Emergence of IncHI2 Plasmid-Harboring blaNDM-5 from Porcine Escherichia coli Isolates in Guangdong, China [PDF]
Pathogens, 2021 Carbapenem resistance has posed potential harmful risks to human and animals. The objectives of this study were to understand the prevalence of blaNDM-5 in pigs and investigate the molecular characteristics of NDM-5-producing Escherichia coli isolates in
Zhenbao Ma +6 more
doaj +3 more sources
Genomic Characterisation of a Multiple Drug Resistant IncHI2 ST4 Plasmid in Escherichia coli ST744 in Australia [PDF]
Microorganisms, 2020 Antibiotic resistance genes (ARGs) including those from the blaCTX-M family and mcr-1 that encode resistance to extended spectrum β–lactams and colistin, respectively, have been linked with IncHI2 plasmids isolated from swine production facilities ...
Tiziana Zingali +4 more
doaj +3 more sources
Potential spread of mcr-9-carrying IncHI2 plasmids in Enterobacter hormaechei in Vietnam
Journal of Global Antimicrobial Resistance, 2021 : Objectives: Mobile colistin resistance (mcr) genes are widely distributed around the world. To date, ten major variants of mcr genes are known (mcr-1 to mcr-10).
Van Thi Thu Ha +7 more
doaj +3 more sources
IncHI2 Plasmids Are Predominant in Antibiotic-Resistant Salmonella Isolates [PDF]
Frontiers in Microbiology, 2016 The wide usage of antibiotics contributes to the increase in the prevalence of antibiotic-resistant Salmonella. Plasmids play a critical role in horizontal transfer of antibiotic resistance markers in Salmonella.
Wenyao Chen +5 more
doaj +3 more sources
Fitness cost of a mcr-1-carrying IncHI2 plasmid.
PLoS ONE, 2018 IncHI2 is a common type of large mcr-1-carrying plasmids that have been found worldwide. Large plasmids could impose metabolic burden for host bacterial strains, we therefore examine the stability and fitness cost of a mcr-1-carrying 265.5-kb IncHI2 ...
Ke Ma, Yu Feng, Zhiyong Zong
doaj +4 more sources
Characterisation of blaNDM-5-bearing IncHI2 plasmid from Escherichia fergusonii in China
Journal of Global Antimicrobial ResistanceObjective: Carbapenems are considered to be the last resort for serious infections caused by multidrug-resistant Gram-negative bacteria, and the emergence of carbapenem-resistant Enterobacteriaceae has posed a serious threat to human health.
Yan Shi +5 more
doaj +3 more sources
Complete Sequences of Multiple-Drug Resistant IncHI2 ST3 Plasmids in Escherichia coli of Porcine Origin in Australia [PDF]
Frontiers in Sustainable Food Systems, 2019 IncHI2 ST3 plasmids are known carriers of multiple antimicrobial resistance genes. Complete plasmid sequences from multiple drug resistant Escherichia coli circulating in Australian swine is however limited.
Ethan R. Wyrsch +7 more
doaj +2 more sources
oqxAB-Positive IncHI2 Plasmid pHXY0908 Increase Salmonella enterica Serotype Typhimurium Strains Tolerance to Ciprofloxacin [PDF]
Frontiers in Cellular and Infection Microbiology, 2019 Salmonella enterica serotype Typhimurium is a major global food-borne pathogen and causes life-threatening infections. Although the resistance mechanisms to fluoroquinolones in S.
Xinlei Lian +23 more
doaj +3 more sources
Transmissible ST3-IncHI2 Plasmids Are Predominant Carriers of Diverse Complex IS26-Class 1 Integron Arrangements in Multidrug-Resistant Salmonella [PDF]
Frontiers in Microbiology, 2018 Diverse mobile genetic elements (MGEs) including plasmids, insertion sequences, and integrons play an important role in the occurrence and spread of multidrug resistance (MDR) in bacteria.
Hang Zhao +4 more
doaj +3 more sources
One Health at Risk: Plasmid-Mediated Spread of mcr-1 Across Clinical, Agricultural, and Environmental Ecosystems [PDF]
AntibioticsThe global dissemination of plasmid-mediated mcr genes, which confer resistance to the last-resort antibiotic colistin, represents a critical public health challenge driven by the interplay of clinical, agricultural, and environmental factors.
Abdelaziz Touati +5 more
doaj +2 more sources