Results 51 to 60 of about 672,641 (302)

Recovering Escherichia coli Plasmids in the Absence of Long-Read Sequencing Data

Microorganisms, 2021
The incidence of infections caused by multidrug-resistant E. coli strains has risen in the past years. Antibiotic resistance in E. coli is often mediated by acquisition and maintenance of plasmids. The study of E.
Julian A. Paganini, Nienke L. Plantinga, Sergio Arredondo-Alonso, Rob J. L. Willems, Anita C. Schürch   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Molecular analysis of transferable tetracycline resistance plasmids from Clostridium perfringens [PDF]

, 1985
Conjugative tetracycline resistance plasmids from 15 Clostridium perfringens isolates from piggeries were analyzed by restriction endonuclease digestion and agarose gel electrophoresis. Seven isolates from one farm were found to carry a 47-kilobase pair (
Rood, J.I., Abraham, L.J.
core  

Small multidrug resistance plasmids in Actinobacillus porcitonsillarum [PDF]

, 2008
The complete nucleotide sequences of six Actinobacillus porcitonsillarum plasmids pKMA202 (13.425-kb), pKMA1467 (11.115-kb), pKMA5 (9.549-kb), pIMD50 (8.751-kb), pKMA505 (8.632-kb) and pKMA757 (4.556-kb) and three Actinobacillus pleuropneumoniae plasmids
Sieber, Sandra, Matter, Denise, Rossano, Alexandra, Perreten, Vincent   +3 more
core   +1 more source

Diversity of mobile genetic elements in carbapenem-resistant Enterobacterales isolated from the intensive care units of a tertiary care hospital in Northeast India

Frontiers in Microbiology
IntroductionMobile genetic elements (MGEs) play a crucial role in the spread of carbapenem resistance. A study was undertaken to characterize MGEs and evaluate their contribution to the spread of carbapenem resistance in Escherichia coli and Klebsiella ...
Shravani Mitra, Sharmi Naha, Joy Chakraborty, Subhadeep De, Harpreet Kaur, Tapan Majumdar, Sulagna Basu   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The coevolution of toxin and antitoxin genes drives the dynamics of bacterial addiction complexes and intragenomic conflict [PDF]

, 2012
Bacterial genomes commonly contain 'addiction' gene complexes that code for both a toxin and a corresponding antitoxin. As long as both genes are expressed, cells carrying the complex can remain healthy.
Rankin, Daniel J., Leighton A. Turner, Daniel J. Rankin, Heinemann, Jack A., Brown, Sam P., Sam P. Brown, Turner, Leighton A., Jack A. Heinemann   +7 more
core   +1 more source

Characterization of Four Multidrug Resistance Plasmids Captured from the Sediments of an Urban Coastal Wetland

Frontiers in Microbiology, 2017
Self-transmissible and mobilizable plasmids contribute to the emergence and spread of multidrug-resistant bacteria by enabling the horizontal transfer of acquired antibiotic resistance.
Ryan T. Botts, Brooke A. Apffel, C. J. Walters, Kelly E. Davidson, Ryan S. Echols, Michael R. Geiger, Victoria L. Guzman, Victoria S. Haase, Michal A. Montana, Chip A. La Chat, Jenna A. Mielke, Kelly L. Mullen, Cierra C. Virtue, Celeste J. Brown, Eva M. Top, David E. Cummings   +15 more
doaj   +1 more source

Enterococcus faecalis an Emerging Microbial Menace in Dentistry-An Insight into the In-Silico Detection of Drug Resistant Genes and Its Protein Diversity [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Antimicrobial drug resistance is evolving as a serious threat to mankind due to indiscriminate use of antibiotics and lack of awareness about the mechanisms involved in drug resistance.
Vijayashree J Priyadharsini, AS Smilinegirija, A Paramasivam   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source