Results 181 to 190 of about 899,588 (362)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Preventing plasmid multimer formation in commonly used synthetic biology plasmids [PDF]

Elizabeth Vaisbourd, Anat Bren, Uri Alon, David S. Glass   +3 more
openalex   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Beyond borders: plasmids drive a shared antibiotic resistome in European urban water systems. [PDF]

Microbiome
He W, Yu Z, Wu Z, Olesen AK, Madsen JS, Dechesne A, Smets BF, Nesme J, Sørensen SJ.   +8 more
europepmc   +1 more source

The population dynamics of plasmid-mediated antibiotic resistance in salmonella typhimurium in chickens

, 2002
Claire. Risley
openalex   +2 more sources

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Widespread macrolide resistance among rapidly growing mycobacteria due to plasmids containing erm(55). [PDF]

Sci Rep
Graham CI, Brown-Elliott BA, Gonzalez-Ramirez B, Somayaji K, Melton S, Wuzinski M, Wengenack NL, Wallace RJ, Alexander DC.   +8 more
europepmc   +1 more source

Partition‐associated incompatibility caused by random assortment of pure plasmid clusters [PDF]

, 2005
Gitte Ebersbach, David J. Sherratt, Kenn Gerdes   +2 more
openalex   +1 more source

Plasmid incompatibility [PDF]

Microbiological Reviews, 1987
openaire   +2 more sources