Results 101 to 110 of about 672,641 (302)

Brazilian Ironstone Plant Communities as Reservoirs of Culturable Bacteria With Diverse Biotechnological Potential

Frontiers in Microbiology, 2018
Extensive mineral extractivism in the Brazilian Iron Quadrangle (IQ) region has destroyed large areas of land, decimating plant species, and their associated microbiota.
Washington L. Caneschi, Érica B. Felestrino, Natasha P. Fonseca, Morghana M. Villa, Camila G. de C. Lemes, Isabella F. Cordeiro, Renata de A. B. Assis, Angélica B. Sanchez, Izadora T. Vieira, Luciana H. Y. Kamino, Flávio F. do Carmo, Camila C. M. Garcia, Camila C. M. Garcia, Leandro M. Moreira, Leandro M. Moreira   +14 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Replicon-Based Typing of IncI-Complex Plasmids, and Comparative Genomics Analysis of IncIγ/K1 Plasmids

Frontiers in Microbiology, 2019
IncI-complex plasmids can be divided into seven subgroups IncI1, IncI2, IncIγ, IncB/O, IncK1, IncK2, and IncZ. In this study, a replicon-based scheme was proposed for typing IncI-complex plasmids into four separately clustering subgroups IncI2, IncI1/B/O,
Defu Zhang, Defu Zhang, Defu Zhang, Defu Zhang, Yuzong Zhao, Yuzong Zhao, Yuzong Zhao, Yuzong Zhao, Jiao Feng, Lingfei Hu, Xiaoyuan Jiang, Zhe Zhan, Huiying Yang, Wenhui Yang, Bo Gao, Jinglin Wang, Jianrong Li, Jianrong Li, Jianrong Li, Zhe Yin, Dongsheng Zhou   +20 more
doaj   +1 more source

Plasmidity: A Novel Pipeline for Plasmid Sequence Prediction

We have built PLASMIDITY, an automated pipeline to assemble short reads and characterize contigs searching for biologically relevant features for plasmid sequences detection applying machine learning methods, including contig length, multiplicity, circularity, insertion sequence composition, chromosome markers (rRNA, tRNA), plasmid markers (OriV, Rep ...
Rosalia Palomino-Cabrera, Inmaculada Garcia Romero, Miguel A. Valvano, Guillermo H. López-Campos   +3 more
openaire   +5 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Prevalence, Serotyping, Molecular Typing, and Antimicrobial Resistance of Salmonella Isolated From Conventional and Organic Retail Ground Poultry

Frontiers in Microbiology, 2018
Ground poultry is marketed as a healthier alternative to ground beef despite the fact that poultry is a major source of foodborne Salmonella. The objectives of this study were to determine the prevalence of Salmonella in Oklahoma retail ground poultry ...
Ahmed H. Gad, Usama H. Abo-Shama, Usama H. Abo-Shama, Katherine K. Harclerode, Mohamed K. Fakhr   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Plasmids.

, 2012
ts: thermosensitive replication; AmpR: carrying resistance to Ampicillin gene, KanaR; carrying resistance to Kanamycin gene; CamR: carrying resistance to Chloramphenicol. ori: origin of replication; FRT: recombination site for Flipase.
Emmanuelle Bouveret (168415), Sandra Angelini (168410), Laetitia My (168412)   +2 more
core   +2 more sources

Genomic characterization of plasmids harboring blaNDM-1, blaNDM-5, and blaNDM-7 carbapenemase alleles in clinical Klebsiella pneumoniae in Pakistan

Microbiology Spectrum
Klebsiella pneumoniae is notorious for causing healthcare-associated infections, which become more complicated by the acquisition of blaNDM genes via mobile genetic elements.
Muhammad Usman Qamar, Roberto Sierra, Kokab Jabeen, Muhammad Rizwan, Ayesha Rashid, Yumna Fatima Dar, Diego O. Andrey   +6 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source