Results 111 to 120 of about 645,874 (304)

Plasmid diversity of Serratia marcescens and Klebsiella pneumoniae isolates involved in two carbapenem-resistant Enterobacteriaceae outbreaks in a Swiss hospital

Microbiology Spectrum
This study investigates two distinct carbapenemase-producing Enterobacteriaceae outbreaks involving patients and contaminated sink traps at the University Hospital of Lausanne.
Florian Mauffrey, Claire Bertelli, Gilbert Greub, Bruno Grandbastien, Laurence Senn, Dominique S. Blanc   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Plasmids.

, 2012
Plasmids.
Adi Peleg (160360), Simi Koby (160357), Krishna C. Suddala (160366), Mark A. Saper (160377), Karthik Sathiyamoorthy (160368), Austin C. Johnson (160363), Bennett E. Smith (160372), Chen Nadler (160352), Ilan Rosenshine (43243)   +8 more
core   +2 more sources

IncHI1 plasmids, a dynamic link between resistance and pathogenicity

, 2008
Plasmids of incompatibility group (Inc) HI1 are important vectors of antibiotic resistance in both of the major causal agents of enteric fever: Salmonella enterica subspecies enterica serovar Typhi and S. Paratyphi A. In S.
Minh-Duy Phan, John Wain
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

DNA Transactions in Bacteria and Membranes: A Place for the Hfq Protein?

Membranes
DNA metabolism consists of crucial processes occurring in all living cells. These processes include various transactions, such as DNA replication, genetic recombination, transposition, mutagenesis, and DNA repair.
Sylwia Bloch, Richard R. Sinden, Frank Wien, Grzegorz Węgrzyn, Véronique Arluison   +4 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Molecular epidemiology and genetic dynamics of carbapenem-resistant hypervirulent Klebsiella pneumoniae in China

Frontiers in Cellular and Infection Microbiology
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CRhvKP) poses a significant global health threat due to its enhanced virulence and resistance. This study analyzed 5,036 publicly available K.
Xiangchen Li, Xiangchen Li, Xiangchen Li, Sisi Chen, Sisi Chen, Yewei Lu, Yewei Lu, Weifeng Shen, Weifeng Shen, Weixin Wang, Weixin Wang, Junli Gao, Junli Gao, Junshun Gao, Junshun Gao, Pingyang Shao, Pingyang Shao, Zhuxian Zhou   +17 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

On plasmids : studies of plasmid-host and plasmid-plasmid interactions

, 2017
Os plasmídeos são moléculas de DNA de cadeia dupla frequentemente isoladas a partir de populações bacterianas. Os plasmídeos replicam-se no interior das suas células hospedeiras e dependem dos seus mecanismos replicativos. Os plasmídeos podem também codificar vários factores envolvidos neste processo.
openaire   +1 more source