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Interferon Induced by Plasmodium berghei
Science, 1968An inhibitor of virus is demonstrable in the serums of mice infected with Plasmodium berghei . The titer of the inhibitor, detectable within 10 hours after injection of parasitized blood, increases rapidly until 30 to 40 hours when it levels off or decreases slightly before reaching a plateau.
Kun-Yen Huang +2 more
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Enzyme variation in Plasmodium berghei
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970Abstract 10 strains of P. berghei representing 4 subspecies—P.b. berghei, P.b. yoelii, P.b. killicki and a “P. berghei-like” parasite from Nigeria were used in this study. The electrophoretic band patterns of 4 enzymes—glucose phosphate isomerase, adenylate kinase, 6-phosphogluconate dehydrogenase and malate dehydrogenase were examined in all strains.
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Plasmodium berghei: Energy metabolism of sporozoites
Experimental Parasitology, 1978Abstract The energy metabolism of Plasmodium berghei sporozoites was studied by using their motility as an indicator of energy production and consumption. Sporozoites suspended in medium without sugars or amino acids ceased to move. Motility was restored by the addition of any of several sugars or amino acids to the medium. Inhibition of sporozoite
Jerome P. Vanderberg, Stephen R. Mack
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Plasmodium berghei Infections in Thymectomized Rats
Nature, 1968THE course of P. berghei infections in the rat has been described many times1–4. Young rats, up to about 8 weeks old, usually die with a fulminating acute parasitaemia and severe anaemia. On the other hand, most adult rats develop immunity and almost completely clear the blood stream of parasites soon after the peak parasitaemia.
A. C. Allison, I. N. Brown, R. B. Taylor
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Characterization of Plasmodium berghei glutathione synthetase
Parasitology International, 2011Plasmodium berghei contained 0.454±0.031 U/mg of glutathione synthetyase (GS). GS was purified using solid ammonium sulfate and Sephadex G-200 from P. berghei infected mouse erythrocytes. SDS-PAGE showed purified GS as a single band protein of 70 kDa and its Km for γ-glutamylcysteine, glycine and ATP being 0.33 mM, 8.3 mM and 0.43 mM respectively with ...
H. S. Banyal, S.K. Sharma
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Plasmodium berghei: The in Vitro immune response
Experimental Parasitology, 1981Abstract Following primary in vitro Stimulation by Plasmodium berghei, IgM titers by the indirect fluorescent antibody test (IFAT) were negative in in vitro reconstituted syngeneic mouse spleen cultures containing T cells and macrophages, or B cells and macrophages, or macrophages alone, but IgM titers of 1:20 were obtained from cultures containing B
Shong Wan Norby, Nelda E. Alger
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Adoptive Transfer of Immunity to Plasmodium berghei
The Journal of Protozoology, 1969SYNOPSIS. Immunity to P. berghei in rats was transferred adoptively with spleen cells but not with bone marrow cells, thymus cells, peripheral lymph node cells or thoracic duct lymphocytes from immune donors. The parasite multiplies at the same rate in control and protected rats but when about 10% of host red cells are infected the number of infected ...
J. A. Roberts, P. Tracey-Patte
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A marker epitope of attenuated Plasmodium berghei
Parasitology Research, 1988Plasmodium berghei XAT is an irradiation-induced, permanent attenuated derivative from high-virulence P. berghei NK65. Monoclonal antibodies against XAT were developed. By immunofluorescence screening, one monoclonal antibody was identified that was reactive with XAT at the schizont stage but not with NK65 nor with any other stage of intra-erythrocytic
T. Takagi +4 more
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Plasmodium berghei: T cell-dependent autoimmunity
Experimental Parasitology, 1980Abstract Plasmodium berghei infection in euthymic mice induced the formation of smooth muscle autoantibodies (SMA) persisting in cured immune mice. Antinuclear antibodies (ANA) were found in challenged hyperimmune mice, but not in acutely infected mice. The autoantibodies were not detected in infected and cured athymic, nude mice, and are therefore
Lambert G. Poels +3 more
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Plasmodium berghei and Plasmodium knowlesi: Serum binding to sporozoites
Experimental Parasitology, 1980Abstract Plasmodium berghei salivary gland and oocyst sporozoites were examined with fluorescein isothiocyanate (FITC)-lectins to determine if sporozoites had carbohydrate-containing molecules on their surfaces. None of the eight fluorescein isothiocyanate-lectins bound to the sporozoites.
Seymour Schulman +2 more
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