Results 141 to 150 of about 384,388 (342)

Fluctuating Warm and Humid Conditions Differentially Impact Immunity and Development in the Malaria Vector Anopheles stephensi. [PDF]

open access: yesGlob Chang Biol
This study shows that fluctuating warm and humid conditions impact immune defenses, accelerate development, enhance post‐infection survival, and alter gene expression in mosquitoes, with potentially significant implications for their ability to vector malaria.
Lemos-Silva T   +3 more
europepmc   +2 more sources

Detecting signatures of balancing selection to identify targets of anti-parasite immunity.

open access: yes, 2010
Parasite antigen genes might evolve under frequency-dependent immune selection. The distinctive patterns of polymorphism that result can be detected using population genetic methods that test for signatures of balancing selection, allowing genes encoding
Conway, David J, Weedall, Gareth D
core   +1 more source

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

open access: yesNature Communications, 2015
The mechanism of action of artemisinin and its derivatives, the most potent of the anti-malarial drugs, is not completely understood. Here we present an unbiased chemical proteomics analysis to directly explore this mechanism in Plasmodium falciparum. We
Jigang Wang   +19 more
semanticscholar   +1 more source

Subtle stressors—Strong responses. Consistent negative effects of avian blood parasites on phenotypic and demographic traits across songbirds

open access: yesJournal of Animal Ecology, EarlyView.
Avian blood parasites are widespread and often considered benign, yet mounting evidence suggests they subtly impair host traits. This meta‐analysis is timely and necessary to quantify their true impact across systems, challenging assumptions and highlighting overlooked consequences for fitness and population dynamics. Abstract Stressors that subtly yet
Marius Grabow   +5 more
wiley   +1 more source

MALARIA

open access: yesAverrous: Jurnal Kedokteran dan Kesehatan Malikussaleh, 2018
Malaria merupakan salah satu penyakit menular yang masih menjadi masalah kesehatan bagi masyarakat. Ada 2 jenis makhluk yang berperan besar dalam penularan malaria yaitu parasit malaria (yang disebut Plasmodium) dan nyamuk anopheles betina.
Julia Fitriany, Ahmad Sabiq
doaj   +1 more source

Evaluation of two candidate molecules—TCTP and cecropin—on the establishment of Trypanosoma brucei gambiense into the gut of Glossina palpalis gambiensis

open access: yesInsect Science, EarlyView.
This study investigates the potential of enhancing the resistance of Glossina palpalis gambiensis to Trypanosoma brucei gambiense to mitigate the transmission of Human African Trypanosomiasis. We successfully cloned genes encoding proteins of interest in Sodalis strains, resulting in recombinant Sodalis (recSodalis) that were micro‐injected into the L3
François Sougal Ngambia Freitas   +9 more
wiley   +1 more source

Plasmodium TatD-Like DNase Antibodies Blocked Parasite Development in the Mosquito Gut

open access: yesFrontiers in Microbiology, 2018
The TatD-like DNase of Plasmodium species has previously been characterized as a conserved antigen that plays an important role in immune evasion.
Wei Wang   +9 more
doaj   +1 more source

Stress in dipteran insects mass‐reared for sterile insect technique applications

open access: yesInsect Science, EarlyView.
The connections between biotic and abiotic stress affecting mass‐reared dipteran insects and the associated stress and immunological responses. Numbers indicate the order in which the topics are discussed in this review. Abstract Stress may be viewed as the disturbance of homeostasis of an organism.
Caroline K. Mirieri   +3 more
wiley   +1 more source

Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

open access: yesNature, 2017
Elucidation of the evolutionary history and interrelatedness of Plasmodium species that infect humans has been hampered by a lack of genetic information for three human-infective species: P. malariae and two P. ovale species (P. o. curtisi and P.
Gavin G. Rutledge   +21 more
semanticscholar   +1 more source

Polychromophilus spp. (Haemosporida: Plasmodiidae): First Molecular Detection in Bat Flies From Brazilian Bats

open access: yesIntegrative Zoology, EarlyView.
This study identifies Polychromophilus sp. in blood‐feeding flies (Basilia speiseri and Basilia lindolphoi) from Myotis nigricans bats in Brazil, marking the first molecular detection of the parasite in an insect vector in this country. Two haplotypes were identified, both within the Polychromophilus murinus group.
Bruno S. Mathias   +7 more
wiley   +1 more source

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