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Fitness Costs of Plasmids: a Limit to Plasmid Transmission [PDF]

open access: yesMicrobiology Spectrum, 2017
ABSTRACT Plasmids mediate the horizontal transmission of genetic information between bacteria, facilitating their adaptation to multiple environmental conditions. An especially important example of the ability of plasmids to catalyze bacterial adaptation and evolution is their instrumental role in the global spread of antibiotic resistance ...
San Millan, A, Maclean, R
openaire   +4 more sources

Mobility of Plasmids [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2010
SUMMARYPlasmids are key vectors of horizontal gene transfer and essential genetic engineering tools. They code for genes involved in many aspects of microbial biology, including detoxication, virulence, ecological interactions, and antibiotic resistance.
Smillie, C.   +4 more
openaire   +8 more sources

Plasmid classifications

open access: yesPlasmid, 2023
Plasmids are universally present in bacteria and play key roles in the dissemination of genes such as antibiotic resistance determinants. Major concepts in Plasmid Biology derive from the efforts to classify plasmids. Here, we review the main plasmid classification systems, starting by phenotype-based methods, such as fertility inhibition and ...
Garcillán-Barcia, M. Pilar   +2 more
openaire   +3 more sources

Plasmid-to-plasmid recombination in Haemophilus influenzae [PDF]

open access: yesJournal of Bacteriology, 1986
No recombination between plasmids was observed after conjugal transfer of a plasmid into a cell carrying another plasmid. Two types of such recombination took place after transformation, one type being Rec+ dependent and suggesting a preferred site of recombination. The other much rarer type was at least partially Rec+ independent.
Jane K. Setlow, Meenakshi Balganesh
openaire   +3 more sources

Bacteriophages limit the existence conditions for conjugative plasmids [PDF]

open access: yes, 2015
Bacteriophages are a major cause of bacterial mortality and impose strong selection on natural bacterial populations, yet their effects on the dynamics of conjugative plasmids have rarely been tested.
Brockhurst, Michael A.   +7 more
core   +5 more sources

The distribution of plasmids that carry virulence and resistance genes in Staphylococcus aureus is lineage associated. [PDF]

open access: yes, 2012
BACKGROUND: Staphylococcus aureus is major human and animal pathogen. Plasmids often carry resistance genes and virulence genes that can disseminate through S. aureus populations by horizontal gene transfer (HGT) mechanisms. Sequences of S.
Lindsay, JA, McCarthy, AJ
core   +2 more sources

Plasmids of corynebacteria [PDF]

open access: yesFEMS Microbiology Letters, 1999
Corynebacteria are pleomorphic, asporogenous, Gram-positive bacteria. Included in this group are nonpathogenic soil corynebacteria, which are widely used for the industrial production of amino acids and detergents, and in biotransformation of steroids. Other members of this group are plant and animal pathogens.
Niharika Nath, J. K. Deb
openaire   +3 more sources

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae [PDF]

open access: yes, 2015
OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England.
Alexander W. Tucker   +17 more
core   +3 more sources

Iteron Plasmids

open access: yesMicrobiology Spectrum, 2014
ABSTRACT Iteron-containing plasmids are model systems for studying the metabolism of extrachromosomal genetic elements in bacterial cells. Here we describe the current knowledge and understanding of the structure of iteron-containing replicons, the structure of the iteron plasmid encoded replication initiation proteins, and the molecular ...
Igor, Konieczny   +3 more
openaire   +2 more sources

Reporter constructs with low background activity utilizing the cat gene [PDF]

open access: yes, 1992
Reporter plasmids utilizing the cat gene for the analysis of promoter and enhancer sequences in vertebrate cells, were constructed. These plasmids minimize the background of transcription derived from cryptic promoters or cryptic regulatory elements ...
Andrea Schmidt   +11 more
core   +1 more source

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