Peptides of H. sapiens and P. falciparum that are predicted to bind strongly to HLA-A*24:02 and homologous to a SARS-CoV-2 peptide [PDF]
Aim: This study is looking for a common pathogenicity between SARS-CoV-2 and plasmodium species, in individuals with certain HLA serotypes. Methods: 1-) Tblastx searches of SARS-CoV-2 are performed by limiting searches to plasmodium species that infect human. 2-) Aligned sequences in the respective organisms' proteomes are searched with blastp.
arxiv +1 more source
Significant geographical differences in prevalence of mutations associated with Plasmodium falciparum and Plasmodium vivax drug resistance in two regions from Papua New Guinea [PDF]
Drug resistance remains a major obstacle to malaria treatment and control. It can arise and spread rapidly, and vary substantially even at sub-national level.
Barnadas, Céline+15 more
core +3 more sources
Plasmodium falciparum infection and the risk of anemia in school children
BACKGROUND According to the World Health Organization, malaria is the major cause of death from tropical infections in children and pregnant women. Severe anemia is a common complication of malaria, particularly malaria caused by Plasmodium falciparum ...
Suriyani Tan+2 more
doaj +1 more source
Computational identification of signalling pathways in Plasmodium falciparum [PDF]
Malaria is one of the world’s most common and serious diseases causing death of about 3 million people each year. Its most severe occurrence is caused by the protozoan Plasmodium falciparum.
Adebiyi, E. F.+4 more
core +2 more sources
Malaria adalah penyakit kronis dan akut yang disebabkan oleh protozoa dari jenis Plasmodium. Ada 4 spesies yang utama dari jenis plasmodium yang menyebabkan penyakit malaria pada manusia, yaitu: Plasmodium falciparum, Plasmodium vivax, Plasmodium ...
Nur Ain Banyal+2 more
doaj +1 more source
Prevalence of Clinical Artesunate Resistance among Cases of Complicated Malaria in Southern Odisha, India [PDF]
Introduction: Drug resistant malaria represents the most challenging health problem worldwide. The major threat to malaria control is the increasing incidence of complicated and drug-resistant cases.
Sindhusuta Das, Sanghamitra Padhi
doaj +1 more source
An evolutionary perspective on the kinome of malaria parasites [PDF]
Malaria parasites belong to an ancient lineage that diverged very early from the main branch of eukaryotes. The approximately 90-member plasmodial kinome includes a majority of eukaryotic protein kinases that clearly cluster within the AGC, CMGC, TKL ...
Andrew B. Tobin+6 more
core +1 more source
Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi [PDF]
<b>Background:</b> Described here is the first population genetic study of Plasmodium malariae, the causative agent of quartan malaria. Although not as deadly as Plasmodium falciparum, P.
Alex McConnachie+44 more
core +4 more sources
Background Malaria and helminths share the same geographical distribution in tropical Africa. Studies of the interaction of helminth and malaria co-infection in humans have been few and are mainly epidemiological, with little information on cellular ...
Richard Bwanika+3 more
doaj +1 more source
Recent advances in malaria genomics and epigenomics [PDF]
Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian+2 more
core +1 more source