The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence [PDF]
, 2015 There are no commercially available vaccines against human protozoan parasitic diseases, despite the success of vaccination-induced long-term protection against infectious diseases.
Sonal Henson +29 more
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Stress-Dependent Expression of a Polymorphic, Charged Antigen in the Protozoan Parasite Entamoeba histolytica [PDF]
Infection and Immunity, 2003 ABSTRACT We have identified a novel stress inducible gene, Ehssp1 in Entamoeba histolytica , the causative agent of amebiasis. Ehssp1 belongs to a polymorphic, multigene family and is present on multiple chromosomes. No homologue of this gene was found in the NCBI database.
S, Satish +3 more
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Recombination-driven generation of the largest pathogen repository of antigen variants in the protozoan Trypanosoma cruzi [PDF]
BMC Genomics, 2016 The protozoan parasite Trypanosoma cruzi, causative agent of Chagas disease, depends upon a cell surface-expressed trans-sialidase (ts) to avoid activation of complement-mediated lysis and to enhance intracellular invasion. However these functions alone fail to account for the size of this gene family in T.
Weatherly, D. Brent +2 more
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Kinetoplastids: related protozoan pathogens, different diseases. [PDF]
, 2008 Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma and Leishmania, which are human pathogens with devastating health and economic effects. The sequencing of the genomes of some of these species has highlighted their
Gürtler, Ricardo E +17 more
core +1 more source
Wellcome Open Research, 2018 Antibodies against pathogens provide information on exposure to infectious agents and are meaningful measures of past and present infection. Antibodies were measured in the plasma of children that are the offspring in a population-based birth cohort, the
Ruth E. Mitchell +9 more
doaj +1 more source
VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases
Vaccines, 2021 Research on vaccines against trypanosomatids, a family of protozoa that cause neglected tropical diseases, such as Chagas disease, leishmaniasis, and sleeping sickness, is a current need.
Aline Maria Vasconcelos Queiroz +4 more
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Determinants of the relationship between cytokine production in pregnant women and their infants. [PDF]
, 2009 Exposure to environmental factors during fetal life and infancy is thought to play an important role in the early development of innate and adaptive immunity.
Supali, Taniawati +23 more
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High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing [PDF]
, 2012 BACKGROUND: Theileria parva is a tick-borne protozoan parasite, which causes East Coast Fever, a disease of cattle in sub-Saharan Africa. Like Plasmodium falciparum, the parasite undergoes a transient diploid life-cycle stage in the gut of the arthropod ...
Spooner Paul R +49 more
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Journal of Immunology Research, 2019 Malaria remains one the most infectious and destructive protozoan diseases worldwide. Plasmodium falciparum, a protozoan parasite with a complex life cycle and high genetic variability responsible for the difficulties in vaccine development, is ...
Agnieszka Szuster-Ciesielska +6 more
doaj +1 more source
Identification and Analysis of Immunodominant Antigens for ELISA-Based Detection of Theileria annulata. [PDF]
PLoS ONE, 2016 Tropical or Mediterranean theileriosis, caused by the protozoan parasite Theileria annulata, remains an economically important bovine disease in North Africa, Southern Europe, India, the Middle East and Asia.
Huseyin Bilgin Bilgic +7 more
doaj +1 more source