Results 41 to 50 of about 2,218,812 (219)

Prevalence and transmission risk of colistin and multidrug resistance in long-distance coastal aquaculture

, 2023
Due to the wide use of antibiotics, intensive aquaculture farms have been recognized as a significant reservoir of antibiotic resistomes. Although the prevalence of colistin resistance genes and multidrug-resistant bacteria (MDRB) has been documented ...
Zhao, Huijun, An, Taicheng, Wong, Po Keung, Cai, Yiwei, Li, Shaoting, Guo, Jianhua, Li, Guiying   +6 more
core   +1 more source

Characterisation of mcr-4.3 in a colistin-resistant Acinetobacter nosocomialis clinical isolate from Cape Town, South Africa

Journal of Global Antimicrobial Resistance, 2021
: Objectives: Colistin resistance in Acinetobacter spp. is increasing, resulting in potentially untreatable nosocomial infections. Plasmid-mediated colistin resistance is of particular concern due to its low fitness cost and potential transferability to
Yolandi Snyman, Sandra Reuter, Andrew Christopher Whitelaw, Lisa Stein, Motlatji Reratilwe Bonnie Maloba, Mae Newton-Foot   +5 more
doaj   +1 more source

Colistin-phage combinations decrease antibiotic resistance in Acinetobacter baumannii via changes in envelope architecture

, 2021
Multidrug-resistant bacterial infections are becoming increasingly common, with only few last-resort antibiotics such as colistin available for clinical therapy.
Xiaoting Hua (435699), Xiaoqing Wang (514179), Belinda Loh (3596981), Yunsong Yu (496103), Fernando Gordillo Altamirano (11792613), Sebastian Leptihn (2189809)   +5 more
core   +1 more source

Colistin Resistance among Enterobacterales Isolates: Underlying Mechanisms and Alternative Treatment Options

Journal of Pure and Applied Microbiology, 2023
Global dissemination of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria (GNB) such as carbapenemase-producing Enterobacterales has resulted in reviving colistin as a final therapeutic alternative. Colistin resistance
Amal F. Makled, Sahar A.M. Ali, Ahmed B. Mahmoud, Marwa E. Eltoukhy, Reem M. Elkholy, Athar F. Lasheen, Asmaa Mohammed Elbrolosy   +6 more
doaj   +1 more source

Prevalence of colistin resistance of Klebsiella pneumoniae isolates in Iran: a systematic review and meta-analysis

Annals of Clinical Microbiology and Antimicrobials, 2022
Objective Klebsiella pneumoniae is a gram-negative pathogen common cause of nosocomial infections. Colistin is a last resort antibiotic to treat infections caused by K. pneumoniae.
Negar Narimisa, Forough Goodarzi, Shirin Bavari   +2 more
doaj   +1 more source

New Mutations Involved in Colistin Resistance in Acinetobacter baumannii

mSphere, 2020
Colistin is used as the “last resort” to treat infections caused by multidrug-resistant Acinetobacter baumannii, which is at the top of the World Health Organization’s list of the most dangerous bacterial species that threaten human health. Unfortunately,
Bingbing Sun, Haiyan Liu, Yu Jiang, Lei Shao, Sheng Yang, Daijie Chen   +5 more
doaj   +1 more source

Investigation of Colistin Heteroresistance and Some Factors Affecting Heteroresistance in Carbapenem-Resistant A. baumannii Strains [PDF]

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2017
Introduction: Colistin can be used in patients infected with carbapenem-resistant Acinetobacter baumannii complex (CR-ABC), but recently resistance to colistin and heteroresistance have been reported.
Deniz GAZEL, Müşerref TATMAN OTKUN
doaj   +1 more source

Plasmid-mediated mcr-1 colistin resistance in Escherichia coli and Klebsiella spp. clinical isolates from the Western Cape region of South Africa

Antimicrobial Resistance and Infection Control, 2017
Background Colistin is a last resort antibiotic for the treatment of carbapenem-resistant Gram negative infections. Until recently, mechanisms of colistin resistance were limited to chromosomal mutations which confer a high fitness cost and cannot be ...
Mae Newton-Foot, Yolandi Snyman, Motlatji Reratilwe Bonnie Maloba, Andrew Christopher Whitelaw   +3 more
doaj   +1 more source

First report of plasmid-mediated colistin resistance mcr-8.1 gene from a clinical Klebsiella pneumoniae isolate from Lebanon [PDF]

, 2020
Colistin is considered as a last resort treatment for infections caused by multidrug-resistant Enterobacteriaceae. Plasmid-mediated mobile colistin resistance (mcr) genes contributed to the global spread of colistin resistance.
Salloum, Tamara, Bitar, Ibrahim, Panossian, Balig, Araj, George F., Tokajian, Sima T., Hrabák, Jaroslav   +5 more
core   +1 more source

Combinations of colistin and bacteriocins prevent the selection of colistin resistance in Acinetobacter baumannii. [PDF]

Commun Biol
Acinetobacter baumannii is a multidrug-resistant nosocomial pathogen responsible for infections that are often difficult to treat. Here, we show that exposure of A. baumannii to the last-resort antibiotic colistin, which disrupts the outer membrane of Gram-negative bacteria, results in inner membrane permeabilization and depolarization, ultimately ...
Rubio T, Zur Nedden T, Zedek S, Raoux-Bardot D, Cottineau C, Belot L, Raynaud C, Oms T, Rodriguez-Vilallobos H, Jurenas D, Chenal A, Van Melderen L.   +11 more
europepmc   +3 more sources