Results 51 to 60 of about 319,516 (238)

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.

open access: yes, 2009
Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew   +5 more
core   +1 more source

Effect of a+ -thalassaemia on episodes of fever due to malaria and other causes: a communitybased cohort study in Tanzania [PDF]

open access: yes, 2011
Background It is controversial to what degree a+-thalassaemia protects against episodes of uncomplicated malaria and febrile disease due to infections other than Plasmodium. Methods In Tanzania, in children aged 6-60 months and height-for-age z-score
Baidjoe, A.Y.   +7 more
core   +5 more sources

Plasmodium telomere maintenance: uncovering the Achilles’ heel for novel antimalarials

open access: yesFrontiers in Cellular and Infection Microbiology
This review examines the potential of disrupting telomere maintenance in Plasmodium as a novel antimalarial strategy. Telomeres are repetitive DNA–protein structures located at chromosome termini, where they preserve genome stability and protect against ...
Theophilus N. Wakai   +4 more
doaj   +1 more source

Spleen Infarction in Plasmodium Infection [PDF]

open access: yesLiaquat National Journal of Primary Care
Dear Editor, Malaria is a zoonosis causing public health problems, and more than 600,000 deaths yearly mainly younger; splenic infarction or rupture are rarely described [1- 5].
Vitorino Modesto dos Santos   +2 more
doaj   +1 more source

The NTP generating activity of pyruvate kinase II is critical for apicoplast maintenance in Plasmodium falciparum

open access: yeseLife, 2020
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle.
Russell P Swift   +7 more
doaj   +1 more source

Individual-level factors associated with the risk of acquiring human Plasmodium knowlesi malaria in Malaysia: a case-control study [PDF]

open access: yes, 2017
Background: The emergence of human malaria due to the monkey parasite Plasmodium knowlesi threatens elimination efforts in southeast Asia. Changes in land use are thought to be driving the rise in reported P knowlesi cases, but the role of individual ...
Anstey, Nicholas M.   +10 more
core   +3 more sources

The power of many: when genetics met yeasts and high‐throughput

open access: yesBiological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Post‐Artesunate Delayed Hemolysis: Anything That Can Go Wrong Will Go Wrong—Murphy's Law

open access: yesClinical Case Reports
In patients presenting with post‐malarial anemia following intravenous artesunate treatment, post‐artesunate delayed hemolysis should be considered in the differential diagnosis, even in endemic settings.
Beliza Chemutai   +6 more
doaj   +1 more source

A Cross-Sectional Study of Malarial Patients in District Faisalabad, Pakistan: Frequency of Infection, Species Distribution, and Diagnostic Efficiency Comparison

open access: yesCyprus Journal of Medical Sciences
BACKGROUND/AIMS: Malarial infection, caused by Plasmodium parasites transmitted by female Anopheles mosquito, is still a serious public health concern, especially in endemic areas such as Sub-Saharan Africa and Pakistan. The study aims to investigate the
Rashid Ali   +3 more
doaj   +1 more source

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