Results 41 to 50 of about 263,948 (264)

Suppression of Plasmodium falciparum by serum collected from a case of Plasmodium vivax infection [PDF]

open access: yes, 2008
Background: It has frequently been reported that Plasmodium vivax suppressed Plasmodium falciparum and ameliorated disease severity in patients infected with these two species simultaneously.
Kimura-Sato, M   +39 more
core   +1 more source

A study of the antimalarial action of Pyronaridine and its accumulation into Plasmodium falciparum [PDF]

open access: yes, 2004
Includes abstract.Includes bibliographical references.Pyronaridine (PND), a hydroxyanilino-benzonaphthyridine derivative and also a structural analogue of chloroquine, was synthesized in China in the 1970s as a result of a search for alternative drugs to
Mtegha, Chikumbusko J
core   +1 more source

Heritability of Plasmodium parasite density in a rural Ugandan community. [PDF]

open access: yes, 2010
Many factors influence variation in Plasmodium infection levels, including parasite/host genetics, immunity, and exposure. Here, we examine the roles of host genetics and exposure in determining parasite density, and test whether effects differ with age.
Pullan, Rachel L   +7 more
core   +1 more source

Analysis of immunogenicity of different protein groups from malaria parasite Plasmodium falciparum [PDF]

open access: yes, 2012
It was observed that pressure of host immune system leads to diversifying selection (which can be measured in terms of pN/pS ratio). In this research we checked whether Plasmodium falciparum proteins containing experimentally evident epitopes from the ...
Krzyczmonik, Katarzyna   +5 more
core   +3 more sources

Plasmodium-helminth coinfection and its sources of heterogeneity across East Africa. [PDF]

open access: yes, 2012
BACKGROUND: Plasmodium-helminth coinfection can have a number of consequences for infected hosts, yet our knowledge of the epidemiology of coinfection across multiple settings is limited.
Pullan, Rachel L   +6 more
core   +1 more source

Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity [PDF]

open access: yes, 2008
<i>Plasmodium falciparum</i> sporozoites that develop and mature inside an <i>Anopheles</i> mosquito initiate a malaria infection in humans.
Lasonder Edwin   +87 more
core   +1 more source

Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase. [PDF]

open access: yes, 2012
Signalling by 3'-5'-cyclic guanosine monophosphate (cGMP) exists in virtually all eukaryotes. In the apicomplexan parasite Plasmodium, the cGMP-dependent protein kinase (PKG) has previously been reported to play a critical role in four key stages of the ...
Baker, David A   +25 more
core   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

open access: yesAdvanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang   +13 more
wiley   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

open access: yesAdvanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin   +18 more
wiley   +1 more source

Identification of proteins targeted by the thioredoxin superfamily in Plasmodium falciparum. [PDF]

open access: yes, 2009
The malarial parasite Plasmodium falciparum possesses a functional thioredoxin and glutathione system comprising the dithiol-containing redox proteins thioredoxin (Trx) and glutaredoxin (Grx), as well as plasmoredoxin (Plrx), which is exclusively found ...
Sturm, Nicole   +23 more
core   +2 more sources

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