Identification of Protein Markers in Patients Infected with Plasmodium knowlesi, Plasmodium falciparum and Plasmodium vivax [PDF]
Malaria is caused by parasitic protozoans of the genus Plasmodium and is one of the most prevalent infectious diseases in tropical and subtropical regions. For this reason, effective and practical diagnostic methods are urgently needed to control the spread of malaria.
Alan Mu, Ping Bee, Yee Lau, Yeng Chen
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The use of selenocysteine (Sec) as the 21st amino acid in the genetic code has been described in all three major domains of life. However, within eukaryotes, selenoproteins are only known in animals and algae. In this study, we characterized selenoproteomes and Sec insertion systems in protozoan Apicomplexa parasites.
Lobanov, Alexey V. +8 more
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On Programmed Cell Death in Plasmodium falciparum: Status Quo
Conflicting arguments and results exist regarding the occurrence and phenotype of programmed cell death (PCD) in the malaria parasite Plasmodium falciparum.
Dewaldt Engelbrecht +2 more
doaj +1 more source
Genetic diversity of Plasmodium vivax and Plasmodium falciparum in Honduras [PDF]
Abstract Background Understanding the population structure of Plasmodium species through genetic diversity studies can assist in the design of more effective malaria control strategies, particularly in vaccine development.
Lopez Ana +7 more
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Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model [PDF]
Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to artemisinin-based combination therapies.
Baro, Nicholas +14 more
core +1 more source
QSAR Analysis of Natural Lupeol Analogs as Antimalarial agents [PDF]
Malaria is an infectious disease that affects millions of people caused by Plasmodium parasite. The growing Plasmodium resistance underscores existing antimalarial drugs and necessities novel antimalarial drugs with high efficiency. Lupeol is a naturally
Rajathei David Mary
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A Study on the Effect of N-Acetylcysteine on Acute Kidney Injury due to Falciparum Malaria [PDF]
Introduction: Acute Kidney Injury (AKI) occurs most commonly in Plasmodium falciparum infection. Next to cerebral malaria and anaemia, AKI is the third most common complication of falciparum malaria.
GURUPADA DAS +3 more
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Synthesis, Characterization, and Anti-Plasmodium falciparum Activity of a New Copper(II) Complex Containing 2-(Tert-Butoxy)-6-(1H-imidazol-1-yl)pyridine. [PDF]
The graphical abstract illustrates the formation of a Cu(II) complex from azole‐based ligand, highlighting metal–ligand synergy. The resulting coordination compound acts as a bioactive entity against Plasmodium, where metal coordination enhances antiparasitic activity, outperforming the free ligand and demonstrating its potential as an antimalarial ...
Patiño-Cubides A +6 more
europepmc +2 more sources
Glucocorticoid dysfunction in children with severe malaria
IntroductionMalaria remains a widespread health problem with a huge burden. Severe or complicated malaria is highly lethal and encompasses a variety of pathological processes, including immune activation, inflammation, and dysmetabolism.
Leen Vandermosten +12 more
doaj +1 more source
Plasmodium-Host-Plasmodium interactions [PDF]
Plasmodium passage through the skin followed by infection of liver hepatocytes and, later, of blood erythrocytes are natural and sequential steps of Plasmodium life cycle in the mammalian host and should not be seen as independent entities. Importantly, in regions of high malaria transmission, infected individuals are constantly exposed to potential re-
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