Results 1 to 10 of about 15,993 (160)

Identification and characterization of repetitive extragenic palindromes (REP)-associated tyrosine transposases: implications for REP evolution and dynamics in bacterial genomes [PDF]

BMC Genomics, 2010
Background Bacterial repetitive extragenic palindromes (REPs) compose a distinct group of genomic repeats. They usually occur in high abundance (>100 copies/genome) and are often arranged in composite repetitive structures - bacterial interspersed mosaic
Licha Irena, Huckova Tereza, Nunvar Jaroslav   +2 more
doaj   +4 more sources

Multiple Buster transposons from hAT superfamily displaying transposition activities in mammal cells [PDF]

Synthetic and Systems Biotechnology
TcBuster, a member of the Buster family within the hAT superfamily, has been engineered into an effective gene transfer tool for gene therapy applications.
Zhongxia Guan, Binqing Wang, Bo Gao, Shasha Shi, Saisai Wang, Han Wu, Mohamed Diaby, Cai Chen, Xiaoyan Wang, Chengyi Song   +9 more
doaj   +2 more sources

Archaea express circular isoforms of IS200/IS605-associated ωRNAs [PDF]

Frontiers in Microbiology
Circular RNAs (circRNAs) are RNA molecules with 5′ and 3′ ends covalently ligated. Their functions range from acting as genetic regulators to producing proteins, and they are often expressed in a tissue and condition-specific manner.
Beatriz A. Picinato, Vinícius H. Franceschini-Santos, Lívia S. Zaramela, Ricardo Z. N. Vêncio, Tie Koide   +4 more
doaj   +2 more sources

Cargo Genes of Tn7-Like Transposons Comprise an Enormous Diversity of Defense Systems, Mobile Genetic Elements, and Antibiotic Resistance Genes

mBio, 2021
Transposition is a major mechanism of horizontal gene mobility in prokaryotes. However, exploration of the genes mobilized by transposons (cargo) is hampered by the difficulty in delineating integrated transposons from their surrounding genetic context ...
Sean Benler, Guilhem Faure, Han Altae-Tran, Sergey Shmakov, Feng Zhang, Eugene Koonin   +5 more
doaj   +1 more source

PromA Plasmids Are Instrumental in the Dissemination of Linuron Catabolic Genes Between Different Genera

Frontiers in Microbiology, 2020
PromA plasmids are broad host range (BHR) plasmids, which are often cryptic and hence have an uncertain ecological role. We present three novel PromA γ plasmids which carry genes associated with degradation of the phenylurea herbicide linuron, two of ...
Johannes Werner, Eman Nour, Eman Nour, Boyke Bunk, Cathrin Spröer, Kornelia Smalla, Dirk Springael, Başak Öztürk, Başak Öztürk   +8 more
doaj   +1 more source

The unusual structure of the PiggyMac cysteine-rich domain reveals zinc finger diversity in PiggyBac-related transposases

Mobile DNA, 2021
Background Transposons are mobile genetic elements that colonize genomes and drive their plasticity in all organisms. DNA transposon-encoded transposases bind to the ends of their cognate transposons and catalyze their movement. In some cases, exaptation
Marc Guérineau, Luiza Bessa, Séverine Moriau, Ewen Lescop, François Bontems, Nathalie Mathy, Eric Guittet, Julien Bischerour, Mireille Bétermier, Nelly Morellet   +9 more
doaj   +1 more source

Nuclear importation of Mariner transposases among eukaryotes: motif requirements and homo-protein interactions. [PDF]

PLoS ONE, 2011
Mariner-like elements (MLEs) are widespread transposable elements in animal genomes. They have been divided into at least five sub-families with differing host ranges. We investigated whether the ability of transposases encoded by Mos1, Himar1 and Mcmar1
Marie-Véronique Demattei, Sabah Hedhili, Ludivine Sinzelle, Christophe Bressac, Sophie Casteret, Nathalie Moiré, Jeanne Cambefort, Xavier Thomas, Nicolas Pollet, Pascal Gantet, Yves Bigot   +10 more
doaj   +1 more source

A Review of the Functional Annotations of Important Genes in the AHPND-Causing pVA1 Plasmid

Microorganisms, 2020
Acute hepatopancreatic necrosis disease (AHPND) is a lethal shrimp disease. The pathogenic agent of this disease is a special Vibrio parahaemolyticus strain that contains a pVA1 plasmid. The protein products of two toxin genes in pVA1, pirAvp and pirBvp,
Hao-Ching Wang, Shin-Jen Lin, Arpita Mohapatra, Ramya Kumar, Han-Ching Wang   +4 more
doaj   +1 more source

RAREFAN: A webservice to identify REPINs and RAYTs in bacterial genomes

Peer Community Journal, 2023
Compared to eukaryotes, repetitive sequences are rare in bacterial genomes and usually do not persist for long. Yet, there is at least one class of persistent prokaryotic mobile genetic elements: REPINs.
Fortmann-Grote, Carsten, Irmer, Julia von, Bertels, Frederic   +2 more
doaj   +1 more source

The Happy Hopping of Transposons: The Origins of V(D)J Recombination in Adaptive Immunity

Frontiers in Ecology and Evolution, 2022
Nearly 50% of the human genome is derived from transposable elements (TEs). Though dysregulated transposons are deleterious to humans and can lead to diseases, co-opted transposons play an important role in generating alternative or new DNA sequence ...
Rishi V. Shridharan, Neha Kalakuntla, Narendra Chirmule, Bhavana Tiwari   +3 more
doaj   +1 more source