Results 21 to 30 of about 258,281 (284)
The plasmodium export element revisited [PDF]
We performed a bioinformatical analysis of protein export elements (PEXEL) in the putative proteome of the malaria parasite Plasmodium falciparum. A protein family-specific conservation of physicochemical residue profiles was found for PEXEL-flanking ...
Florian Schwarte +14 more
core +1 more source
On Programmed Cell Death in Plasmodium falciparum: Status Quo
Conflicting arguments and results exist regarding the occurrence and phenotype of programmed cell death (PCD) in the malaria parasite Plasmodium falciparum.
Dewaldt Engelbrecht +2 more
doaj +1 more source
Plasmodium falciparum is the etiological agent of malaria tropica, the leading cause of death due to a vector-borne infectious disease, claiming 0.5 million lives every year. The single-cell eukaryote undergoes a complex life cycle and is an obligate intracellular parasite of hepatocytes (clinically silent) and erythrocytes (disease causing).
Maier, Alex +3 more
openaire +3 more sources
The role of cGMP signalling in regulating life cycle progression of Plasmodium. [PDF]
The 3'-5'-cyclic guanosine monophosphate (cGMP)-dependent protein kinase (PKG) is the main mediator of cGMP signalling in the malaria parasite. This article reviews the role of PKG in Plasmodium falciparum during gametogenesis and blood stage schizont ...
Baker, David A +2 more
core +1 more source
QSAR Analysis of Natural Lupeol Analogs as Antimalarial agents [PDF]
Malaria is an infectious disease that affects millions of people caused by Plasmodium parasite. The growing Plasmodium resistance underscores existing antimalarial drugs and necessities novel antimalarial drugs with high efficiency. Lupeol is a naturally
Rajathei David Mary
doaj +1 more source
Plasmodium-Host-Plasmodium interactions [PDF]
Plasmodium passage through the skin followed by infection of liver hepatocytes and, later, of blood erythrocytes are natural and sequential steps of Plasmodium life cycle in the mammalian host and should not be seen as independent entities. Importantly, in regions of high malaria transmission, infected individuals are constantly exposed to potential re-
openaire +1 more source
Identification of Protein Markers in Patients Infected with Plasmodium knowlesi, Plasmodium falciparum and Plasmodium vivax [PDF]
Malaria is caused by parasitic protozoans of the genus Plasmodium and is one of the most prevalent infectious diseases in tropical and subtropical regions. For this reason, effective and practical diagnostic methods are urgently needed to control the spread of malaria.
Mu, Alan +3 more
openaire +2 more sources
Cytoadherence and virulence - the case of Plasmodium knowlesi malaria. [PDF]
BACKGROUND: Cytoadherence of infected red blood cells to brain endothelium is causally implicated in malarial coma, one of the severe manifestations of falciparum malaria.
Cox-Singh, J +41 more
core +1 more source
Heritability of Plasmodium parasite density in a rural Ugandan community. [PDF]
Many factors influence variation in Plasmodium infection levels, including parasite/host genetics, immunity, and exposure. Here, we examine the roles of host genetics and exposure in determining parasite density, and test whether effects differ with age.
Pullan, Rachel L +12 more
core +1 more source
A Study on the Effect of N-Acetylcysteine on Acute Kidney Injury due to Falciparum Malaria [PDF]
Introduction: Acute Kidney Injury (AKI) occurs most commonly in Plasmodium falciparum infection. Next to cerebral malaria and anaemia, AKI is the third most common complication of falciparum malaria.
GURUPADA DAS +3 more
doaj +1 more source

