Results 181 to 190 of about 18,160 (210)

Elimination of Antibiotic-Resistant Plasmids by Quinolone Antibiotics

Chemotherapy, 2009
Of 7 plasmids we tested, the plasmid pORF2 was eliminated in vitro with the most efficiency by treatment with subinhibitory concentrations of novobiocin, coumermycin and 10 quinolones. It showed a cure rate of 43% by enoxacin; 12% by novobiocin, pefloxacin, ciprofloxacin and CI-934; 7% by coumermycin and ofloxacin; 9% by amifloxacin; and 4% by AM-833 ...
K P, Fu, M E, Grace, C L, Hsiao, P P, Hung   +3 more
openaire   +2 more sources

Complete nucleotide sequence of a quinolone resistance gene (qnrS2) carrying plasmid of Aeromonas hydrophila isolated from fish

Plasmid, 2011
Aeromonas hydrophila strain AO1 isolated from an infected fish was found to be resistant to several quinolones. A plasmid isolated from the strain AO1, termed pBRST7.6, was cloned and sequenced and shown to be 7621 bp in length with a GC content of 60%.
Tanmay Majumdar, Bhabatosh Das, Rupak K Bhadra   +2 more
exaly   +2 more sources

Elimination of plasmids from Enterobacteriaceae by 4-quinolone derivatives

Journal of Antimicrobial Chemotherapy, 1986
Twelve 4-quinolones (cinoxacin, ciprofloxacin, enoxacin, flumequin, nalidixic acid, norfloxacin, oxolinic acid, pefloxacin, pipemidic acid, rosoxacin, and piromidic and beta-hydroxypiromidic acids) and novobiocin, were used at subinhibitory concentrations to eliminate from Escherichia coli 11 antibiotic resistance plasmids belonging to different ...
Y, Michel-Briand, V, Uccelli, J M, Laporte, P, Plesiat   +3 more
openaire   +2 more sources

Ornamental fish as a source of plasmid-mediated quinolone resistance genes and antibiotic resistance plasmids

Veterinary Microbiology, 2014
Growing ornamental fish industry is associated with public health concerns including extensive antibiotic use accompanied by increasing antibiotic resistance. The aim of this study was to analyze Aeromonas isolates from imported tropical ornamental fish and coldwater koi carps bred in the Czech Republic to assess the potential risk of ornamental fish ...
Hana, Dobiasova, Iva, Kutilova, Veronika, Piackova, Tomas, Vesely, Alois, Cizek, Monika, Dolejska   +5 more
openaire   +2 more sources

[Mechanisms of plasmid-mediated resistance to quinolones].

Enfermedades infecciosas y microbiologia clinica, 2005
Quinolone resistance is caused mainly by chromosomal mutations in gram negative bacteria. In 1998, plasmid-mediated resistance to quinolones in clinical isolates was first reported in a Klebsiella pneumoniae strain. Locus qnr (quinolone resistance) was responsible of the quinolone resistance in this plasmid.
openaire   +2 more sources

Study of Plasmid-Mediated Quinolone Resistance in Bacteria

2017
Plasmid-mediated quinolone resistance (PMQR) involves genes for proteins that protect the quinolone targets, an enzyme that inactivates certain quinolones as well as aminoglycosides, and pumps that efflux quinolones. Quinolone susceptibility is reduced by these mechanisms but not to the level of clinical resistance unless chromosomal mutations are also
openaire   +2 more sources

Quinolone resistance in bacteria: emphasis on plasmid-mediated mechanisms

International Journal of Antimicrobial Agents, 2005
Bacterial resistance to quinolones/fluoroquinolones has emerged rapidly and such resistance has traditionally been attributed to the chromosomally mediated mechanisms that alter the quinolone targets (i.e. DNA gyrase and topoisomerase IV) and/or overproduce multidrug resistance efflux pumps.
openaire   +2 more sources

Plasmid "curing" by some recently synthetized 4-quinolone compounds.

Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988
Nalidixic acid and two recently synthetized 4-quinolones eliminated F'lac and R-plasmids from E. coli at concentrations of one half or one quarter of the minimum inhibitory concentration (MIC). Two of the three plasmids tested were cured by all derivatives, although with different frequencies.
SELAN, Laura, SCAZZOCCHIO, Francesca, B. Oliva, S. Schippa, N. Allocati, RENZINI, Giulio   +5 more
openaire   +3 more sources

Plasmid ecology and tbe elimination of plasmids by 4-quinolones

Journal of Antimicrobial Chemotherapy, 1987
D J, Platt, A C, Black
openaire   +2 more sources

[Inhibition of the maintenance and transfer of antibiotic-resistance plasmids by quinolones].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1986
The role of quinolones in the maintenance and transfer of antibiotic resistance plasmids was investigated. Curing effect of eleven quinolones, at subinhibitory concentrations, was studied on Escherichia coli strains harbouring ten plasmids belonging to different incompatibility groups.
V, Uccelli, J M, Laporte, Y, Michel-Briand   +2 more
openaire   +1 more source