Results 11 to 20 of about 19,573 (217)

B-Cell Response during Protozoan Parasite Infections [PDF]

Journal of Parasitology Research, 2012
In this review, we discuss how protozoan parasites alter immature and mature B cell compartment. B1 and marginal zone (MZ) B cells, considered innate like B cells, are activated during protozoan parasite infections, and they generate short lived plasma ...
María C. Amezcua Vesely, Daniela A. Bermejo, Carolina L. Montes, Eva V. Acosta-Rodríguez, Adriana Gruppi   +4 more
doaj   +2 more sources

Characterization of the Fine Specificity of Bovine CD8 T-Cell Responses to Defined Antigens from the Protozoan ParasiteTheileria parva [PDF]

Infection and Immunity, 2008
ABSTRACTImmunity against the bovine intracellular protozoan parasiteTheileria parvahas been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells fromT. parva-immune cattle of different major histocompatibility complex (MHC) genotypes have been identified, raising the prospect of developing a subunit vaccine.
Graham, SP, Pellé, R, Yamage, M, Mwangi, DM, Honda, Y, Mwakubambanya, RS, de Villiers, EP, Abuya, E, Awino, E, Gachanja, J, Mbwika, F, Muthiani, AM, Muriuki, C, Nyanjui, JK, Onono, FO, Osaso, J, Riitho, V, Saya, RM, Ellis, SA, McKeever, DJ, MacHugh, ND, Gilbert, SC, Audonnet, JC, Morrison, WI, van der, Bruggen P, Taracha, EL   +25 more
openaire   +8 more sources

Diversity of Chagas disease diagnostic antigens: Successes and limitations. [PDF]

PLoS Neglected Tropical Diseases
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, remains a public health issue in endemic regions of the Americas, and is becoming globalised due to migration.
Tapan Bhattacharyya, Niamh Murphy, Michael A Miles   +2 more
doaj   +2 more sources

Far beyond Phagocytosis: Phagocyte-Derived Extracellular Traps Act Efficiently against Protozoan Parasites In Vitro and In Vivo

Mediators of Inflammation, 2016
Professional mononuclear phagocytes such as polymorphonuclear neutrophils (PMN), monocytes, and macrophages are considered as the first line of defence against invasive pathogens.
Liliana M. R. Silva, Tamara Muñoz-Caro, Rafael A. Burgos, Maria A. Hidalgo, Anja Taubert, Carlos Hermosilla   +5 more
doaj   +2 more sources

Host-specific targets of Histomonas meleagridis antigens revealed by immunoprecipitation

Scientific Reports
Histomonas meleagridis, a protozoan parasite responsible for histomonosis (syn. Blackhead disease, histomoniasis), presents an increasing challenge for poultry health, particularly with the ban of licensed prophylactic and treatment options.
Marcelo de Jesus Ramires, Karin Hummel, Tamas Hatfaludi, Michael Hess, Ivana Bilic   +4 more
doaj   +2 more sources

Immunoproteomics to identify species-specific antigens in Neospora caninum recognised by infected bovine sera

Parasite, 2022
Bovine neosporosis is a disease of concern due to its global distribution and significant economic impact through massive losses in the dairy and meat industries.
Udonsom Ruenruetai, Reamtong Onrapak, Adisakwattana Poom, Popruk Supaluk, Jirapattharasate Charoonluk, Nishikawa Yoshifumi, Inpankaew Tawin, Toompong Jitbanjong, Kotepui Manas, Mahittikorn Aongart   +9 more
doaj   +2 more sources

The immunogenic potential of an optimized mRNA lipid nanoparticle formulation carrying sequences from virus and protozoan antigens

Journal of Nanobiotechnology
Background Lipid nanoparticles (LNP) are a safe and effective messenger RNA (mRNA) delivery system for vaccine applications, as shown by the COVID-19 mRNA vaccines.
Renata S. Fernandes, Gabriela de Assis Burle-Caldas, Sarah Aparecida Rodrigues Sergio, Ana Flávia Bráz, Nathália Pereira da Silva Leite, Milton Pereira, Juliana de Oliveira Silva, Natália Satchiko Hojo-Souza, Bianca de Oliveira, Ana Paula S. Moura Fernandes, Flávio Guimarães da Fonseca, Ricardo Tostes Gazzinelli, Diego dos Santos Ferreira, Santuza M. Ribeiro Teixeira   +13 more
doaj   +3 more sources

Shared Mechanisms for Mutually Exclusive Expression and Antigenic Variation by Protozoan Parasites [PDF]

Frontiers in Cell and Developmental Biology, 2022
Cellular decision-making at the level of gene expression is a key process in the development and evolution of every organism. Variations in gene expression can lead to phenotypic diversity and the development of subpopulations with adaptive advantages.
Francesca Florini, Joseph E. Visone, Kirk W. Deitsch   +2 more
openaire   +3 more sources

Common strategies for antigenic variation by bacterial, fungal and protozoan pathogens [PDF]

Nature Reviews Microbiology, 2009
The complex relationships between infectious organisms and their hosts often reflect the continuing struggle of the pathogen to proliferate and spread to new hosts, and the need of the infected individual to control and potentially eradicate the infecting population.
Kirk W, Deitsch, Sheila A, Lukehart, James R, Stringer   +2 more
openaire   +2 more sources

Processing and presentation of antigens derived from intracellular protozoan parasites [PDF]

Current Opinion in Immunology, 2010
Control of parasitic protozoan infections requires the generation of efficient innate and adaptive immune responses, and in most cases both CD8 and CD4 T cells are necessary for host survival. Since intracellular protozoa remodel the vacuolar compartments in which they reside, it is not obvious how their antigens enter the MHC class I and class II ...
Romina S, Goldszmid, Alan, Sher
openaire   +2 more sources