Wellcome Open Research, 2018 Antibodies against pathogens provide information on exposure to infectious agents and are meaningful measures of past and present infection. Antibodies were measured in the plasma of children that are the offspring in a population-based birth cohort, the
Ruth E. Mitchell +9 more
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VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases
Vaccines, 2021 Research on vaccines against trypanosomatids, a family of protozoa that cause neglected tropical diseases, such as Chagas disease, leishmaniasis, and sleeping sickness, is a current need.
Aline Maria Vasconcelos Queiroz +4 more
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The recombinant cysteine proteinase B (CPB) from Leishmania braziliensis and its domains: promising antigens for serodiagnosis of cutaneous and visceral leishmaniasis in dogs. [PDF]
, 2019 Leishmaniasis represents a group of parasitic diseases caused by a protozoan of the genus Leishmania and is widely distributed in tropical and subtropical regions.
Basombrío, Manuel Alberto +10 more
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Surface antigen cross-linking triggers forced exit of a protozoan parasite from its host. [PDF]
Proceedings of the National Academy of Sciences, 1996 We used the common fish pathogen Ichthyophthirius multifiliis as a model for studying interactions between parasitic ciliates and their vertebrate hosts. Although highly pathogenic, Ichthyophthirius can elicit a strong protective immune response in fish after exposure to controlled infections. To investigate the mechanisms underlying host resistance, a
T G, Clark, T L, Lin, H W, Dickerson
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Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle [PDF]
, 2017 Eimeria spp. are intracellular parasites that have a major impact on poultry. Effective live vaccines are available and the development of reverse genetic technologies has raised the prospect of using Eimeria spp.
Blake, D P +4 more
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Journal of Immunology Research, 2019 Malaria remains one the most infectious and destructive protozoan diseases worldwide. Plasmodium falciparum, a protozoan parasite with a complex life cycle and high genetic variability responsible for the difficulties in vaccine development, is ...
Agnieszka Szuster-Ciesielska +6 more
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Recombination-driven generation of the largest pathogen repository of antigen variants in the protozoan Trypanosoma cruzi [PDF]
BMC Genomics, 2016 The protozoan parasite Trypanosoma cruzi, causative agent of Chagas disease, depends upon a cell surface-expressed trans-sialidase (ts) to avoid activation of complement-mediated lysis and to enhance intracellular invasion. However these functions alone fail to account for the size of this gene family in T.
Weatherly, D. Brent +2 more
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Identification and Analysis of Immunodominant Antigens for ELISA-Based Detection of Theileria annulata. [PDF]
PLoS ONE, 2016 Tropical or Mediterranean theileriosis, caused by the protozoan parasite Theileria annulata, remains an economically important bovine disease in North Africa, Southern Europe, India, the Middle East and Asia.
Huseyin Bilgin Bilgic +7 more
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Surface antigenic change during differentiation of a parasitic protozoan, Leishmania mexicana: Identification by monoclonal antibodies. [PDF]
Proceedings of the National Academy of Sciences, 1982 The fusion of SP2/0 myeloma cells with spleen cells from mice immunized with Leishmania mexicana amazonensis promastigotes produced hybridoma clones. Indirect immunofluorescent antibody assay with live leishmanias showed that the monoclonal antibody 6H12 recognized only the antigens bound to the surface of L. mexicana amazonensis promastigotes. It also
Fong, D, Chang, K
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Dendritic cells in plasmodium infection [PDF]
, 2008 Infection with Plasmodium parasites (malaria) contributes greatly to morbidity and mortality in affected areas. Interaction of the protozoan with the immune system has a critical role in the pathogenesis of the disease, but may also hold a key to ...
Alonso +15 more
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