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Plasmid partitioning systems of conjugative plasmids from Clostridium perfringens
Plasmid, 2015Many pathogenic strains of Clostridium perfringens carry several highly similar toxin or antibiotic resistance plasmids that have 35 to 40 kb of very closely related syntenous sequences, including regions that carry the genes encoding conjugative transfer, plasmid replication and plasmid maintenance functions.
Vicki Adams +4 more
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Segregation of the yeast plasmid: similarities and contrasts with bacterial plasmid partitioning
Plasmid, 2004The high copy yeast plasmid 2 microm circle, like the well-studied low copy bacterial plasmids, utilizes two partitioning proteins and a cis-acting 'centromere'-like sequence for its stable propagation. Functionally, though, the protein and DNA constituents of the two partitioning systems are quite distinct.
Makkuni, Jayaram +3 more
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1989
Plasmids are autonomously replicating elements that are dispensable for cell viability and are therefore vulnerable to loss from the growing cells. However, naturally occurring plasmids are very stably maintained in populations of the host bacteria. Thus, the individual copies must be distributed within the dividing cell in such a way as to ensure that
Ann L. Abeles, Stuart J. Austin
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Plasmids are autonomously replicating elements that are dispensable for cell viability and are therefore vulnerable to loss from the growing cells. However, naturally occurring plasmids are very stably maintained in populations of the host bacteria. Thus, the individual copies must be distributed within the dividing cell in such a way as to ensure that
Ann L. Abeles, Stuart J. Austin
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P1 Plasmid Partition: A Mutational Analysis of ParB
Journal of Molecular Biology, 1996P1 plasmid partition to daughter cells requires plasmid proteins, ParA and ParB, and a centromere analog, parS, to which ParB binds. ParA and ParB decrease the loss frequencies of some low copy number plasmid vectors with parS inserts, as well as that of P1 itself, more than 100-fold.
Malgorzata Lobocka
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Molecular Microbiology, 1997
The partition system of the P1 plasmid, P1parconsists of the ParA and ParB proteins and a cis‐acting site, parS. It is responsible for the orderly segregation of plasmid copies to daughter cells. Plasmids with null mutations in parA or parB replicate normally, but missegregate.
B, Youngren, S, Austin
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The partition system of the P1 plasmid, P1parconsists of the ParA and ParB proteins and a cis‐acting site, parS. It is responsible for the orderly segregation of plasmid copies to daughter cells. Plasmids with null mutations in parA or parB replicate normally, but missegregate.
B, Youngren, S, Austin
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Cell, 1983
Plasmids that replicate using the replication origin (oriC) of the E. coli chromosome are not stably inherited through cell division, but can be stabilized by joining with a particular segment of F plasmid that presumably provides the partition function.
Teru Ogura, S Hiraga, Sota Hiraga
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Plasmids that replicate using the replication origin (oriC) of the E. coli chromosome are not stably inherited through cell division, but can be stabilized by joining with a particular segment of F plasmid that presumably provides the partition function.
Teru Ogura, S Hiraga, Sota Hiraga
exaly +3 more sources
Partition Systems of Bacterial Plasmids
2014Plasmids, as extrachromosomal elements, bear the burden of ensuring their own faithful segregation at cell division. This chapter reviews partition systems, which are, in general, systems that actively dictate the specific localization of plasmids inside the bacterial cell and coordinate this localization with the bacterial cell cycle.
Barbara E. Funnell, Roderick A. Slavcev
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Plasmid partitioning superstructure system
Science, 2015DNA Segregation Partitioning and sharing DNA between dividing cells is critical for all domains of life. Prokaryotes must share certain plasmids as well as their genomic DNA to survive. Schumacher et al. studied the partition system that segregates a conjugative plasmid in the prokaryote Sulfolobus. The system consists of three proteins.
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Partitioning of the pSC101 Plasmid during Cell Division
1985It is generally accepted that a mechanism must exist for ensuring that each of the products of a bacterial cell division receives a copy of the chromosome. However, until recently, the existence of a specific mechanism for actively distributing extrachromosomal elements such as plasmids to daughter cells was less clear.
S N, Cohen +4 more
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Clustering versus random segregation of plasmids lacking a partitioning function: a plasmid paradox?
Plasmid, 2003Plasmids lacking a functional partition system are randomly distributed to the daughter cells; plasmid-free daughter cells are formed with a frequency of (1/2)2n per cell and cell generation where 2n is the (average) copy number at cell division. Hence, the unit of segregation is one plasmid copy. However, plasmids form clusters in the cells.
Nordström, K., Gerdes, K.
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