Results 41 to 50 of about 19,573 (217)

Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species [PDF]

, 2012
Antigenic variation enables pathogens to avoid the host immune response by continual switching of surface proteins. The protozoan blood parasite Trypanosoma brucei causes human African trypanosomiasis ("sleeping sickness") across sub-Saharan Africa and ...
Browne, H., Jackson, Andrew P., Marcello, Lucio, Jackson, A.P., Jackson, A. P., Quail, M. A., Ginger, M. L., Marcello, L., Quail, M.A., Berriman, Matthew, Jackson, Andrew P, Berry, Andrew, Field, M. C., Aslett, Martin, Sanders, Mandy J., McQuillan, J., Barry, J. David, Field, Mark C., Allinson, Harriet C., Browne, Hilary, Hauser, H., Aslett, M., Barry, J.D., Burton, Peter, Allison, Harriet C., Ginger, Michael L., Gilderthorp, Ruth, Berry, A., van Tonder, Andries, Allison, H.C., McQuillan, Jacqueline, Burton, P., Ginger, M.L., Corton, Nicola, Gilderthorp, R., Hertz-Fowler, Christiane, Field, M.C., Field, MarkC., Corton, N., Quail, Michael A., Gamble, John, Brown, R., Otto, Thomas D., Otto, T. D., Barry, J. D., Gamble, J., Hauser, Heidi, Hertz-Fowler, C., Brown, Robert, van Tonder, A., Berriman, M., Ginger, Michael, Vavrova-Anderson, Jana, Vavrova-Anderson, J., Sanders, M.J., Allison, H. C., Hertz-Fowler, Christine, Otto, T.D., Sanders, M. J.   +58 more
core   +1 more source

Hiding inside the host: development and application of "Neospora caninum" bradyzoite in vitro culture [PDF]

, 2003
The bradyzoite stage of the apicomplexan parasite Neospora caninum represents a hypobiotic, slowly proliferating and tissue cyst forming stage, which can survive in the immunocompetent host for several years. Tissue cysts are orally infectious.
Vonlaufen, Nathalie
core   +1 more source

Rapid Diagnosis of Intestinal Parasitic Protozoa, with a Focus on Entamoeba histolytica

Interdisciplinary Perspectives on Infectious Diseases, 2009
Entamoeba histolytica is an invasive intestinal pathogenic parasitic protozoan that causes amebiasis. It must be distinguished from Entamoeba dispar and E.
Anjana Singh, Eric Houpt, William A. Petri   +2 more
doaj   +1 more source

Anticancer effects of parasite extracts of leishmaniasis and toxoplasma On resistant cell line (A2780-CP) and sensitive (A2780) to cisplatin [PDF]

زیست‌شناسی کاربردی, 2018
Cancer is one of the problems of human society that threatens human health. Since anti-cancer drugs have multiple side effects, identification of the biological processes and the protozoan antigens leads to the introduction of suitable candidates.
ameneh Elikaei, Hossein Vazini, Fatemeh Javani   +2 more
doaj   +1 more source

Fluorescence In Situ Hybridization (FISH) Tests for Identifying Protozoan and Bacterial Pathogens in Infectious Diseases

Diagnostics, 2022
Diagnosing and treating many infectious diseases depends on correctly identifying the causative pathogen. Characterization of pathogen-specific nucleic acid sequences by PCR is the most sensitive and specific method available for this purpose, although ...
Jyotsna S. Shah, Ranjan Ramasamy
doaj   +1 more source

CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen:Implications for parasite strain-specific immunity

, 2009
Although immunodominance of CD8(+) T-cell responses is a well-recognised feature of viral infections, its role in responses to more antigenically complex pathogens is less clear.
Connelley, T., Burrells, A, W. Ivan Morrison, Declan J. McKeever, Connelley, Timothy, Taracha, Evans L., Connelly, T, McKeever, DJ, Morrison, WI, Simon P. Graham, Burrells, A., MacHugh, ND, McKeever, D J, Taracha, E.L.N., Niall D. MacHugh, Roger Pelle, Ellis, SA, McKeever, Declan J., MacHugh, N D, Connelley, T, Evans L. Taracha, Ellis, S A, Graham, SP, Pelle, Roger, Ellis, Shirley A., MacHugh, Niall D., Formisano, Principia, Formisano, P, Principia Formisano, Taracha, EL, Ellis, S.A., Shirley A. Ellis, Taracha, E L, Alison Burrells, Pelle, R, IAH, Graham, Simon P., Graham, S P, Timothy Connelley, Formisano, P., Royal (Dick) School of Veterinary Studies, ILRI, Morrison, W. Ivan, Burrells, Alison, Graham, S.P.   +44 more
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Highly syntenic and yet divergent: a tale of two Theilerias [PDF]

, 2009
The published genomic sequences of the two major host-transforming Theileria species of cattle represent a rich resource of information that has allowed novel bioinformatic and experimental studies into these important apicomplexan parasites. Since their
Skilton, R., Villiers, Etienne P. de, Weir, W., de Villiers, E.P., Sunter, J., Bishop, Richard P., Bishop, R., Skilton, Robert A., Tait, A., Shiels, B., Langsley, G., Chaussepied, M.   +11 more
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A perspective on clonal phenotypic (antigenic) variation in protozoan parasites

Parasitology, 2002
Intra-clonal phenotypic (antigenic) variation is used by many pathogens to evade the consequences of immune-mediated killing by mammalian hosts. In this substantially theoretical article, I emphasise that antigenic variation (sensu stricto) involves no change in genotype; its importance as a mechanism for promoting pathogen transmission and its ...
openaire   +2 more sources

Surface antigenic change during differentiation of a parasitic protozoan, Leishmania mexicana: Identification by monoclonal antibodies. [PDF]

Proceedings of the National Academy of Sciences, 1982
The fusion of SP2/0 myeloma cells with spleen cells from mice immunized with Leishmania mexicana amazonensis promastigotes produced hybridoma clones. Indirect immunofluorescent antibody assay with live leishmanias showed that the monoclonal antibody 6H12 recognized only the antigens bound to the surface of L. mexicana amazonensis promastigotes. It also
Fong, D, Chang, K
openaire   +2 more sources

Surface antigen cross-linking triggers forced exit of a protozoan parasite from its host. [PDF]

Proceedings of the National Academy of Sciences, 1996
We used the common fish pathogen Ichthyophthirius multifiliis as a model for studying interactions between parasitic ciliates and their vertebrate hosts. Although highly pathogenic, Ichthyophthirius can elicit a strong protective immune response in fish after exposure to controlled infections. To investigate the mechanisms underlying host resistance, a
T G, Clark, T L, Lin, H W, Dickerson
openaire   +2 more sources