Results 1 to 10 of about 170,206 (238)

Recent advances in malaria genomics and epigenomics [PDF]

open access: yes, 2016
Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian   +2 more
core   +1 more source

Plasmodium falciparum [PDF]

open access: yesEmerging Topics in Life Sciences, 2017
Plasmodium falciparum is a protozoan parasite that causes the most severe form of human malaria. Five other Plasmodium species can also infect humans — P. vivax, P. malariae, P. ovale curtisi, P. ovale wallikeri and P. knowlesi — but P. falciparum is the most prevalent Plasmodium species in the African region, where 90% of all malaria occurs, and it is
openaire   +2 more sources

Plasmodium falciparum infection and the risk of anemia in school children

open access: yesUniversa Medicina, 2015
BACKGROUND According to the World Health Organization, malaria is the major cause of death from tropical infections in children and pregnant women. Severe anemia is a common complication of malaria, particularly malaria caused by Plasmodium falciparum ...
Suriyani Tan   +2 more
doaj   +1 more source

Genetic Analysis and Species Specific Amplification of the Artemisinin Resistance-Associated Kelch Propeller Domain in P. falciparum and P. vivax. [PDF]

open access: yesPLoS ONE, 2015
Plasmodium falciparum resistance to artemisinin has emerged in the Greater Mekong Subregion and now poses a threat to malaria control and prevention. Recent work has identified mutations in the kelch propeller domain of the P.
Eldin Talundzic   +7 more
doaj   +1 more source

Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model [PDF]

open access: yes, 2016
Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to artemisinin-based combination therapies.
Baro, Nicholas   +14 more
core   +1 more source

Incidence of malarial infection and response to antimalarial drugs at Districts Lower Dir and Swat of Khyber Pakhtunkhwa, Pakistan

open access: yesDialogues in Health, 2022
Malaria is the leading cause of mortality and morbidity all over the world. Several antimalarial drugs are available for the treatment of malaria. The main objective of this study was to investigate the incidence of malarial infection and the use of ...
Nasib Zaman   +8 more
doaj   +1 more source

Klasifikasi Citra Plasmodium Penyebab Penyakit Malaria dalam Sel Darah Merah Manusia dengan Menggunakan Metode Multi Class Support Vector Machine (SVM)

open access: yesIlkom Jurnal Ilmiah, 2016
Malaria adalah penyakit kronis dan akut yang disebabkan oleh protozoa dari jenis Plasmodium. Ada 4 spesies yang utama dari jenis plasmodium yang menyebabkan penyakit malaria pada manusia, yaitu: Plasmodium falciparum, Plasmodium vivax, Plasmodium ...
Nur Ain Banyal   +2 more
doaj   +1 more source

Prevalence of Clinical Artesunate Resistance among Cases of Complicated Malaria in Southern Odisha, India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Drug resistant malaria represents the most challenging health problem worldwide. The major threat to malaria control is the increasing incidence of complicated and drug-resistant cases.
Sindhusuta Das, Sanghamitra Padhi
doaj   +1 more source

In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up. [PDF]

open access: yes, 2004
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28 days or longer that were conducted between 1990 and 2003
Stepniewska, K   +16 more
core   +2 more sources

A Plasmodium falciparum host-targeting motif functions in export during blood stage infection of the rodent malarial parasite Plasmodium berghei. [PDF]

open access: yesPLoS ONE, 2008
Plasmodium falciparum (P. falciparum) secretes hundreds of proteins--including major virulence proteins--into the host erythrocyte. In order to reach the host cytoplasm, most P. falciparum proteins contain an N terminal host-targeting (HT) motif composed
Julia J MacKenzie   +4 more
doaj   +1 more source

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