Results 61 to 70 of about 680,206 (303)
MicroorganismsTwo Gram-negative aerobic halophilic bacteria, designated KMM 9989T and KMM 9879, were isolated from a bottom sediment sample of the Okhotsk Sea, Russia. The novel strains grew in 0.5–4% NaCl, at 5–35 °C and pH 5.5–10.0.
Lyudmila Romanenko +5 more
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
AntibioticsBackground: This study investigated the phenotypic and genotypic antibiotic resistance profiles of 50 Lactic Acid Bacteria (LAB) strains—25 Lactiplantibacillus plantarum and 25 Lacticaseibacillus paracasei—isolated from traditional Sardinian fermented ...
Gavino Carboni +5 more
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FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
On the Choice of the Right Plasmid Vector(s) in the Times of Synthetic Biology
Microbial BiotechnologyPlasmid vectors are to this day the fundamental tools in molecular biology, but their selection is often guided by convenience rather than informed choice. This article revisits the architectural and functional features that determine plasmid performance
Víctor deLorenzo +1 more
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Adaptative Potential of the Lactococcus Lactis IL594 Strain Encoded in Its 7 Plasmids [PDF]
, 2011 The extrachromosomal gene pool plays a significant role both in evolution and in the environmental adaptation of bacteria. The L. lactis subsp. lactis IL594 strain contains seven plasmids, named pIL1 to pIL7, and is the parental strain of the plasmid ...
Koryszewska-Bagińska, Anna +5 more
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
MicrobiologyOpenAcinetobacter baumannii is widely recognized as a multidrug‐resistant pathogen, although most public genome datasets are biased toward hospital‐derived isolates. Little is known about A. baumannii isolates from healthy individuals in the community.
Soo‐Sum Lean +6 more
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Infection and Drug Resistance, 2023 Kokab Jabeen,1 Sidrah Saleem,1 Shah Jahan,1 Summiya Nizamudin,2 Faiqa Arshad,1 Zill-e Huma,1 Syed Mohsin Raza,3 Maria Mehmood,1 Muhammad Roman,1 Faiz Ul Haq1 1Department of Microbiology, University of Health Sciences, Lahore, Pakistan; 2Department of ...
Jabeen K +9 more
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