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Plasmodium falciparum is a protozoan parasite that causes the most severe form of human malaria. Five other Plasmodium species can also infect humans — P. vivax, P. malariae, P. ovale curtisi, P. ovale wallikeri and P. knowlesi — but P. falciparum is the most prevalent Plasmodium species in the African region, where 90% of all malaria occurs, and it is
Catherine J. Merrick
openaire +3 more sources
Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia
Diagnosis and treatment of Plasmodium falciparum infections are required for effective malaria control and are pre-requisites for malaria elimination efforts; hence we need to monitor emergence, evolution and spread of drug- and diagnostics-resistant ...
A. Fola +15 more
semanticscholar +1 more source
A malária é uma doença ainda muito comum. Em 2002, segundo o relatório da OMS havia cerca de 207 milhões de casos, sendo que apenas naquele ano ocorreram 627 mil mortes.
J. Fernandes, Lucas Nishida
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Anopheles stephensi Mosquitoes as Vectors of Plasmodium vivax and falciparum, Horn of Africa, 2019
Anopheles stephensi mosquitoes, efficient vectors in parts of Asia and Africa, were found in 75.3% of water sources surveyed and contributed to 80.9% of wild-caught Anopheles mosquitoes in Awash Sebat Kilo, Ethiopia.
F. Tadesse +36 more
semanticscholar +1 more source
Artemisinin resistance (delayed P. falciparum clearance following artemisinin-based combination therapy), is widespread across Southeast Asia but to date has not been reported in Africa1–4. Here we genotyped the P.
A. Uwimana +17 more
semanticscholar +1 more source
Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria.
Understanding and controlling the spread of antimalarial resistance, particularly to artemisinin and its partner drugs, is a top priority. Plasmodium falciparum parasites resistant to chloroquine, amodiaquine, or piperaquine harbor mutations in the P ...
Kathryn J. Wicht, Sachel Mok, D. Fidock
semanticscholar +1 more source
Background Malaria control efforts are highly skewed towards Plasmodium falciparum while overlooking other Plasmodium species such as P. malariae. A better understanding of the role of Plasmodium species other than P.
Daniel Nguiffo-Nguete +9 more
doaj +1 more source
Recent advances in malaria genomics and epigenomics [PDF]
Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian +2 more
core +1 more source
Characterization of Plasmodium falciparum glutamate dehydrogenase-soluble antigen
The major aim of this study was to characterize a soluble Plasmodium falciparum antigen from the plasma of malaria-infected humans and Plasmodium falciparum culture supernatants, using immunoabsorbent techniques and Western blotting. An Mr 60-kDa protein
A. Rodríguez-Acosta +3 more
doaj +1 more source

