Results 41 to 50 of about 645,874 (304)

Recovering Escherichia coli Plasmids in the Absence of Long-Read Sequencing Data

Microorganisms, 2021
The incidence of infections caused by multidrug-resistant E. coli strains has risen in the past years. Antibiotic resistance in E. coli is often mediated by acquisition and maintenance of plasmids. The study of E.
Julian A. Paganini, Nienke L. Plantinga, Sergio Arredondo-Alonso, Rob J. L. Willems, Anita C. Schürch   +4 more
doaj   +1 more source

Multiple pathways of plasmid DNA transfer in Helicobacter pylori [PDF]

, 2012
Many Helicobacter pylori (Hp) strains carry cryptic plasmids of different size and gene content, the function of which is not well understood. A subgroup of these plasmids (e.g.
Haas, Rainer, Rainer Haas, Lea Holsten (133951), Wolfgang Fischer (133965), Holsten, Lea, Stefanie Rohrer (133947), Rohrer, Stefanie, Rainer Haas (81562), Weiss, Evelyn, Lea Holsten, Mohammed Benghezal, Evelyn Weiss (133955), Mohammed Benghezal (133961), Stefanie Rohrer, Wolfgang Fischer, Benghezal, Mohammed, Evelyn Weiss, Fischer, Wolfgang   +17 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Plasmids.

, 2014
aSee Materials and Methods section for details of construction. All plasmids are CEN (single copy) unless otherwise indicated with “2-micron” (high copy).
Michael Reidy (260931), Shankar Shastry (646062), Sue Wickner (549914), Brittany-Lee Roberts (646063), Daniel C. Masison (260932), Ruchika Sharma (646061), Ivan Albino-Flores (646064)   +6 more
core   +3 more sources

Phenotypic and genetic analysis of Klebsiella pneumoniae strains isolated from community-acquired pneumonia patients in Rostov-on-Don in 2021–2023

Инфекция и иммунитет
Introduction. Here, we present a study of 33 Klebsiella pneumoniae strains isolated in Rostov-on-Don in 2021–2023 from patients with community-acquired pneumonia.
Violetta A. Rykova, O. N. Podladchikova, A. S. Anisimova, N. V. Aronova, A. S. Vodopyanov, S. Yu. Temyakova, E. N. Gudueva   +6 more
doaj   +1 more source

Characterization of Four Multidrug Resistance Plasmids Captured from the Sediments of an Urban Coastal Wetland

Frontiers in Microbiology, 2017
Self-transmissible and mobilizable plasmids contribute to the emergence and spread of multidrug-resistant bacteria by enabling the horizontal transfer of acquired antibiotic resistance.
Ryan T. Botts, Brooke A. Apffel, C. J. Walters, Kelly E. Davidson, Ryan S. Echols, Michael R. Geiger, Victoria L. Guzman, Victoria S. Haase, Michal A. Montana, Chip A. La Chat, Jenna A. Mielke, Kelly L. Mullen, Cierra C. Virtue, Celeste J. Brown, Eva M. Top, David E. Cummings   +15 more
doaj   +1 more source

Enterococcus faecalis an Emerging Microbial Menace in Dentistry-An Insight into the In-Silico Detection of Drug Resistant Genes and Its Protein Diversity [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Antimicrobial drug resistance is evolving as a serious threat to mankind due to indiscriminate use of antibiotics and lack of awareness about the mechanisms involved in drug resistance.
Vijayashree J Priyadharsini, AS Smilinegirija, A Paramasivam   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Role of plasmids in antibiotic resistance in clinical infections and implications for epidemiological surveillance: a review

All Life
The global upsurge in antibiotic resistant bacteria (ARB) is putting immense pressure on healthcare. The spreading of antimicrobial resistance is facilitated by mobile genetic elements, most especially plasmids.
Ayodele Oluwaseun Ajayi, Olajide Joseph Akinjogunla, Adebowale Toba Odeyemi, Akinyomade Oladipo Owolabi   +3 more
doaj   +1 more source