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Fitness Costs of Plasmids: a Limit to Plasmid Transmission [PDF]
Microbiology Spectrum, 2017 ABSTRACT Plasmids mediate the horizontal transmission of genetic information between bacteria, facilitating their adaptation to multiple environmental conditions. An especially important example of the ability of plasmids to catalyze bacterial adaptation and evolution is their instrumental role in the global spread of antibiotic resistance ...
San Millan, A, Maclean, R
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Microbiology and Molecular Biology Reviews, 2010 SUMMARYPlasmids are key vectors of horizontal gene transfer and essential genetic engineering tools. They code for genes involved in many aspects of microbial biology, including detoxication, virulence, ecological interactions, and antibiotic resistance.
Smillie, C. +4 more
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Frontiers in Microbiology, 2023 BackgroundVIM metallo-β-lactamases are enzymes characterized by the ability to hydrolyze all β-lactams. Usually, blaVIM-like genes are carried by class 1 integrons.
Ibrahim Bitar +15 more
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Plasmid, 2023 Plasmids are universally present in bacteria and play key roles in the dissemination of genes such as antibiotic resistance determinants. Major concepts in Plasmid Biology derive from the efforts to classify plasmids. Here, we review the main plasmid classification systems, starting by phenotype-based methods, such as fertility inhibition and ...
Garcillán-Barcia, M. Pilar +2 more
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Frontiers in Microbiology, 2021 Of the seven currently known botulinum neurotoxin-producing species of Clostridium, C. parabotulinum, or C. botulinum Group I, is the species associated with the majority of human botulism cases worldwide.
Theresa J. Smith +10 more
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Phage-Plasmids Spread Antibiotic Resistance Genes through Infection and Lysogenic Conversion
bioRxiv, 2022 The dissemination of antimicrobial resistance is a major threat to global health. Here, we show that a group of temperate bacterial viruses (phages), termed phage-plasmids, commonly encode different and multiple types of resistance genes of high clinical
E. Pfeifer, R. Bonnin, E. Rocha
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Multiple pathways of plasmid DNA transfer in Helicobacter pylori [PDF]
, 2012 Many Helicobacter pylori (Hp) strains carry cryptic plasmids of different size and gene content, the function of which is not well understood. A subgroup of these plasmids (e.g.
Benghezal, Mohammed +5 more
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Antibiotics, 2023 Antibiotic-resistance gene elements (ARGEs) such as antibiotic-resistance genes (ARGs), integrons, and plasmids are key to the spread of antimicrobial resistance (AMR) in marine environments.
Hanan A. Al-Sarawi +5 more
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Plasmid-to-plasmid recombination in Haemophilus influenzae [PDF]
Journal of Bacteriology, 1986 No recombination between plasmids was observed after conjugal transfer of a plasmid into a cell carrying another plasmid. Two types of such recombination took place after transformation, one type being Rec+ dependent and suggesting a preferred site of recombination. The other much rarer type was at least partially Rec+ independent.
Jane K. Setlow, Meenakshi Balganesh
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Emerging Microbes and Infections, 2020 The incidence and transmission of Klebsiella pneumoniae carbapenemase (KPC) producing plasmids have been well documented. However, the evolutionary dynamics of KPC plasmids and their fitness costs are not well characterized.
Xiaoting Hua +6 more
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