Results 51 to 60 of about 645,874 (304)

Construction of a recombinant plasmid pSH-G containing the rabies-virus glycoprotein G gene

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
A plasmid named pSH-G was constructed with the rabies-virus G-gene insert. This plasmid was transfected into eukaryotic BHK-21 cells and its stability tested.
P. Carnieli JR, A. M. Ventura, E. L. Durigon   +2 more
doaj   +1 more source

Dutch patients, retail chicken meat and poultry share the same ESBL genes, plasmids and strains

, 2011
Intestinal carriage of extended-spectrum beta-lactamase (ESBL) -producing bacteria in food-producing animals and contamination of retail meat may contribute to increased incidences of infections with ESBL-producing bacteria in humans.
Munckhof, M.P., Van den, Essen-Zandbergen, A., Van, Fluit, A.C., Bonten, M.J.M., Platteel, T., Sande-Bruinsma, N., Van de, Leverstein-van Hall, M.A., Mevius, D.J., Scharinga, J., Cohen Stuart, J., Voets, G.M., Dierikx, C.M.   +11 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Plasmid transmission dynamics and evolution of partner quality in a natural population of Rhizobium leguminosarum

mBio
Many bacterial traits important to host–microbe symbiosis are determined by genes carried on extrachromosomal replicons, such as plasmids, chromids, and integrative and conjugative elements. Multiple such replicons often coexist within a single cell and,
David Vereau Gorbitz, Chase P. Schwarz, John G. McMullen, Mario Cerón-Romero, Rebecca T. Doyle, Jennifer A. Lau, Rachel J. Whitaker, Carin K. Vanderpool, Katy D. Heath   +8 more
doaj   +1 more source

Antimicrobial Resistance Genes, Cassettes, and Plasmids Present in Salmonella enterica Associated With United States Food Animals

Frontiers in Microbiology, 2019
The ability of antimicrobial resistance (AR) to transfer, on mobile genetic elements (MGEs) between bacteria, can cause the rapid establishment of multidrug resistance (MDR) in bacteria from animals, thus creating a foodborne risk to human health.
Elizabeth A. McMillan, Sushim K. Gupta, Laura E. Williams, Thomas Jové, Lari M. Hiott, Tiffanie A. Woodley, John B. Barrett, Charlene R. Jackson, Jamie L. Wasilenko, Mustafa Simmons, Glenn E. Tillman, Michael McClelland, Jonathan G. Frye   +12 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Dynamics of Antimicrobial Resistance and Genomic Epidemiology of Multidrug-Resistant Salmonella enterica Serovar Indiana ST17 from 2006 to 2017 in China

mSystems, 2022
The genetic features of foodborne Salmonella have changed in recent years as multidrug-resistant (MDR) strains have become prevalent among various serovars.
Pengcheng Du, Xiaobin Liu, Yue Liu, Ruichao Li, Xin Lu, Shenghui Cui, Yongning Wu, Séamus Fanning, Li Bai   +8 more
doaj   +1 more source

Plasmid persistence: costs, benefits, and the plasmid paradox [PDF]

Canadian Journal of Microbiology, 2018
Plasmids are extrachromosomal DNA elements that can be found throughout bacteria, as well as in other domains of life. Nonetheless, the evolutionary processes underlying the persistence of plasmids are incompletely understood. Bacterial plasmids may encode genes for traits that are sometimes beneficial to their hosts, such as antimicrobial resistance,
Carroll, Amanda C., Wong, Alex
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Genomic Insights into Marinovum sedimenti sp. nov., Isolated from Okhotsk Sea Bottom Sediments, Suggest Plasmid-Mediated Strain-Specific Motility

Microorganisms
Two Gram-negative aerobic halophilic bacteria, designated KMM 9989T and KMM 9879, were isolated from a bottom sediment sample of the Okhotsk Sea, Russia. The novel strains grew in 0.5–4% NaCl, at 5–35 °C and pH 5.5–10.0.
Lyudmila Romanenko, Viacheslav Eremeev, Evgeniya Bystritskaya, Peter Velansky, Valeriya Kurilenko, Marina Isaeva   +5 more
doaj   +1 more source