modification

open access: yes, 2023
Colistin is a last-resort antimicrobial agent for treating carbapenem-resistant Acinetobacter baumannii infections. The activation of PmrAB by several environmental signals induces colistin resistance in Gram-negative bacteria.
Minsang Shin   +5 more
core   +1 more source

Emergence of colistin resistance in the largest university hospital complex of São Paulo, Brazil, over five years

open access: yesBrazilian Journal of Infectious Diseases, 2017
Colistin resistance involving Gram-negative bacilli infections is a challenge for health institutions around of the world. Carbapenem-resistance among these isolates makes colistin the last therapeutic option for this treatment. Colistin resistance among
Flávia Rossi   +5 more
doaj   +1 more source

Detection of Plasmid-Mediated Resistance against Colistin in Multi-Drug-Resistant Gram-Negative Bacilli Isolated from a Tertiary Hospital

open access: yes, 2023
The aim of this study was to determine the prevalence of plasmid-mediated colistin resistance mcr-1 to mcr-5 genes among colistin and multi-drug-resistant Gram-negative bacilli strains isolated from patients in a tertiary hospital in Toluca, Mexico.
Laura Guadarrama-Monroy   +6 more
core   +1 more source

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