Results 21 to 30 of about 2,002 (155)

Characterization of the Complete Nucleotide Sequences of mcr-1-Encoding Plasmids From Enterobacterales Isolates in Retailed Raw Meat Products From the Czech Republic

Frontiers in Microbiology, 2021
The aim of our study was to determine complete nucleotide sequence of mcr-1-carrying plasmids from Enterobacterales isolates recovered from domestic and imported raw retailed meat and compare them with plasmids available at the GenBank sequence database.
Marketa Zelendova, Marketa Zelendova, Costas C. Papagiannitsis, Costas C. Papagiannitsis, Costas C. Papagiannitsis, Costas C. Papagiannitsis, Adam Valcek, Adam Valcek, Adam Valcek, Matej Medvecky, Matej Medvecky, Ibrahim Bitar, Ibrahim Bitar, Jaroslav Hrabak, Jaroslav Hrabak, Tereza Gelbicova, Alzbeta Barakova, Alzbeta Barakova, Iva Kutilova, Iva Kutilova, Renata Karpiskova, Monika Dolejska, Monika Dolejska, Monika Dolejska   +23 more
doaj   +1 more source

Emergence of a blaNDM-5 Carrying IncHI2/IncHI2A Plasmid in a Multidrug Resistant Clinical ST1431 Escherichia coli Strain

Infection and Drug Resistance
Xu Lin,* Zhiwen Lin,* Da Chen, Renhuai Huang, Hui Liang First Department of General Surgery, Zhuhai People’s Hospital (Zhuhai Hospital Affiliated to Jinan University), Zhuhai City, Guangdong Province, People’s Republic of China*These authors ...
Lin X, Lin Z, Chen D, Huang R, Liang H
doaj   +3 more sources

Emergence of a novel hybrid mcr-1-bearing plasmid in an NDM-7-producing ST167 Escherichia coli strain of clinical origin

Frontiers in Microbiology, 2022
Colistin is considered as an antibiotic of ‘last resort’ for the treatment of lethal infections caused by carbapenem-resistant Enterobacterales (CRE), dissemination of plasmid-borne colistin resistance gene mcr-1, particularly into CRE, resulting in the ...
Shuang Xia, Wei Wang, Jing Cheng, Jing Cheng, Tingting Zhang, Tingting Zhang, Ziwei Xia, Ziwei Xia, Xiaoyu Zhao, Xiaoyu Zhao, Yungang Han, Yonghong Li, Yonghong Li, Xiufang Shi, Xiufang Shi, Shangshang Qin, Shangshang Qin   +16 more
doaj   +1 more source

First IncHI2 Plasmid Carrying mcr-9.1 , bla _VIM-1 , and Double Copies of bla _KPC-3 in a Multidrug-Resistant Escherichia coli Human Isolate

mSphere, 2021
We report a novel IncHI2 plasmid coharboring blaVIM-1blaKPC-3mcr-9.1Escherichia coliblaVIM-1mcr-9.1903blaKPC ...
Serena Simoni, Marina Mingoia, Andrea Brenciani, Maria Carelli, Maria M. Lleò, Giovanni Malerba, Carla Vignaroli   +6 more
doaj   +1 more source

Plasmid double locus sequence typing for IncHI2 plasmids, a subtyping scheme for the characterization of IncHI2 plasmids carrying extended-spectrum β-lactamase and quinolone resistance genes [PDF]

Journal of Antimicrobial Chemotherapy, 2010
IncHI2 plasmids are frequently encountered in clinical enterobacterial strains associated with the dissemination of relevant antimicrobial resistance genes. These plasmids are usually >250 kb, and technical difficulties can impair plasmid DNA purification and comparison by restriction fragment length polymorphism. We analysed the available IncHI2 whole
Garcia-Fernández A., Carattoli A.
openaire   +3 more sources

Spread of oqxAB in Salmonella enterica serotype Typhimurium predominantly by IncHI2 plasmids [PDF]

Journal of Antimicrobial Chemotherapy, 2013
To investigate the prevalence and genetic environment of the multiresistance gene oqxAB in Salmonella enterica serotype Typhimurium isolated from food-producing animals.In this study, 63 Salmonella enterica serotype Typhimurium isolates were analysed for the presence of plasmid-mediated quinolone resistance determinants and mutations in the quinolone ...
Liang, Li, Xiaoping, Liao, Yurong, Yang, Jian, Sun, Lulu, Li, Baotao, Liu, Shoushen, Yang, Jun, Ma, Xue, Li, Qijing, Zhang, Yahong, Liu   +10 more
openaire   +2 more sources

Mapping studies and genetic analysis of transfer genes of the multi-resistant IncHI2 plasmid, R478 [PDF]

FEMS Microbiology Letters, 1999
A bank of transfer-defective Tn7 insertion mutants of the multi-resistant IncHI2 megaplasmid, R478, was generated. Complementation analysis of these mutations identified a large 144-kb transfer-associated region of R478. A 6.8-kb segment from the transfer region was sequenced.
D T, Page, K F, Whelan, E, Colleran
openaire   +3 more sources

Emergence of IncHI2 Plasmids With Mobilized Colistin Resistance (mcr)-9 Gene in ESBL-Producing, Multidrug-Resistant Salmonella Typhimurium and Its Monophasic Variant ST34 From Food-Producing Animals in Italy

Frontiers in Microbiology, 2021
A collection of 177 genomes of Salmonella Typhimurium and its monophasic variant isolated in 2014–2019 from Italian poultry/livestock (n = 165) and foodstuff (n = 12), previously screened for antimicrobial susceptibility and assigned to ST34 and single ...
Elena Lavinia Diaconu, Patricia Alba, Fabiola Feltrin, Paola Di Matteo, Manuela Iurescia, Eleonora Chelli, Valentina Donati, Ilaria Marani, Angelo Giacomi, Alessia Franco, Virginia Carfora   +10 more
doaj   +1 more source

Silent spread of mobile colistin resistance gene mcr-9.1 on IncHI2 ‘superplasmids’ in clinical carbapenem-resistant Enterobacterales [PDF]

Clinical Microbiology and Infection, 2021
mcr-9.1 is a newly described mobile colistin resistance gene. We have noted its presence in multiple species of carbapenem-resistant Enterobacterales (CRE) from our institution. We aimed to determine the clinical features, genomic context and phenotypic impact of mcr-9.1 carriage in a series of patients between 2010 and 2019.We identified 32 patients ...
Nenad, Macesic, Luke V, Blakeway, James D, Stewart, Jane, Hawkey, Kelly L, Wyres, Louise M, Judd, Ryan R, Wick, Adam W, Jenney, Kathryn E, Holt, Anton Y, Peleg   +9 more
openaire   +2 more sources

Acquisition and diffusion of bla CTX-M-9 gene by R478-IncHI2 derivative plasmids. [PDF]

FEMS microbiology letters, 2007
Escherichia coli and Salmonella enterica isolates carrying the bla(CTX-M-9) gene located on plasmids prevailed at the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain in the 1996-1999 period. The bla(CTX-M-9)-carrying plasmids showed a great variability in size, suggesting the mobilization of the gene among different plasmid scaffolds. The aim of
García A, Navarro F, Miró E, Villa L, Mirelis B, Coll P, Carattoli A.   +6 more
openaire   +4 more sources