Results 21 to 30 of about 459,674 (351)

Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections

Cell Reports, 2020
Summary: Gut microbiota composition is associated with human and rodent Plasmodium infections, yet the mechanism by which gut microbiota affects the severity of malaria remains unknown.
Morgan L. Waide, Rafael Polidoro, Whitney L. Powell, Joshua E. Denny, Justin Kos, David A. Tieri, Corey T. Watson, Nathan W. Schmidt   +7 more
doaj   +1 more source

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. [PDF]

, 2014
Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues.
Borboa, Rachel, Campo, Brice, Chatterjee, Arnab K, Chen, Zhong, Diagana, Thierry T, Gagaring, Kerstin, Glynne, Richard J, Klooster, Els J, Kocken, Clemens HM, Kuhen, Kelli, Leroy, Didier, Luty, Adrian, McNamara, Case W, Nagle, Advait, Plouffe, David M, Remarque, Edmond J, Roland, Jason, Sauerwein, Robert, Thomas, Alan W, van Amsterdam, Sandra M, van den Berg, Alexander, van Gemert, Geert-Jan, Voorberg-van der Wel, Annemarie, Winzeler, Elizabeth A, Yeung, Bryan KS, Zeeman, Anne-Marie   +25 more
core   +1 more source

On Programmed Cell Death in Plasmodium falciparum: Status Quo

Journal of Tropical Medicine, 2012
Conflicting arguments and results exist regarding the occurrence and phenotype of programmed cell death (PCD) in the malaria parasite Plasmodium falciparum.
Dewaldt Engelbrecht, Pierre Marcel Durand, Thérèsa Louise Coetzer   +2 more
doaj   +1 more source

The role of Plasmodium falciparum var genes in malaria in pregnancy [PDF]

, 2004
Sequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected ...
Andrews, Baruch, Beeson, Beeson, Beeson, Brabin, Buffet, Chen, Costa, Creasey, Dorman, Duffy, Duffy, Flick, Freitas-Junior, Fried, Fried, Fried, Fried, Gardner, Jensen, Kyes, Kyes, Lekana Douki, McCormick, McGregor, Menendez, Menendez, Nosten, O'Neil-Dunne, Reeder, Reeder, Ricke, Rowe, Rowe, Salanti, Salanti, Shulman, Smith, Smith, Smith, Smith, Staalsoe, Staalsoe, Steketee, Su, Suguitan, Taylor, Taylor, Walter, Ward, Winter   +51 more
core   +1 more source

Ecological immunology of mosquito-malaria interactions: Of non-natural versus natural model systems and their inferences [PDF]

, 2009
There has been a recent shift in the literature on mosquito/Plasmodium interactions with an increasingly large number of theoretical and experimental studies focusing on their population biology and evolutionary processes.
Tripet, F
core   +1 more source

Molecular Markers of Antimalarial Drug Resistance in Plasmodium falciparum From Kumasi, Ghana, 2023 [PDF]

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Artemisinin partial resistance has emerged in East Africa and is feared to spread across the continent, potentially compromising artemisinin‐based combination treatment. Molecular markers can serve as early warning signals for the development of specific drug resistance.
Albert Dennis Kegya, E. Oppong, Eric Darko, Nana Kwame Ayisi‐Boateng, Richard Odame Phillips, Melina Heinemann, Michael Ramharter, Clement Igiraneza, Jules Ndoli, Frank P. Mockenhaupt, Welmoed van Loon   +10 more
openalex   +2 more sources

A Study on the Effect of N-Acetylcysteine on Acute Kidney Injury due to Falciparum Malaria [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Acute Kidney Injury (AKI) occurs most commonly in Plasmodium falciparum infection. Next to cerebral malaria and anaemia, AKI is the third most common complication of falciparum malaria.
GURUPADA DAS, BIBHU PRASAD BEHERA, PURNA CHANDRA KARUA, RAMA CHANDRA SETHY   +3 more
doaj   +1 more source

Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite Plasmodium cynomolgi during progression into dormancy

eLife, 2018
Relapses of Plasmodium dormant liver hypnozoites compromise malaria eradication efforts. New radical cure drugs are urgently needed, yet the vast gap in knowledge of hypnozoite biology impedes drug discovery.
Nicole L Bertschi, Annemarie Voorberg-van der Wel, Anne-Marie Zeeman, Sven Schuierer, Florian Nigsch, Walter Carbone, Judith Knehr, Devendra K Gupta, Sam O Hofman, Nicole van der Werff, Ivonne Nieuwenhuis, Els Klooster, Bart W Faber, Erika L Flannery, Sebastian A Mikolajczak, Vorada Chuenchob, Binesh Shrestha, Martin Beibel, Tewis Bouwmeester, Niwat Kangwanrangsan, Jetsumon Sattabongkot, Thierry T Diagana, Clemens HM Kocken, Guglielmo Roma   +23 more
doaj   +1 more source

In Silico Studies of Four Compounds of Cecropia obtusifolia against Malaria Parasite

Molecules, 2023
Malaria is a disease that affects many people in the world. In Mexico, malaria remains an active disease in certain regions, particularly in the states of Chiapas and Chihuahua.
Carlos Alberto Lobato-Tapia, Yolotl Moreno-Hernández, Zendy Evelyn Olivo-Vidal   +2 more
doaj   +1 more source

Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. [PDF]

, 2007
BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection.
Anderson, T J C, Carlton, J, Day, N P J, Guthmann, J P, Imwong, M, Kim, J R, Looareesuwan, S, Nair, S, Nandy, A, Nosten, F, Pukrittayakamee, S, Snounou, G, Sudimack, D, Tanomsing, N, White, N J   +14 more
core   +2 more sources