Results 1 to 10 of about 49,276 (295)

The first discovery of Tc1 transposons in yeast [PDF]

open access: yesFrontiers in Microbiology, 2023
BackgroundIdentification of transposons without close homologs is still a difficult task. IS630/Tc1/mariner transposons, classified into a superfamily, are probably the most widespread DNA transposons in nature.
Jia Chang   +10 more
doaj   +3 more sources

Cargo Genes of Tn 7 -Like Transposons Comprise an Enormous Diversity of Defense Systems, Mobile Genetic Elements, and Antibiotic Resistance Genes

open access: yesMBio, 2021
Transposition is a major mechanism of horizontal gene mobility in prokaryotes. However, exploration of the genes mobilized by transposons (cargo) is hampered by the difficulty in delineating integrated transposons from their surrounding genetic context ...
Sean Benler, Guilhem Fauré
exaly   +3 more sources

Heterogeneous Lineages of DNA Transposons Encode a TET/JBP Dioxygenase in Fungi [PDF]

open access: yesBiology
Epigenetic DNA modification is a key component of the defense system against invading nucleic acids such as transposons. TET/JBP dioxygenases oxidize 5-methylcytosine and lead to its replacement by cytosine in mammals.
Kenji K. Kojima
doaj   +2 more sources

Transposons disrupt genomic stability and trigger cancers [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
Transposons (TEs) are genetic elements that can change their positions within genome. They cause transcriptional activation or repression by inserting into regulatory elements of related genes or by modulating epigenetic modifications on regulatory ...
Weixia Dong   +7 more
doaj   +2 more sources

Genetic characterisation of antibiotic resistance transposons Tn6608 and Tn6609 isolated from clinical Pseudomonas strains in Cyprus

open access: yesJournal of Global Antimicrobial Resistance, 2021
: Objectives: Antibiotic therapy for Pseudomonas infections is becoming increasingly difficult. In this study, the transposons from two multidrug-resistant (MDR) clinical Pseudomonas strains containing related transposons responsible for giving rise to ...
Vaheesan Rajabal   +6 more
doaj   +1 more source

Introduction of Plant Transposon Annotation for Beginners

open access: yesBiology, 2023
Transposons are mobile DNA sequences that contribute large fractions of many plant genomes. They provide exclusive resources for tracking gene and genome evolution and for developing molecular tools for basic and applied research.
Dongying Gao
doaj   +1 more source

Evolution of piggyBac Transposons in Apoidea

open access: yesInsects, 2023
In this study, we investigated the presence of piggyBac (PB) transposons in 44 bee genomes from the Apoidea order, which is a superfamily within the Hymenoptera, which includes a large number of bee species crucial for pollination.
Xueyuan Li   +9 more
doaj   +1 more source

Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification. [PDF]

open access: yesPLoS Biology, 2003
Heritable, but reversible, changes in transposable element activity were first observed in maize by Barbara McClintock in the 1950s. More recently, transposon silencing has been associated with DNA methylation, histone H3 lysine-9 methylation (H3mK9 ...
Zachary Lippman   +4 more
doaj   +1 more source

The relationship of lamins with epigenetic factors during aging

open access: yesВавиловский журнал генетики и селекции, 2022
The key factor of genome instability during aging is transposon dysregulation. This may be due to senile changes in the expression of lamins, which epigenetically modulate transposons. Lamins directly physically interact with transposons.
R. N. Mustafin, E. K. Khusnutdinova
doaj   +1 more source

The Landscape of the DNA Transposons in the Genome of the Horezu_LaPeri Strain of Drosophila melanogaster

open access: yesInsects, 2023
Natural transposons (NTs) represent mobile DNA sequences found in both prokaryotic and eukaryotic genomes. Drosophila melanogaster (the fruit fly) is a eukaryotic model organism with NTs standing for about 20% of its genome and has contributed ...
Alexandru Marian Bologa   +3 more
doaj   +1 more source

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