Results 21 to 30 of about 2,359,106 (231)
A Clinico-Microbiological Study of Blood Stream Infections in a Tertiary Referral Hospital: Colistin Resistance & Challenges [PDF]
, 2023 Carbapenems, frequently used for the treatment of infections caused by Multidrug-resistant (MDR) Gram-negative bacteria (GNB) are being reported with increased resistance rate.
Jyoti Chaudhary +2 more
core +1 more source
Emerging Microbes and Infections, 2021 Infections caused by extensively drug-resistant (XDR) Acinetobacter nosocomialis have become a challenging problem. The frequent use of colistin as the last resort drug for XDR bacteria has led to the emergence of colistin-resistant A.
Ya-Sung Yang +10 more
doaj +1 more source
Asian Pacific Journal of Tropical Medicine, 2022 Objective: To find a proper method to assess colistin resistance in multidrug resistant Gram negative bacteria (MDR-GNB) on a routine basis in resource limited settings. Methods: Clinical samples were processed.
Shubham Chauhan +4 more
doaj +1 more source
Transition of colistin dependence into colistin resistance in Acinetobacter baumannii [PDF]
Scientific Reports, 2017 AbstractWe recently demonstrated a high rate of colistin dependence in Acinetobacter baumannii isolates exposed to colistin in vitro. In the present study, we obtained a colistin-resistant (H08-391R) and colistin-dependent mutant (H08-391D) from a colistin-susceptible parental strain (H08-391). We found that the colistin-dependent mutant converted into
Lee, Ji-Young +2 more
openaire +3 more sources
Presence of Colistin- and Tigecycline-Resistant Klebsiella pneumoniae ST29 in Municipal Wastewater Influents in Japan [PDF]
, 2021 The aim of this study was to investigate the presence of colistin- and/or tigecycline-resistant Klebsiella spp. in influents from four wastewater treatment plants (WWTPs), which partly reflect the gut microbiome of human populations.
Nagano, Yukiko +8 more
core +1 more source
International Journal of Antimicrobial Agents, 2022 The plasmid-mediated bacterial colistin-resistant gene, mcr, is of global concern in clinical healthcare. However, there are few reports of surveillance for mcr in Japan. The aim of this study was to assess the prevalence of colistin resistance by identifying nine mcr genes in extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae and ...
Yasuhide Kawamoto +12 more
openaire +2 more sources
mSphere, 2020 Infections by multidrug-resistant Gram-negative bacteria are increasingly common, prompting the renewed interest in the use of colistin. Colistin specifically targets Gram-negative bacteria by interacting with the anionic lipid A moieties of ...
Axel B. Janssen +6 more
doaj +1 more source
A link between pH homeostasis and colistin resistance in bacteria
Scientific Reports, 2021 Colistin resistance is complex and multifactorial. DbcA is an inner membrane protein belonging to the DedA superfamily required for maintaining extreme colistin resistance of Burkholderia thailandensis. The molecular mechanisms behind this remain unclear.
Pradip R. Panta, William T. Doerrler
doaj +1 more source
, 2022 Background: A collection of human-epidemiologically unrelated S. enterica strains collected over a 3-year period (2016 to 2018) in Italy by the national surveillance Enter-Net Italia was analysed.
Claudia Lucarelli +18 more
core +1 more source
Journal of Global Antimicrobial Resistance, 2020 Colistin is a 'last-line' antibiotic used to treat multidrug-resistant Gram-negative bacteria, but colistin resistance has emerged. Colistin normally binds to the lipid A moiety on the bacterial outer membrane, where it then destroys the bacterial membrane.
Kaitlin S. Witherell +4 more
openaire +3 more sources