Results 81 to 90 of about 842,970 (314)

Spatiotemporal and genomic analysis of carbapenem resistance elements in Enterobacterales from hospital inpatients and natural water ecosystems of an Irish city

Microbiology Spectrum
Carbapenemase-producing Enterobacterales (CPE) is a diverse group of often multidrug-resistant organisms. Surveillance and control of infections are complicated due to the inter-species spread of carbapenemase-encoding genes (CEGs) on mobile genetic ...
Mark Maguire, Carlos Serna, Natalia Montero Serra, Aneta Kovarova, Louise O’Connor, Niamh Cahill, Brigid Hooban, Niall DeLappe, Wendy Brennan, Genevieve Devane, Martin Cormican, Dearbháile Morris, Simone C. Coughlan, Georgios Miliotis, Bruno Gonzalez-Zorn, Liam P. Burke   +15 more
doaj   +1 more source

Molecular Characterization of Extensively Drug Resistant Salmonella Enterica Serovar Typhi Clinical Isolates from Lahore, Pakistan

Infection and Drug Resistance, 2023
Kokab Jabeen,1 Sidrah Saleem,1 Shah Jahan,1 Summiya Nizamudin,2 Faiqa Arshad,1 Zill-e Huma,1 Syed Mohsin Raza,3 Maria Mehmood,1 Muhammad Roman,1 Faiz Ul Haq1 1Department of Microbiology, University of Health Sciences, Lahore, Pakistan; 2Department of ...
Jabeen K, Saleem S, Jahan S, Nizamudin S, Arshad F, Huma ZE, Raza SM, Mehmood M, Roman M, Haq FU   +9 more
doaj  

The antibiotic sensitivity patterns and plasmid DNA content of gram-negative anaerobic bacteria isolated in Palmerston North, New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Masters in Science at Massey University [PDF]

, 1987
One hundred and seven Gram-negative bacteria, including 65 Bacteroides species, 28 fusobacteria and 14 veillonellae were isolated from 17 oral infections treated in two dental surgeries in Palmerston North.
Mooney, Christopher Allan
core  

Multiple pathways of plasmid DNA transfer in Helicobacter pylori [PDF]

, 2012
Many Helicobacter pylori (Hp) strains carry cryptic plasmids of different size and gene content, the function of which is not well understood. A subgroup of these plasmids (e.g.
Benghezal, Mohammed, Fischer, Wolfgang, Haas, Rainer, Holsten, Lea, Rohrer, Stefanie, Weiss, Evelyn   +5 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Pathological Changes in Respiratory Part of Lungs White Mice with Experimental Plague

Эпидемиология и вакцинопрофилактика, 2015
The paper presents data on changes in the respiratory part of lungs of white mice with experimental plague caused by Yersinia рestis strains with different plasmid composition of Tuva and Gorno-Altaisk natural foci of plague and breeding clones ...
S. A. Vityazeva, T. P. Starovoitova, G. B. Mukhturgin, V. I. Dubrovina, S. V. Balakhonov   +4 more
doaj   +1 more source

Inference of plasmid copy number mean and noise from single cell gene expression data

, 2010
Plasmids are extra-chromosomal DNA molecules which code for their own replication. We previously reported a setup using genes coding for fluorescent proteins of two colors that allowed us, using a simple model, to extract the plasmid copy number noise in
Chatenay, Didier, Ghozzi, Stéphane, Ng, Jérôme Wong, Robert, Jérôme   +3 more
core   +1 more source

Detection of VIM-1-producing Enterobacter cloacae and Salmonella enterica Serovars Infantis and Goldcoast at a breeding pig farm in Germany in 2017 and their molecular relationship to former VIM-1-producing S. Infantis Isolates in German livestock production [PDF]

, 2019
In 2011, VIM-1-producing Salmonella enterica serovar Infantis and Escherichia coli were isolated for the first time in four German livestock farms. In 2015/2016, highly related isolates were identified in German pig production.
Borowiak, Maria, Guenther, Sebastian, Hadziabdic, Sead, Kaesbohrer, Annemarie, Malorny, Burkhard, Projahn, Michaela, Roesler, Uwe [u.v.m.], Roschanski, Nicole, Szabo, Istvan, Tenhagen, Bernd-Alois   +9 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source