Gene transfection with human hepatocyte growth factor complementary DNA plasmids attenuates cardiac remodeling after acute myocardial infarction in goat hearts implanted with ventricular assist devices [PDF]
Yukitoshi Shirakawa +6 more
openalex +1 more source
Light Regulates Acinetobacter baumannii Chromosomal and pAB3 Plasmid Genes at 37°C
Mariah S. Squire +3 more
openalex +2 more sources
Plasmidity: A Novel Pipeline for Plasmid Sequence Prediction
We have built PLASMIDITY, an automated pipeline to assemble short reads and characterize contigs searching for biologically relevant features for plasmid sequences detection applying machine learning methods, including contig length, multiplicity, circularity, insertion sequence composition, chromosome markers (rRNA, tRNA), plasmid markers (OriV, Rep ...
Palomino-Cabrera, Rosalia +3 more
openaire +2 more sources
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Maria Teresa Mascellino +2 more
doaj +1 more source
Effects of the pSC101 partition (par) locus onin vivoDNA supercoiling near the plasmid replication origin [PDF]
Deirdre L. Conley, Stanley N. Cohen
openalex +1 more source
Whole Genome Sequencing Reveals Presence of High-Risk Global Clones of Klebsiella pneumoniae Harboring Multiple Antibiotic Resistance Genes in Multiple Plasmids in Mwanza, Tanzania [PDF]
Vitus Silago, Stephen E. Mshana
openalex +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Transient high-level expression of ß-galactosidase after transfection of fibroblasts from GM1 gangliosidosis patients with plasmid DNA [PDF]
Raquel Balestrin +6 more
openalex +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

