Emergence of IncHI2 Plasmid-Harboring blaNDM-5 from Porcine Escherichia coli Isolates in Guangdong, China [PDF]
Carbapenem resistance has posed potential harmful risks to human and animals. The objectives of this study were to understand the prevalence of blaNDM-5 in pigs and investigate the molecular characteristics of NDM-5-producing Escherichia coli isolates in
Zhenbao Ma +6 more
doaj +2 more sources
First IncHI2 Plasmid Carrying mcr-9.1 , bla VIM-1 , and Double Copies of bla KPC-3 in a Multidrug-Resistant Escherichia coli Human Isolate [PDF]
We report a novel IncHI2 plasmid coharboring blaVIM-1blaKPC-3mcr-9.1Escherichia coliblaVIM-1mcr-9.1903blaKPC ...
Serena Simoni +6 more
doaj +2 more sources
Fitness cost of a mcr-1-carrying IncHI2 plasmid. [PDF]
IncHI2 is a common type of large mcr-1-carrying plasmids that have been found worldwide. Large plasmids could impose metabolic burden for host bacterial strains, we therefore examine the stability and fitness cost of a mcr-1-carrying 265.5-kb IncHI2 ...
Ke Ma, Yu Feng, Zhiyong Zong
doaj +2 more sources
Genomic Analysis of an IMP-1-Producing Atlantibacter hermannii Bloodstream Isolate Carrying a Transferable blaIMP-1-Harbouring IncHI2/pST1 Plasmid Related to Historical Enterobacterales Plasmids in Japan [PDF]
Atlantibacter hermannii is an uncommon member of the Enterobacterales rarely associated with human infection, and genomic data on antimicrobial resistance in this species remain limited. Carbapenemase-producing A.
Takashi Okanda +13 more
doaj +2 more sources
Transferable IncHI2-Associated blaLAP-2 and blaCTX-M-55 Resistance Platforms in Foodborne Salmonella [PDF]
Extended-spectrum β-lactamase genes in foodborne Salmonella enterica can disseminate through mobile multidrug-resistance platforms. IncHI2 plasmids are important resistance vehicles capable of carrying complex resistance regions and facilitating their ...
Zeqiang Zhan +8 more
doaj +2 more sources
Genomic Insights into a Colistin-Resistant Uropathogenic Escherichia coli Strain of O23:H4-ST641 Lineage Harboring mcr-1.1 on a Conjugative IncHI2 Plasmid from Egypt [PDF]
The reintroduction of colistin, a last-resort antibiotic for multidrug-resistant pathogens, resulted in the global spread of plasmid-mediated mobile colistin resistance (mcr) genes.
Azza S. Zakaria +2 more
doaj +2 more sources
During a regular monitoring of antimicrobial resistance in a farrowing farm in Southern China, 117 Escherichia coli isolates were obtained from sows and piglets.
Jian Sun +2 more
exaly +3 more sources
IncHI2 Plasmids Are Predominant in Antibiotic-Resistant Salmonella Isolates
The wide usage of antibiotics contributes to the increase in the prevalence of antibiotic-resistant Salmonella. Plasmids play a critical role in horizontal transfer of antibiotic resistance markers in Salmonella.
Xianming Shi, Xiujuan Zhou, Chunlei Shi
exaly +3 more sources
Potential dissemination of IncHI2/IncHI2A plasmids carrying mcr-9.4 complex transposon in chicken-derived Enterobacter hormaechei [PDF]
The escalating global prevalence of antimicrobial resistance(AMR) represents a critical public health challenge, particularly concerning the compromised efficacy of polymyxins—essential therapeutic agents against carbapenem-resistant Gram-negative ...
Panpan Liu +6 more
doaj +2 more sources
Background: Co-harbouring of carbapenem and colistin resistance genes in multidrug-resistant Enterobacterales strains poses a serious public health problem. In this study, an MCR-1.1 and NDM-5 coproducing Escherichia coli strain named EC6563 was isolated
Jintao He, Jingjing Quan, Xiaofan Zhang
exaly +3 more sources

