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Xylella fastidiosa (Xf) is a phytopathogenic bacterium with a repertoire of self-replicating genetic elements, including plasmids, pathogenicity islands, and prophages. These elements provide potential avenues for horizontal gene transfer both within and
María Pilar Velasco-Amo +5 more
doaj +1 more source
Analysis of two pheromone-responsive conjugative multiresistance plasmids carrying the novel mobile optrA locus from Enterococcus faecalis [PDF]
Background: The acquired optrA gene, which encodes a ribosomal protection protein of the ABC-F family, can confer cross-resistance to linezolid and florfenicol, posing a serious therapeutic challenge to both human and veterinary medicine.
Chen, Yu-Xia +7 more
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Plasmids are universally present in bacteria and play key roles in the dissemination of genes such as antibiotic resistance determinants. Major concepts in Plasmid Biology derive from the efforts to classify plasmids. Here, we review the main plasmid classification systems, starting by phenotype-based methods, such as fertility inhibition and ...
Garcillán Barcia, María del Pilar +2 more
openaire +4 more sources
Mobile genetic elements (MGEs) are relevant agents in bacterial adaptation and evolutionary diversification. Stable appropriation of these DNA elements depends on host factors, among which are the nucleoid-associated proteins (NAPs).
Simón Beard +12 more
doaj +1 more source
ABSTRACT Iteron-containing plasmids are model systems for studying the metabolism of extrachromosomal genetic elements in bacterial cells. Here we describe the current knowledge and understanding of the structure of iteron-containing replicons, the structure of the iteron plasmid encoded replication initiation proteins, and the molecular ...
Igor, Konieczny +3 more
openaire +2 more sources
Distinct genealogies for plasmids and chromosome [PDF]
An earlier perspective on the diversity of conjugative elements in microbes [1] attempted to provide a broad audience with an introductory overview of the arcane biology of mobile genetic elements and their terminologies. It might well have been entitled
Achtman, Mark, Zhou, Zhemin
core +2 more sources
Vaccination with DNA plasmids expressing Gn coupled to C3d or alphavirus replicons expressing Gn protects mice against rift valley fever virus [PDF]
Background: Rift Valley fever (RVF) is an arthropod-borne viral zoonosis. Rift Valley fever virus (RVFV) is an important biological threat with the potential to spread to new susceptible areas. In addition, it is a potential biowarfare agent. Methodology/
A Jouan +58 more
core +4 more sources
Bacteriophages limit the existence conditions for conjugative plasmids [PDF]
Bacteriophages are a major cause of bacterial mortality and impose strong selection on natural bacterial populations, yet their effects on the dynamics of conjugative plasmids have rarely been tested.
Brockhurst, Michael A. +7 more
core +5 more sources
Salmonella are widely distributed foodborne pathogens and are often associated with food animal products. Colistin resistance mediated by mcr-1 is an increasing threat; however, data on the characteristics of mcr-1-harboring Salmonella among retail foods
Changan Li +6 more
doaj +1 more source
In 2014–2015, the main CTX-M-15- and OXA-48-producing clone in our region was ST15. Recently, K. pneumoniae ST15 isolates co-producing VIM-1 and CTX-M-15 were detected in several hospitals.
Patricia Pérez-Palacios +6 more
doaj +1 more source

