Results 1 to 10 of about 290,040 (322)

Accuracy of malaria diagnosis by clinical laboratories in Belgium

Malaria Journal, 2019
Background The Belgian Reference Laboratory for Plasmodium offers a free-of-charge reference testing of malaria-positive or doubtful samples to clinical laboratories.
Laura Loomans, Anali Conesa Botella, Agnes D’hondt, Jacob Verschueren, Dorien Van den Bossche, Marjan Van Esbroeck, Jan Jacobs   +6 more
doaj   +1 more source

Plasmodium falciparum biosynthesizes sulfoglycosphingolipids

Molecular and Biochemical Parasitology, 2007
Sulfated glycosphingolipids are present on the surface of a variety of cells. They are active participants in adhesion processes in many systems and appear to be involved in the regulation of cell proliferation, differentiation and other developmental cellular events.
Landoni, Malena, Duschak, Vilma Gladys, Peres, Valnice J., Nonami, Hiroshi, Erra Balsells, Rosa, Katzin, Alejandro M., Couto, Alicia Susana   +6 more
openaire   +4 more sources

Structure and Drug Resistance of the Plasmodium falciparum Transporter PfCRT

Nature, 2019
The emergence and spread of drug-resistant Plasmodium falciparum impedes global efforts to control and eliminate malaria. For decades, treatment of malaria has relied on chloroquine (CQ), a safe and affordable 4-aminoquinoline that was highly effective ...
Jonathan Kim, Yong Zi Tan, Kathryn J. Wicht, S. Erramilli, Satish K. Dhingra, John Okombo, Jérémie Vendôme, Laura M. Hagenah, Sabrina Giacometti, Audrey L. Warren, K. Nosol, P. Roepe, C. Potter, B. Carragher, A. Kossiakoff, M. Quick, D. Fidock, F. Mancia   +17 more
semanticscholar   +1 more source

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants [PDF]

, 2016
Genetic screening using random transposon insertions has been a powerful tool for uncovering biology in prokaryotes, where whole-genome saturating screens have been performed in multiple organisms. In eukaryotes, such screens have proven more problematic,
Adams, John H., Bronner, Iraad F., Jiang, Rays H. Y., Otto, Thomas D., Quail, Michael A., Rayner, Julian C., Udenze, Kenneth, Wang, Chengqi, Zhang, Min   +8 more
core   +1 more source

Plasmodium falciparum infection and the risk of anemia in school children [PDF]

Universa Medicina, 2013
Background According to the World Health Organization, malaria is the major cause of death from tropical infections in children and pregnant women. Severe anemia is a common complication of malaria, particularly malaria caused by Plasmodium falciparum ...
Suriyani Tan, Taniawati Supali, Heri Wibowo   +2 more
doaj  

Molecular identification of Plasmodium species in symptomatic children of Democratic Republic of Congo

Malaria Journal, 2018
Background Worldwide, the highest malaria mortality is due to Plasmodium falciparum infection. However, other species of Plasmodium (Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and Plasmodium knowlesi) can also cause malaria.
Hugo Kavunga-Membo, Gillon Ilombe, Justin Masumu, Junior Matangila, Joël Imponge, Emile Manzambi, Francis Wastenga, Dieudonné Mumba Ngoyi, Jean-Pierre Van Geetruyden, Jean Jacques Muyembe   +9 more
doaj   +1 more source

DNA recovery from used malaria RDT to detect Plasmodium species and to assess Plasmodium falciparum genetic diversity: a pilot study in Madagascar

Malaria Journal, 2022
Background Rapid diagnostic tests (RDT) are widely used for malaria diagnosis in Madagascar, where Plasmodium falciparum is the predominant species. Molecular diagnosis is essential for malaria surveillance, but requires additional blood samples for DNA ...
Voahangy Hanitriniaina I. Andrianaranjaka, Elisabeth Ravaoarisoa, Tovonahary A. Rakotomanga, Fanomezantsoa Ralinoro, Danielle A. Doll Rakoto, Ranjàna H. Randrianarivo, Victor Jeannoda, Arsène Ratsimbasoa   +7 more
doaj   +1 more source

Major subpopulations of Plasmodium falciparum in sub-Saharan Africa

Science, 2019
Ebb and flow of parasite populations The population genetics of the malaria parasite Plasmodium falciparum across Africa is poorly understood but important to know for grasping the risks and dynamics of the spread of drug resistance. Harnessing the power
A. Amambua-Ngwa, L. Amenga-Etego, E. Kamau, R. Amato, A. Ghansah, L. Golassa, M. Randrianarivelojosia, D. Ishengoma, T. Apinjoh, O. Maïga-Ascofaré, B. Andagalu, W. Yavo, M. Bouyou-Akotet, O. Kolapo, Karim Mane, A. Worwui, D. Jeffries, Vikki Simpson, U. d’Alessandro, D. Kwiatkowski, A. Djimde   +20 more
semanticscholar   +1 more source

The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony [PDF]

, 2010
A role for the Plasmodium falciparum cyclic GMP (cGMP)-dependent protein kinase (PfPKG) in gametogenesis in the malaria parasite was elucidated previously. In the present study we examined the role of PfPKG in the asexual blood-stage of the parasite life
Baker, D.A., Dluzewski, A.R., Grainger, M., Holder, A.A., Hopp, C.S., McRobert, L., Sicard, A., Taylor, H.M.   +7 more
core   +1 more source

Evaluation of FRET real-time PCR assay for rapid detection and differentiation of Plasmodium species in returning travellers and migrants

Malaria Journal, 2008
Background A simple real-time PCR assay using one set of primer and probe for rapid, sensitive and quantitative detection of Plasmodium species, with simultaneous differentiation of Plasmodium falciparum from the three other Plasmodium species ...
Pistone Thierry, Receveur Marie-Catherine, Fregeville Frédéric, Melinard Laurence, Boucher Sébastien, Millet Pascal, Safeukui Innocent, Fialon Pierre, Vincendeau Philippe, Fleury Hervé, Malvy Denis   +10 more
doaj   +1 more source