Results 171 to 180 of about 18,160 (210)

Limits of rapid diagnostics: genomic and structural insights into OXA-48-like mediated carbapenem resistance in <i>Escherichia coli</i>. [PDF]

Front Microbiol
Diab AA, Jalal D, Fadel YM, Samir O, Shalaby L, Elanany M, Abo-Elmaaty SA, Aziz RK, Sayed AA, Hassan MG.   +9 more
europepmc   +1 more source

Genomic characterization of the multidrug-resistant IncP-2 plasmid pPAMS in a clinical isolate Pseudomonas aeruginosa. [PDF]

BMC Microbiol
Dong L, Yuan X, Li S, Hou Z, Wang Y, Li M, Ji B.   +6 more
europepmc   +1 more source

Co-occurrence of plasmid-mediated colistin resistance gene, mcr-1 and bla_CTX-M in multidrug-resistant Escherichia coli isolates from calves in Iran. [PDF]

Sci Rep
Haeili M, Naghibi Biji SMR, Alsahlani F, Moghaddasi K, Omrani M, Ghodousi A, Cirillo DM.   +6 more
europepmc   +1 more source

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Plasmid-mediated quinolone resistance

Expert Review of Anti-Infective Therapy, 2008
The first plasmid-mediated gene involved in quinolone resistance (qnrA1) was reported in 1998. It codes for a pentapeptide-repeat protein that protects type II topoisomerases from quinolones. Additional related plasmid-mediated genes (qnrB, qnrS and qnrC) and chromosomal homologs of them have also been discovered.
Luis Martínez-Martínez, J M Rodríguez-Martínez, Jorge Calvo   +2 more
exaly   +3 more sources

Quinolone resistance from a transferable plasmid

Lancet, The, 1998
Bacteria can mutate to acquire quinolone resistance by target alterations or diminished drug accumulation. Plasmid-mediated resistance to quinolones in clinical isolates has been claimed but not confirmed. We investigated whether a multiresistance plasmid could transfer resistance to quinolones between bacteria.We transferred resistance between strains
Luis Martínez-Martínez, Alvaro Pascual, G A Jacoby   +2 more
exaly   +3 more sources

Plasmid-mediated quinolone resistance: an update

Journal of Infection and Chemotherapy, 2011
In 1998, the first plasmid-mediated gene involved in quinolone resistance (currently named qnrA1) was reported. Extra qnr-like plasmid-mediated genes (qnrB, qnrS, qnrC, qnrD) and their chromosomal homologues have also been characterized. These genes code for a pentapeptide repeat protein that protects type II topoisomerases from quinolones. Since then,
J M Rodríguez-Martínez, Alvaro Pascual, Luis Martínez-Martínez   +2 more
exaly   +3 more sources

Plasmid-mediated quinolone resistance: Two decades on

Drug Resistance Updates, 2016
After two decades of the discovery of plasmid-mediated quinolone resistance (PMQR), three different mechanisms have been associated to this phenomenon: target protection (Qnr proteins, including several families with multiple alleles), active efflux pumps (mainly QepA and OqxAB pumps) and drug modification [AAC(6')-Ib-cr acetyltransferase].
J M Rodríguez-Martínez, Jesus Machuca, Jorge Calvo   +2 more
exaly   +3 more sources

The worldwide emergence of plasmid-mediated quinolone resistance

The Lancet Infectious Diseases, 2006
Fluoroquinolone resistance is emerging in gram-negative pathogens worldwide. The traditional understanding that quinolone resistance is acquired only through mutation and transmitted only vertically does not entirely account for the relative ease with which resistance develops in exquisitely susceptible organisms, or for the very strong association ...
Ari, Robicsek, George A, Jacoby, David C, Hooper   +2 more
openaire   +2 more sources