Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids
Nature Communications, 2014 Plasmids are important drivers of bacterial evolution, but it is challenging to understand how plasmids persist over the long term because plasmid carriage is costly. Classical models predict that horizontal transfer is necessary for plasmid persistence,
Á. S. Millán +8 more
semanticscholar +1 more source
Infection and Drug Resistance, 2023 Kokab Jabeen,1 Sidrah Saleem,1 Shah Jahan,1 Summiya Nizamudin,2 Faiqa Arshad,1 Zill-e Huma,1 Syed Mohsin Raza,3 Maria Mehmood,1 Muhammad Roman,1 Faiz Ul Haq1 1Department of Microbiology, University of Health Sciences, Lahore, Pakistan; 2Department of ...
Jabeen K +9 more
doaj
The Alliance for Cellular Signaling Plasmid Collection: A Flexible Resource for Protein Localization Studies and Signaling Pathway Analysis [PDF]
, 2007 Cellular responses to inputs that vary both temporally and spatially are determined by complex relationships between the components of cell signaling networks.
Bryan, Heather +28 more
core +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
Inference of plasmid copy number mean and noise from single cell gene expression data
, 2010 Plasmids are extra-chromosomal DNA molecules which code for their own replication. We previously reported a setup using genes coding for fluorescent proteins of two colors that allowed us, using a simple model, to extract the plasmid copy number noise in
Chatenay, Didier +3 more
core +1 more source
Dominance of the Inducible State in Strains of Staphylococcus aureus Containing Two Distinct Penicillinase Plasmids [PDF]
, 1965 M. H. Richmond
openalex +1 more source
FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEBS Open Bio, EarlyView.FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang +5 more
wiley +1 more source
Occurrence of various types of penicillinase plasmid among `hospital' staphylococci [PDF]
, 1967 K. G. H. Dyke, M. H. Richmond
openalex +1 more source
, 2021 Trabajo presentado en la conferencia "Plasmids around the Globe", celebrado en modalidad virtual el 06 de mayo de 2021.
Redondo, Santiago +4 more
openaire +1 more source
Reconsidering plasmid maintenance factors for computational plasmid design
Computational and Structural Biotechnology Journal, 2019 Plasmids are genetic parasites of microorganisms. The genomes of naturally occurring plasmids are expected to be polished via natural selection to achieve long-term persistence in the microbial cell population. However, plasmid genomes are extremely diverse, and the rules governing plasmid genomes are not fully understood.
Hirokazu Yano +4 more
openaire +4 more sources