Results 21 to 30 of about 1,946 (157)

Silent spread of mobile colistin resistance gene mcr-9.1 on IncHI2 ‘superplasmids’ in clinical carbapenem-resistant Enterobacterales [PDF]

Clinical Microbiology and Infection, 2021
mcr-9.1 is a newly described mobile colistin resistance gene. We have noted its presence in multiple species of carbapenem-resistant Enterobacterales (CRE) from our institution. We aimed to determine the clinical features, genomic context and phenotypic impact of mcr-9.1 carriage in a series of patients between 2010 and 2019.We identified 32 patients ...
Nenad, Macesic, Luke V, Blakeway, James D, Stewart, Jane, Hawkey, Kelly L, Wyres, Louise M, Judd, Ryan R, Wick, Adam W, Jenney, Kathryn E, Holt, Anton Y, Peleg   +9 more
openaire   +2 more sources

First IncHI2 Plasmid Carrying mcr-9.1 , bla _VIM-1 , and Double Copies of bla _KPC-3 in a Multidrug-Resistant Escherichia coli Human Isolate

mSphere, 2021
We report a novel IncHI2 plasmid coharboring blaVIM-1blaKPC-3mcr-9.1Escherichia coliblaVIM-1mcr-9.1903blaKPC ...
Serena Simoni, Marina Mingoia, Andrea Brenciani, Maria Carelli, Maria M. Lleò, Giovanni Malerba, Carla Vignaroli   +6 more
doaj   +1 more source

Emergence of IncHI2 Plasmids With Mobilized Colistin Resistance (mcr)-9 Gene in ESBL-Producing, Multidrug-Resistant Salmonella Typhimurium and Its Monophasic Variant ST34 From Food-Producing Animals in Italy

Frontiers in Microbiology, 2021
A collection of 177 genomes of Salmonella Typhimurium and its monophasic variant isolated in 2014–2019 from Italian poultry/livestock (n = 165) and foodstuff (n = 12), previously screened for antimicrobial susceptibility and assigned to ST34 and single ...
Elena Lavinia Diaconu, Patricia Alba, Fabiola Feltrin, Paola Di Matteo, Manuela Iurescia, Eleonora Chelli, Valentina Donati, Ilaria Marani, Angelo Giacomi, Alessia Franco, Virginia Carfora   +10 more
doaj   +1 more source

Spread of oqxAB in Salmonella enterica serotype Typhimurium predominantly by IncHI2 plasmids [PDF]

Journal of Antimicrobial Chemotherapy, 2013
To investigate the prevalence and genetic environment of the multiresistance gene oqxAB in Salmonella enterica serotype Typhimurium isolated from food-producing animals.In this study, 63 Salmonella enterica serotype Typhimurium isolates were analysed for the presence of plasmid-mediated quinolone resistance determinants and mutations in the quinolone ...
Liang, Li, Xiaoping, Liao, Yurong, Yang, Jian, Sun, Lulu, Li, Baotao, Liu, Shoushen, Yang, Jun, Ma, Xue, Li, Qijing, Zhang, Yahong, Liu   +10 more
openaire   +2 more sources

Genomic Analysis of a Mcr-9.1-Harbouring IncHI2-ST1 Plasmid from Enterobacter

Antibiotics, 2022
This study analyzed the resistome, virulome and mobilome of an MCR-9-producing Enterobacter sp. identified in a muscle sample of seabream (Sparus aurata), collected in a land tank from multitrophic fish farming production. Average Nucleotide Identity analysis identified INSAq77 at the species level as an Enterobacter ludwigii INSAq77 strain that was ...
Vera Manageiro, Vanessa Salgueiro, Tânia Rosado, Narcisa M. Bandarra, Eugénia Ferreira, Terry Smith, Elsa Dias, Manuela Caniça   +7 more
openaire   +4 more sources

Mapping studies and genetic analysis of transfer genes of the multi-resistant IncHI2 plasmid, R478 [PDF]

FEMS Microbiology Letters, 1999
A bank of transfer-defective Tn7 insertion mutants of the multi-resistant IncHI2 megaplasmid, R478, was generated. Complementation analysis of these mutations identified a large 144-kb transfer-associated region of R478. A 6.8-kb segment from the transfer region was sequenced.
D T, Page, K F, Whelan, E, Colleran
openaire   +3 more sources

Acquisition and diffusion of bla CTX-M-9 gene by R478-IncHI2 derivative plasmids. [PDF]

FEMS microbiology letters, 2007
Escherichia coli and Salmonella enterica isolates carrying the bla(CTX-M-9) gene located on plasmids prevailed at the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain in the 1996-1999 period. The bla(CTX-M-9)-carrying plasmids showed a great variability in size, suggesting the mobilization of the gene among different plasmid scaffolds. The aim of
García A, Navarro F, Miró E, Villa L, Mirelis B, Coll P, Carattoli A.   +6 more
openaire   +4 more sources

Healthcare-associated infections caused by chlorhexidine-tolerant Serratia marcescens carrying a promiscuous IncHI2 multi-drug resistance plasmid in a veterinary hospital

PLoS ONE, 2022
The bacterium Serratia marcescens can cause opportunistic infections in humans and in animals. In veterinary settings, the diversity, reservoirs and modes of transmission of this pathogen are poorly understood.
Joanne L. Allen, Nicholas P. Doidge, Rhys N. Bushell, Glenn F. Browning, Marc S. Marenda   +4 more
doaj   +2 more sources

IncHI2 Plasmids Are the Key Vectors Responsible for oqxAB Transmission among Salmonella Species [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACT This study reported and analyzed the complete sequences of two oqxAB -bearing IncHI2 plasmids harbored by a clinical Salmonella enterica serovar Typhimurium strain and an S . Indiana strain of animal origin, respectively.
Marcus Ho-yin Wong, Edward Wai-chi Chan, Liqi Xie, Ruichao Li, Sheng Chen   +4 more
openaire   +2 more sources

Emergence of blaNDM-9-bearing tigecycline-resistant Klebsiella aerogenes of chicken origin

Journal of Global Antimicrobial Resistance, 2021
: Objectives: The aim of this study was to characterise a tigecycline-resistant blaNDM-9-bearing Klebsiella aerogenes strain (HNHF1) of chicken origin.
Yan Li, Qian Wang, Xia Xiao, Ruichao Li, Zhiqiang Wang   +4 more
doaj   +1 more source