Results 221 to 230 of about 299,331 (269)

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Complete genome sequence of <i>Sphingobium yanoikuyae</i> strain K1B isolated from the pea rhizosphere. [PDF]

Microbiol Resour Announc
Guro PV, Sekste EA, Azarova TS, Shaposhnikov AI, Yuzikhin OS, Shahnazarova VY, Vishnevskaya NA, Lebedinskii MI, Safronova VI, Belimov AA, Sazanova AL.   +10 more
europepmc   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

Smart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang, Huan Tang, Yue Pan, Mingle Li, Weijie Zhao, Kai Liu   +5 more
wiley   +1 more source

Polyclonal emergence of virulent, multidrug-resistant <i>Edwardsiella tarda</i> lineages associated with bacillary necrosis of <i>Pangasius</i> in striped catfish farms. [PDF]

Appl Environ Microbiol
Ho T-T, Diep P-H, Tu VQ, Ly KDN, Le NP, Dang OTH, Millard AD, Nguyen T-T, Nguyen CD, Diep BA, Ngo TPH, Pham CT, Nguyen QB, Hoang HA.   +13 more
europepmc   +1 more source

Periplasmic SacB as a robust counter-selection tool for genome engineering in the polyploid bacterium <i>Zymomonas mobilis</i>. [PDF]

Microbiol Spectr
Fuchino K, Astraios C, Daniel R, Grimshaw J, Banzhaf M, Vollmer W.   +5 more
europepmc   +1 more source

Intrinsically disordered protein droplet-enhanced oligonucleotide assembly enables rapid oligonucleotide-to-protein expression. [PDF]

Nucleic Acids Res
Ueno T, Minagawa Y, Okada Y, Noji H.
europepmc   +1 more source

Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation. [PDF]

Nat Commun
Schnabel L, Osorio-Valeriano M, Perez-Borrajero C, Steinchen W, Mais CN, Simon B, Hanßmann J, Thamm M, Hennig J, Bange G, Thanbichler M.   +10 more
europepmc   +1 more source

Integrative analysis of fitness and metabolic effects of a large multidrug-resistant plasmid in <i>Salmonella</i> across diverse serovars. [PDF]

Microb Genom
Su YT, Li ZX, Li PW, Yang MT, Sun RY, Xu Y, Wang D, Sun J, Liao XP, Fang LX.   +9 more
europepmc   +1 more source

Intracellular competitions reveal the combination of active partitioning and addiction mechanisms as most advantageous for low-copy plasmid fitness

Effe J, Santer M, Wang Y, Feenstra TE, Hülter NF, Dagan T.   +5 more
europepmc   +1 more source