Results 1 to 10 of about 31,601 (161)

Computational vaccine development against protozoa [PDF]

Computational and Structural Biotechnology Journal
Protozoan parasites remain a major global health and economic burden, particularly in low- and middle-income countries. Conventional strategies such as chemotherapy and vector control face growing limitations due to resistance, toxicity, and ...
Omar Hashim, Isabelle Dimier-Poisson
doaj   +2 more sources

Diagnostic potential of a multi-antigen ELISA for feline leishmaniosis [PDF]

Parasites & Vectors
Background Leishmania infantum is a sand fly-transmitted zoonotic protozoan, endemic in the Mediterranean basin and responsible for human, canine (CanL), and feline (FeL) leishmaniosis.
Clara M. Lima, Óscar Felgueiras, Margarida Brito, Mariaelisa Carbonara, Domenico Otranto, Andreia Magalhães, Rui Ferreira, Joana Tavares, Luís Cardoso, Anabela Cordeiro da Silva, Nuno Santarém   +10 more
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Different kinetics of humoral response against individual antigens in the ovine model of Toxoplasma gondii infection and its pathological association [PDF]

Frontiers in Immunology
BackgroundToxoplasma gondii is a globally distributed protozoan parasite with major implications for human and animal health. In sheep, infection can cause reproductive failure and represents an important source of zoonotic transmission through ...
Paula Formigo, Ignacio Gual, Ignacio Gual, Germán J. Cantón, Luisa F. Mendoza Morales, Luisa F. Mendoza Morales, Emiliano Sosa, Agustina Soto Cabrera, Valeria Scioli, Claudia Morsella, Valeria A. Sander, Dadin P. Moore, Dadin P. Moore, Sergio O. Angel, Lucía M. Campero, Marina Clemente   +15 more
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Antibody response induced by structural proteins from Triatoma virus as potential adjuvants in experimental immunisation models [PDF]

Frontiers in Microbiology
IntroductionVirus-Like Particles (VLPs) are viral protein structures widely used as adjuvants in vaccine formulations due to their ability to stimulate the innate immune response, thereby contributing to the activation of adaptive immunity through the ...
Aline Maria Vasconcelos Queiroz, Aline Maria Vasconcelos Queiroz, Annamairlla do Nascimento Oliveira, Annamairlla do Nascimento Oliveira, Alzira Regina Silva de Deus, Alzira Regina Silva de Deus, Ingrid Emiliane Fonseca de Oliveira, Isaías Amâncio dos Santos, Fred Luciano Neves Santos, Paola Alejandra Fiorani Celedon, Diego M. A. Guérin, Ana Rosa Viguera, Marcelo Sousa-Silva, Marcelo Sousa-Silva, Marcelo Sousa-Silva   +14 more
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Plant Expression of Hydrophobin Fused K39 Antigen for Visceral Leishmaniasis Immunodiagnosis

Frontiers in Plant Science, 2021
Visceral leishmaniasis is a Neglected Tropical Disease of high mortality caused by the protozoan Leishmania infantum. Its transmission cycle is complex, and it has in the domestic dog its main reservoir.
Bruno B. Silva, Bruno B. Silva, Eduarda N. F. N. Santos, Eduarda N. F. N. Santos, Lucelina S. Araújo, Arnaldo S. Bezerra, Arnaldo S. Bezerra, Lívia É. C. Marques, Eridan O. P. Tramontina Florean, Maurício F. van Tilburg, Maurício F. van Tilburg, Maria Izabel F. Guedes, Maria Izabel F. Guedes   +12 more
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Concomitant infections, parasites and immune responses. [PDF]

, 2001
Concomitant infections are common in nature and often involve parasites. A number of examples of the interactions between protozoa and viruses, protozoa and bacteria, protozoa and other protozoa, protozoa and helminths, helminths and viruses, helminths ...
Cox, FE
core   +5 more sources

Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia

Nature Communications, 2023
The genomes of most protozoa encode families of variant surface antigens. In some parasitic microorganisms, it has been demonstrated that mutually exclusive changes in the expression of these antigens allow parasites to evade the host’s immune response ...
Albano H. Tenaglia, Lucas A. Luján, Diego N. Ríos, Cecilia R. Molina, Victor Midlej, Paula A. Iribarren, María A. Berazategui, Alessandro Torri, Alicia Saura, Damián O. Peralta, Macarena Rodríguez-Walker, Elmer A. Fernández, Juan P. Petiti, Marianela C. Serradell, Pablo R. Gargantini, Tim Sparwasser, Vanina E. Alvarez, Wanderley de Souza, Hugo D. Luján   +18 more
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Discovery of Antigens and Cellular Mechanisms in the Protozoan Parasite Sarcocystis aucheniae Using Immunoproteomics

Parasitologia, 2023
Sarcocystis aucheniae is a coccidian parasite that produces macroscopic sarcocysts in South American camelid (SAC) muscles and causes a disease known as SAC sarcocystosis.
Sarah Nathaly Wieser, Cecilia Decker-Franco, Paloma de Alba, Sandra Romero, Alejandro Ferrari, Leonhard Schnittger, Mónica Florin-Christensen   +6 more
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Conserved Candidate Antigens and Nanoparticles to Develop Vaccine against Giardia intestinalis

Vaccines, 2022
Giardia intestinalis (Giardia lambia, Giardia duodenalis) infections in humans may be asymptomatic or symptomatic and associated with diarrhea (without blood), abdominal cramps, bloating, flatulence, and weight loss.
Suthinee Sangkanu, Alok K. Paul, Julalak Chuprom, Watcharapong Mitsuwan, Rachasak Boonhok, Maria de Lourdes Pereira, Sonia Marlene Rodrigues Oliveira, Polrat Wilairatana, Mohammed Rahmatullah, Christophe Wiart, Muhammad Nawaz, Chea Sin, Sunil Kayesth, Veeranoot Nissapatorn   +13 more
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Parasite Carbohydrate Vaccines

Frontiers in Cellular and Infection Microbiology, 2017
Vaccination is an efficient means of combating infectious disease burden globally. However, routine vaccines for the world's major human parasitic diseases do not yet exist. Vaccines based on carbohydrate antigens are a viable option for parasite vaccine
Jonnel A. Jaurigue, Jonnel A. Jaurigue, Peter H. Seeberger, Peter H. Seeberger   +3 more
doaj   +1 more source