Results 41 to 50 of about 680,206 (303)

Recovering Escherichia coli Plasmids in the Absence of Long-Read Sequencing Data

Microorganisms, 2021
The incidence of infections caused by multidrug-resistant E. coli strains has risen in the past years. Antibiotic resistance in E. coli is often mediated by acquisition and maintenance of plasmids. The study of E.
Julian A. Paganini, Nienke L. Plantinga, Sergio Arredondo-Alonso, Rob J. L. Willems, Anita C. Schürch   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Antibiotic resistance plasmids in Enterobacteriaceae isolated from fresh produce in northern Germany

Microbiology Spectrum
In this study, the genomes of 22 Enterobacteriaceae isolates from fresh produce and herbs obtained from retail markets in northern Germany were completely sequenced with MiSeq short-read and MinION long-read sequencing and assembled using a Unicycler ...
Maria Stein, Erik Brinks, Jannike Loop, Diana Habermann, Gyu-Sung Cho, Charles M. A. P. Franz   +5 more
doaj   +1 more source

Plasmids of Clostridioides difficile [PDF]

, 2022
Plasmids are ubiquitous in the bacterial world. In many microorganisms, plasmids have been implicated in important aspects of bacterial physiology and contribute to horizontal gene transfer.
Roseboom, A.M., Corver, J., Smits, W.K., Anna Maria Roseboom, Jeroen Corver, Wiep Klaas Smits   +5 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Plasmids.

, 2015
Plasmids.
Muneyoshi Kanai (756857), Feifei Yu (756853), Ryoko Hamada (756858), Yuko Imamura (271976), Masahiro Sato (15942), Masashi Yukawa (10097), Misaki Nakamura (756854), Yuhki Chihara (756855), Masaru Ueno (564135), Eiko Tsuchiya (756859), Kyo Okane (756856)   +10 more
core   +3 more sources

Diversity of mobile genetic elements in carbapenem-resistant Enterobacterales isolated from the intensive care units of a tertiary care hospital in Northeast India

Frontiers in Microbiology
IntroductionMobile genetic elements (MGEs) play a crucial role in the spread of carbapenem resistance. A study was undertaken to characterize MGEs and evaluate their contribution to the spread of carbapenem resistance in Escherichia coli and Klebsiella ...
Shravani Mitra, Sharmi Naha, Joy Chakraborty, Subhadeep De, Harpreet Kaur, Tapan Majumdar, Sulagna Basu   +6 more
doaj   +1 more source

Enterococcus faecalis an Emerging Microbial Menace in Dentistry-An Insight into the In-Silico Detection of Drug Resistant Genes and Its Protein Diversity [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Antimicrobial drug resistance is evolving as a serious threat to mankind due to indiscriminate use of antibiotics and lack of awareness about the mechanisms involved in drug resistance.
Vijayashree J Priyadharsini, AS Smilinegirija, A Paramasivam   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Characterization of Four Multidrug Resistance Plasmids Captured from the Sediments of an Urban Coastal Wetland

Frontiers in Microbiology, 2017
Self-transmissible and mobilizable plasmids contribute to the emergence and spread of multidrug-resistant bacteria by enabling the horizontal transfer of acquired antibiotic resistance.
Ryan T. Botts, Brooke A. Apffel, C. J. Walters, Kelly E. Davidson, Ryan S. Echols, Michael R. Geiger, Victoria L. Guzman, Victoria S. Haase, Michal A. Montana, Chip A. La Chat, Jenna A. Mielke, Kelly L. Mullen, Cierra C. Virtue, Celeste J. Brown, Eva M. Top, David E. Cummings   +15 more
doaj   +1 more source