Results 171 to 180 of about 302,576 (367)

Detection and biological assessment of genome structural variation in Plasmodium falciparum

, 2022
Becky A. Miller
openalex   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Cryopreservation of Anopheles gambiae Larvae

Advanced Biology, Volume 10, Issue 1, January 2026.
Advancements in vector control methods have resulted in a rapidly growing collection of critically important mosquito strains necessitating the development of cryopreservation protocols to minimize the risk of genetic drift, cross‐contamination, or catastrophic loss.
Purva Joshi, Zachary Chau, Abby Callahan‐Muller, Vincent O. Nyasembe, Kala Acha, Ellen M. Dotson, Mehmet Toner, Rebecca D. Sandlin   +7 more
wiley   +1 more source

Genome sequence of the human malaria parasite Plasmodium falciparum

Nature, 2002
M. Gardner, N. Hall, E. Fung, O. White, M. Berriman, R. Hyman, J. Carlton, A. Pain, K. Nelson, S. Bowman, I. Paulsen, K. James, J. Eisen, Kim M Rutherford, S. Salzberg, A. Craig, S. Kyes, Man-Suen Chan, V. Nene, S. Shallom, Bernard B. Suh, J. Peterson, Samuel V. Angiuoli, M. Perțea, Jonathan E. Allen, J. Selengut, D. Haft, M. Mather, A. Vaidya, David M. A. Martin, A. Fairlamb, M. Fraunholz, D. Roos, S. Ralph, G. McFadden, L. M. Cummings, G. Subramanian, C. Mungall, J. Venter, D. Carucci, S. Hoffman, C. Newbold, Ronald W. Davis, C. Fraser, B. Barrell   +44 more
semanticscholar   +1 more source

Plasmodium falciparum Genotype Diversity in Artemisinin Derivatives Treatment Failure Patients along the Thai-Myanmar Border [PDF]

, 2014
Kanungnit Congpuong, Thirasak Hoonchaiyapoom, Kornnarin Inorn   +2 more
openalex   +1 more source

PREVALENCE OF PLACENTAL INFECTION WITH PLASMODIUM FALCIPARUM DETECTED BY POLYMERASE CHAIN REACTION AND ASSOCIATED RISK FACTORS IN WOMEN AFTER DELIVERED OUAGADOUGOU (BURKINA FASO)

, 2021
Sawadogo Haffsatou, Adama Zida, Cheikna Zongo, Issiaka Soulama, Sawadogo Patindoilba Marcel, Guiguemde Kiswendsida Thierry, Serme Sindie Samuel, Sangare Lassana Sangare Ibrahim   +7 more
openalex   +2 more sources

Cellular Hallmarks From Volume Electron Microscopy Reveal Developmental Progression of Plasmodium Ookinetes

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This article presents a detailed ultrastructural cell atlas of Plasmodium ookinete development using advanced volume electron microscopy (v) techniques. It defines seven distinct developmental stages, revealing complex organelle interactions and offering new insights into parasite differentiation.
Nedal Darif, Marco Rheinnecker, Kolja Hildenbrand, Thanat Chookajorn, Lilian P. Dorner, Jean‐Karim Hériché, Sara Henriksson, Charlotta Funaya, Franziska Hentzschel, Linda Sandblad, Oliver Billker, Yannick Schwab, Friedrich Frischknecht   +12 more
wiley   +1 more source

Universal Regulation of DNA Polymerase via Photocaged Primer Enables Light‐Start Isothermal Amplification on Demand

Advanced Science, Volume 13, Issue 3, 14 January 2026.
A simple and general photoactivatable approach is developed to regulate DNA polymerase activity, enabling light‐start isothermal amplification on demand. The molecular dynamics simulations reveals that the photocaged primer blocks DNA polymerase activity by inhibiting the conformational change of the polymerase.
Min Qing, Yufan Qin, Zhijin Li, Xiufang Yu, Jianbo Wang, Xiaoqiong Liu, Xin Chen, Chao Yu   +7 more
wiley   +1 more source

Artemisinin resistance in Plasmodium falciparum malaria.

New England Journal of Medicine, 2009
A. Dondorp, F. Nosten, P. Yi, D. Das, A. P. Phyo, J. Tarning, K. Lwin., F. Ariey, Warunee Hanpithakpong, Sue J Lee, P. Ringwald, K. Silamut, M. Imwong, K. Chotivanich, Pharath Lim, T. Herdman, S. An, S. Yeung, P. Singhasivanon, N. Day, N. Lindegårdh, D. Socheat, N. White   +22 more
semanticscholar   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source