Results 141 to 150 of about 322,747 (249)
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo +9 more
wiley +1 more source
ABSTRACT Aim Cognitive deficits are commonly reported in patients with sickle cell disease (SCD). Dietary micronutrient intake is a potential modifiable risk factor whose relationship with cognition in SCD patients remains poorly characterised. This study aimed to determine the association between dietary micronutrient intake and cognition among these ...
Albert Dennis Kegya +4 more
wiley +1 more source
Under the Cover of Darkness: A Transcriptomic Exploration of Clubroot During the Night
ABSTRACT Plasmodiophora brassicae (Phytomyxea, Rhizaria) is the etiological agent of clubroot disease, one of the most important diseases of Brassicaceae crops. Alteration of metabolism and hormone homeostasis leads to the formation of tumor‐like galls in the roots of affected plants.
Andrea Garvetto +5 more
wiley +1 more source
Stabilizing Plasmodium falciparum proteins for small molecule drug discovery
Abstract Early‐stage drug discovery relies on the availability of stable protein for reliable biophysical characterization of ligand binding. However, many Plasmodium falciparum proteins are challenging to produce in heterologous systems, which limits their experimental utility.
Marius Amann +3 more
wiley +1 more source
Abstract Metrological variations strongly influence malaria transmission by affecting mosquito breeding and survival. Côte d'Ivoire, located within a tropical climate zone, is particularly vulnerable to metrological variations that can alter disease patterns.
Mawussé Bernice Corinne Akpovo +6 more
wiley +1 more source
Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)
ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk +4 more
wiley +1 more source
People‐centred funding as a catalyst for sustainable imaging infrastructure
Abstract Advanced imaging core facilities are critical pillars of modern life sciences research, providing access to complex technologies, specialised expertise, and training. At the heart of these facilities are Imaging Scientists, whose work spans technology development, operations, training, data stewardship, and community coordination.
Yara Reis +8 more
wiley +1 more source
ABSTRACT Identifying close relatives in wild animal populations is fundamental across many research fields. Genetic estimates of relatedness have expanded rapidly in recent decades, drawing on a range of genetic data types. Here, we review their use and outline opportunities for future studies by combining two complementary approaches.
Annika Freudiger +7 more
wiley +1 more source
Editorial: Advancement in malaria treatment
Sarika Gunjan, Manish Goyal
doaj +1 more source
Ligand decorated nanostructure carrier systems for targeted delivery of antimalarials. [PDF]
Singh K +8 more
europepmc +1 more source

