Results 21 to 30 of about 15,032 (50)

Absence of PEXEL-Dependent Protein Export in Plasmodium Liver Stages Cannot Be Restored by Gain of the HSP101 Protein Translocon ATPase

Frontiers in Genetics, 2021
Host cell remodeling is critical for successful Plasmodium replication inside erythrocytes and achieved by targeted export of parasite-encoded proteins. In contrast, during liver infection the malarial parasite appears to avoid protein export, perhaps to
Oriana Kreutzfeld, Oriana Kreutzfeld, Oriana Kreutzfeld, Josephine Grützke, Josephine Grützke, Josephine Grützke, Alyssa Ingmundson, Alyssa Ingmundson, Katja Müller, Katja Müller, Kai Matuschewski, Kai Matuschewski   +11 more
doaj   +1 more source

La mitocondria en el género Plasmodium.

Biomédica: revista del Instituto Nacional de Salud, 2003
La mitocondria en las células eucarióticas juega un papel central en el metabolismo energético. En Plasmodium, la mitocondria se adapta morfológica y fisiológicamente a las condiciones metabólicas de sus hospederos.
César Segura, Silvia Blair
doaj   +1 more source

Avian malaria-mediated population decline of a widespread iconic bird species [PDF]

Royal Society Open Science, 2019
Parasites have the capacity to affect animal populations by modifying host survival, and it is increasingly recognized that infectious disease can negatively impact biodiversity.
Daria Dadam, Robert A. Robinson, Anabel Clements, Will J. Peach, Malcolm Bennett, J. Marcus Rowcliffe, Andrew A. Cunningham   +6 more
doaj   +1 more source

A review on malaria eradication: what hope for Nigeria?

Journal of Applied Sciences and Environmental Management, 2016
Malaria and its transmitting vectors are household names. Malaria which helped Africa from the venomous fangs of colonialism has turned to be the bane of development in tropical countries including Nigeria.
E.C. Amadi
doaj   +1 more source

A small mitochondrial protein present in myzozoans is essential for malaria transmission [PDF]

Open Biology, 2016
Myzozoans (which include dinoflagellates, chromerids and apicomplexans) display notable divergence from their ciliate sister group, including a reduced mitochondrial genome and divergent metabolic processes.
Dennis Klug, Gunnar R. Mair, Friedrich Frischknecht, Ross G. Douglas   +3 more
doaj   +1 more source

Nuevas rutas de permeabilidad en Plasmodium falciparum: consideraciones como blanco farmacológico y avances de los potenciales inhibidores

Actualidades Biológicas, 2021
Con base en la persistencia de los casos de malaria, dados por múltiples razones, entre las cuales se encuentra la resistencia de Plasmodium falciparum a los antimálaricos establecidos para su tratamiento, surge la necesidad de encontrar nuevos ...
Yeison Castañeda-Agudelo, Adriana Pabón-Vidal   +1 more
doaj   +1 more source

Malaria and Early Life Immunity: Competence in Context

Frontiers in Immunology, 2021
Childhood vaccines have been the cornerstone tool of public health over the past century. A major barrier to neonatal vaccination is the “immaturity” of the infant immune system and the inefficiency of conventional vaccine approaches at inducing immunity
Perri C. Callaway, Perri C. Callaway, Lila A. Farrington, Margaret E. Feeney, Margaret E. Feeney   +4 more
doaj   +1 more source

PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial

npj Vaccines
The receptor-binding domain, region II, of the Plasmodium vivax Duffy binding protein (PvDBPII) binds the Duffy antigen on the reticulocyte surface to mediate invasion.
Francisco J. Martinez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M. Hou, Sarah E. Silk, Jordan R. Barrett, Carolyn M. Nielsen, Jenny M. Reimer, Paushali Mukherjee, Virander S. Chauhan, Angela M. Minassian, Simon J. Draper, Chetan E. Chitnis   +17 more
doaj   +1 more source

Structural insights into Plasmodium PPIases

Frontiers in Cellular and Infection Microbiology, 2022
Malaria is one of the most prevalent infectious diseases posing a serious challenge over the years, mainly owing to the emergence of drug-resistant strains, sparking a need to explore and identify novel protein targets.
Sreekanth Rajan, Ho Sup Yoon, Ho Sup Yoon, Ho Sup Yoon   +3 more
doaj   +1 more source

A Plasmodium falciparum protein tyrosine phosphatase inhibitor identified from the ChEMBL‐NTD database blocks parasite growth

FEBS Open Bio, 2021
Post‐translational modifications, especially reversible phosphorylation, are among the most common mechanisms that regulate protein function and biological processes in Plasmodium species. Of the Plasmodium phosphatases, phosphatase of regenerating liver
Rajan Pandey, Priya Gupta, Asif Mohmmed, Pawan Malhotra, Dinesh Gupta   +4 more
doaj   +1 more source