Results 171 to 180 of about 213,023 (194)

RNAi in Plasmodium

Current Pharmaceutical Design, 2014
RNA interference (RNAi) has quickly proven to be an immensely useful tool for studying gene function and validation of potential drug targets in almost all organisms that possess the required set of proteins of the interference pathway. In protozoan parasites like Plasmodium, Toxoplasma, Entamoeba, Giardia, Trypanosoma, and Leishmania, this set of ...
Mueller, Ann-Kristin, Hammerschmidt-Kamper, Christiane, Kaiser, Annette   +2 more
openaire   +3 more sources

The periodicity of Plasmodium vivax and Plasmodium falciparum in Venezuela

Acta Tropica, 2014
We investigated the periodicity of Plasmodium vivax and P. falciparum incidence in time-series of malaria data (1990-2010) from three endemic regions in Venezuela. In particular, we determined whether disease epidemics were related to local climate variability and regional climate anomalies such as the El Niño Southern Oscillation (ENSO).
María-Eugenia Grillet, Mayida El Souki, Francisco Laguna, José Rafael León   +3 more
openaire   +3 more sources

Molecular karyotyping of the rodent malarias Plasmodium chabaudi, Plasmodium berghei and Plasmodium vinckei

Molecular and Biochemical Parasitology, 1989
The molecular karyotypes of four isolates of Plasmodium chabaudi, three of the subspecies P. chabaudi adami and one P. chabaudi chabaudi, as well as P. berghei and P. vinckei were studied by means of pulsed field gradient (PFG) gel electrophoresis. Each species appears to have 14 chromosomes, ranging in size from approximately 730 kb to greater than ...
Jennifer K. Thompson, Michael Sheppard, David J. Kemp, Andrew M. Lew, Robin F. Anders   +4 more
openaire   +3 more sources

Aminopeptidases from Plasmodium falciparum, Plasmodium chabaudi chabaudi and Plasmodium berghei

Journal of Eukaryotic Microbiology, 1994
ABSTRACT. Using fluorogenic substrates and polyacrylamide gels we detected in cell‐free extracts of Plasmodium falciparum, Plasmodium chabaudi chabaudi and Plasmodium berghei only a single aminopeptidase. A comparative study of the aminopeptidase activity in each extract revealed that the enzymes have similar specificities and kinetics, a near‐neutral
Susan M. O'donovan, Margaret M. Mullally, John Mcnally, Alice Troy, John P. Dalton, Sue-Ann O'callaghan, Helen O'hara, G. Paul Curley   +7 more
openaire   +3 more sources

The pre-erythrocytic development of Plasmodium cynomolgi and Plasmodium vivax

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1948
Summary 1. A description is given of experiments resulting in the discovery of the pre-erythrocytic stages in the life cycles of P. cynomolgi and P. vivax 2. In the case of P. cynomolgi , daily development of the forms commencing from the 5th day of the incubation period to the establishment of the blood infection on the 9th and 10th ...
H.E. Shortt, P.C.C. Garnham
openaire   +3 more sources

Characterisation of the rhoph2 gene of Plasmodium falciparum and Plasmodium yoelii

Molecular and Biochemical Parasitology, 2003
The high molecular mass protein complex (RhopH) in the rhoptries of the malaria parasite consists of three distinct polypeptides with estimated sizes in Plasmodium falciparum of 155kDa (PfRhopH1), 140kDa (PfRhopH2) and 110kDa (PfRhopH3). Using a number of reagents, including a new mAb 4E10 that is specific for the PfRhopH complex, it was shown that the
Terry J. Scott-Finnigan, Anthony A. Holder, Osamu Kaneko, David L. Narum, Helen M. Taylor, Motomi Torii, Takafumi Tsuboi, Irene T. Ling, Steven Howell   +8 more
openaire   +3 more sources

Consecutive Inoculations with Plasmodium Vivax and Plasmodium Falciparum

The American Journal of Tropical Medicine, 1939
Summary During the incubation period, at the time of the acute primary attack, or shortly after recovery from the acute attack, an absence of cross immunity between P. vivax and P. falciparum infections has been shown.
Mark F. Boyd, Choice B. Matthews, S. F. Kitchen   +2 more
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TRANSMISSION OF MIXED PLASMODIUM SPECIES AND PLASMODIUM FALCIPARUM GENOTYPES

The American Journal of Tropical Medicine and Hygiene, 2003
We studied malaria transmission by comparing parasite populations in humans and mosquito vectors at the household level. Blood samples were collected from all inhabitants for microscopic detection of gametocytes and polymerase chain reaction analysis.
Katinka Pålsson, Thomas G. T. Jaenson, Georges Snounou, Ana Paula Arez, Virgílio E. do Rosário, João Pinto   +5 more
openaire   +2 more sources

Plasmodium and mononuclear phagocytes

Microbial Pathogenesis, 2015
Plasmodium, the causative agent of malaria, initially multiplies inside liver cells and then in successive cycles inside erythrocytes, causing the symptoms of the disease. In this review, we discuss interactions between the extracellular and intracellular forms of the Plasmodium parasite and innate immune cells in the mammalian host, with a special ...
Laura Mac-Daniel, Robert Ménard
openaire   +3 more sources

Plasmodium berghei and Plasmodium knowlesi: Serum binding to sporozoites

Experimental Parasitology, 1980
Abstract Plasmodium berghei salivary gland and oocyst sporozoites were examined with fluorescein isothiocyanate (FITC)-lectins to determine if sporozoites had carbohydrate-containing molecules on their surfaces. None of the eight fluorescein isothiocyanate-lectins bound to the sporozoites.
Seymour Schulman, Jerome P. Vanderberg, Joel D. Oppenheim   +2 more
openaire   +3 more sources