Results 21 to 30 of about 57,221 (225)

Colistin-Resistant Acinetobacter baumannii: Beyond Carbapenem Resistance [PDF]

Clinical Infectious Diseases, 2015
With an increase in the use of colistin methansulfonate (CMS) to treat carbapenem-resistant Acinetobacter baumannii infections, colistin resistance is emerging.Patients with infection or colonization due to colistin-resistant A. baumannii were identified at a hospital system in Pennsylvania. Clinical data were collected from electronic medical records.
Zubair A, Qureshi, Lauren E, Hittle, Jessica A, O'Hara, Jesabel I, Rivera, Alveena, Syed, Ryan K, Shields, Anthony W, Pasculle, Robert K, Ernst, Yohei, Doi   +8 more
openaire   +2 more sources

Antibiotic residues and antibiotic-resistant bacteria in pig slurry used to fertilize agricultural fields [PDF]

, 2020
Pig manure may contain antibiotic residues, antibiotic-resistant bacteria or pathogens, which may reach the environment upon fertilization. During this study, 69 antibiotic residues belonging to 12 classes were quantified in 89 pig slurry samples.
Colson, Lander, Daeseleire, Els, De Carvalho Ferreira, Helena Cardoso, Decrop, Johan, Dewulf, Jeroen, Herman, Lieve, Heyndrickx, Marc, Meirlaen, Jurgen, Rasschaert, Geertrui, Van Elst, Daan   +9 more
core   +2 more sources

Circumventing colistin resistance by combining colistin and antimicrobial peptides to kill colistin-resistant and multidrug-resistant Gram-negative bacteria

Journal of Global Antimicrobial Resistance, 2020
Colistin is a 'last-line' antibiotic used to treat multidrug-resistant Gram-negative bacteria, but colistin resistance has emerged. Colistin normally binds to the lipid A moiety on the bacterial outer membrane, where it then destroys the bacterial membrane.
Kaitlin S. Witherell, Jason Price, Ashok D. Bandaranayake, James Olson, Douglas R. Call   +4 more
openaire   +3 more sources

Multi-drug resistant Gram-negative bacteria: antibiotic-resistance and new treatment strategies [PDF]

, 2017
In this editorial, we treat the multi-drug-resistance of microorganisms such as Klebsiella pneumonia (Kp) and Acinetobacter baumanii and the issues concerning the management of these infections.
Angelis, Massimiliano De, Mascellino, Maria Teresa, Oliva, Alessandra   +2 more
core   +1 more source

Synergistic Activity of Colistin-Containing Combinations against Colistin-Resistant Enterobacteriaceae [PDF]

Antimicrobial Agents and Chemotherapy, 2018
Resistance to colistin, a polypeptide drug used as an agent of last resort for the treatment of infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria, including carbapenem-resistant Enterobacteriaceae (CRE), severely limits treatment options and may even transform
Thea, Brennan-Krohn, Alejandro, Pironti, James E, Kirby   +2 more
openaire   +2 more sources

National survey of colistin resistance among carbapenemase-producing Enterobacteriaceae and outbreak caused by colistin-resistant OXA-48-producing Klebsiella pneumoniae, France, 2014 [PDF]

, 2016
From January 2014 to December 2014, 972 consecutive non-replicate carbapenemase-producing Enterobacteriaceae isolates from colonised or infected patients were collected at the Associated French National Reference Centre as part of the French national ...
Dortet, L, Jayol, A, Nordmann, P, Poirel, L   +3 more
core   +1 more source

Ursolic acid inhibits colistin efflux and curtails colistin resistant Enterobacteriaceae [PDF]

AMB Express, 2019
Colistin resistance in Enterobacteriaceae especially Klebsiella pneumoniae and Escherichia coli is driving the evolution of pan drug resistant strains. Screening a library of 13 plant nutraceuticals led to the identification of acetyl shikonin and ursolic acid, which exhibited synergy with colistin against extremely drug resistant (XDR) clinical ...
Niranjana Sri Sundaramoorthy, Harihar M. Mohan, Shankar Subramaniam, Thiagarajan Raman, Subramaniapillai Selva Ganesan, Aravind Sivasubamanian, Saisubramanian Nagarajan   +6 more
openaire   +4 more sources

Colistin Resistance among Enterobacterales Isolates: Underlying Mechanisms and Alternative Treatment Options

Journal of Pure and Applied Microbiology, 2023
Global dissemination of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria (GNB) such as carbapenemase-producing Enterobacterales has resulted in reviving colistin as a final therapeutic alternative. Colistin resistance
Amal F. Makled, Sahar A.M. Ali, Ahmed B. Mahmoud, Marwa E. Eltoukhy, Reem M. Elkholy, Athar F. Lasheen, Asmaa Mohammed Elbrolosy   +6 more
doaj   +1 more source

Evaluation of Plasmid Mediated Colistin Resistance in Colistin Resistant Gram-negative Bacilli

Journal of Kermanshah University of Medical Sciences, 2023
Background: Infections caused by carbapenem-resistant gram-negative bacteria are treated with colonistin as a last resort. However, the increased resistance in recent years is significant for treating multiple drug-resistant infections. Objectives: This study aimed to determine the resistance genes mobile colistin resistance (mcr)-1 and mcr-2 in the ...
Yeliz Tanriverdi Cayci, Kubra Hacieminoglu Ulker, Demet Gur Vural, Kemal Bilgin, Asuman Birinci   +4 more
openaire   +1 more source

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis [PDF]

, 2018
Background: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging.
Abu Sin, Muna, Andrasevic, Arjana Tambic, Aracil, Belen, Asensio, Angel, Billstrom, Hanna, Borg, Michael A., Budimir, Ana, Burns, Karen, Canica, Manuela, Cassini, Alessandro, Catry, Boudewijn, Cecchini, Michele, Coignard, Bruno, Colomb-Cotinat, Melanie, Daikos, George L., de Greeff, Sabine C., Deptula, Aleksander, Devleesschauwer, Brecht, Dobreva, Elina Georgieva, Dsstat, Patrizio Pezzotti, Dumpis, Uga, Eckmanns, Tim, Elstrom, Petter, Fernandes, Paulo Andre, Gagliotti, Carlo, Gikas, Achilleas, Guolaugsson, Olafur, Hajdu, Agnes, Haller, Sebastian, Hogberg, Liselotte Diaz, Hopkins, Susan, Hoxha, Ana, Hryniewicz, Waleria, Ivanov, Ivan Nikolaev, Ivanova, Marina, Jalava, Jari, Johnson, Alan, Klavs, Irena, Koek, Mayke B. G., Kolman, Jana, Kontopidou, Flora, Korosec, Ales, Kretzschmar, Mirjam E., Kristinsson, Karl G., Larsson, Sofie, Latour, Katrien, Litvova, Slavka, Liuimiene, Agne, Lyytikainen, Outi, Manageiro, Vera, Martin, Pille, Mertens, Karl, Monen, Jos C. M., Monnet, Dominique L., Murchan, Stephen, Nogueira, Paulo Jorge, Oliveira, Tiago Cravo, Olsen, Stefan Schytte, Ouakrim, Driss Ait, Paphitou, Niki, Perez-Vazquez, Maria, Perrin, Monique, Plachouras, Diamantis, Popescu, Gabriel Adrian, Quattrocchi, Annalisa, Reilly, Jacqui S., Schreterova, Eva, Serban, Roxana Ioana, Simonsen, Gunnar Skov, Sonksen, Ute Wolff, Soprek, Silvija, Stefkovicova, Maria, Strauss, Reinhild, Struelens, Marc J., Struyf, Thomas, Suetens, Carl, Toth, Akos, Tsiodras, Sotirios, Zabicka, Dorota, Zemlickova, Helena   +79 more
core   +6 more sources