Results 191 to 200 of about 302,576 (367)

Trypanocidal Effects of Polyprenylated Benzophenone Enriched Brazilian Red Propolis Extract and Its Isolated Constituent

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
In vitro trypanocidal activity of a polyprenylated benzophenone‐enriched Brazilian red propolis extract (SEBz) and its major constituents, guttiferone E/xanthochymol (GUT/XAN) and oblongifolin B (OBL), exhibit in vitro trypanocidal activity against Trypanosoma cruzi, inducing ultrastructural damage with moderate cytotoxicity and no significant ...
Nicoli Dias Oliveira, Mariana Cintra Pagotti, Lucas Antonio de Lima Paula, Mariana Zaramello Paixão, Daiane Albino dos Santos, Renata Faleiros de Freitas, Sérgio Ricardo Ambrósio, Rodrigo Cassio Sola Veneziani, Jairo Kenupp Bastos, Lizandra Guidi Magalhães   +9 more
wiley   +1 more source

Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis

Science, 2018
Min Zhang, Chengqi Wang, T. Otto, J. Oberstaller, Xiangyu Liao, S. Adapa, Kenneth O. Udenze, I. Bronner, Debora Casandra, Matthew Mayho, Jacqueline Brown, Suzanne Li, J. Swanson, J. Rayner, R. Jiang, J. Adams   +15 more
semanticscholar   +1 more source

Two long non-coding RNAs generated from subtelomeric regions accumulate in a novel perinuclear compartment in Plasmodium falciparum

, 2012
Miguel Sierra-Miranda, Dulce Marı́a Delgadillo, Liliana Mâncio-Silva, Miguel Vargas, Nicolás Villegas‐Sepúlveda, Santiago Martı́nez-Calvillo, Artur Scherf, Rosaura Hernández‐Rivas   +7 more
openalex   +2 more sources

Unveiling the Leishmanicidal Mechanism of 4‐Nerolidylcatechol Isolated From Piper peltatum Against Leishmania infantum

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The present study assessed the leishmanicidal activity of 4‐nerolidylcatechol (4‐NC) (1) isolated from Piper peltatum leaves against promastigotes and amastigotes of Leishmania amazonensis, L. braziliensis, and L. infantum. The plant was fractionated, leading to the isolation and chemical identification of 4‐NC (1). Biochemical techniques were
Fabiana Brusco Lorenzetti, Rodolfo Bento Balbinot, Danielle Lazarin‐Bidóia, Viviane dos Santos Faiões, Eduardo Caio Torres‐Santos, Celso Vataru Nakamura, Tânia Ueda‐Nakamura, Diógenes Aparício Garcia Cortez, Benedito Prado Dias Filho   +8 more
wiley   +1 more source

Plasmodium Falciparum Malaria [PDF]

Journal of Clinical Investigation, 1982
John A. Schmidt, Iroka J. Udeinya, James H. Leech, Robert J. Hay, Masamichi Aikawa, John Barnwell, Ira Green, Louis H. Miller   +7 more
openaire   +1 more source

The global distribution of clinical episodes of Plasmodium falciparum malaria

Nature, 2005
R. Snow, C. Guerra, A. Noor, H. Myint, Simon Iain Hay   +4 more
semanticscholar   +1 more source

9‐Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys brasiliensis (Winteraceae).
Bruno Antonio Ferreira, Isabella Silva Cassimiro, Francyelle Borges Rosa de Moura, Tais de Campos Lima, Danielle Reis Napolitano, Eric Umehara, João Henrique Ghilardi Lago, Fernanda de Assis Araújo   +7 more
wiley   +1 more source

Prevalence of non-falciparum malaria infections among asymptomatic individuals in four regions of Mainland Tanzania

Parasites & Vectors
Background Recent studies point to the need to incorporate the detection of non-falciparum species into malaria surveillance activities in sub-Saharan Africa, where 95% of the world’s malaria cases occur.
Zachary R. Popkin-Hall, Misago D. Seth, Rashid A. Madebe, Rule Budodo, Catherine Bakari, Filbert Francis, Dativa Pereus, David J. Giesbrecht, Celine I. Mandara, Daniel Mbwambo, Sijenunu Aaron, Abdallah Lusasi, Samwel Lazaro, Jeffrey A. Bailey, Jonathan J. Juliano, Julie R. Gutman, Deus S. Ishengoma   +16 more
doaj   +1 more source

Exploration and Characterization of the Antimalarial Activity of Pyrimidine‐2,4‐Diamines for which Resistance is Mediated by the ABCI3 Transporter

ChemMedChem, Volume 21, Issue 1, January 2026.
Investigation of the structure‐activity relationship on W482 (1) with a pyrimidine‐2,4‐diamine scaffold culminated in analog 51 with enhanced anti‐plasmodial activity. Forward genetics and phenotypic examination revealed the ABCI3 transporter protein as a putative resistance mechanism.
Mahta Mansouri, Madeline G. Dans, Zijun Low, Katie Loi, Kate E. Jarman, Jocelyn S. Penington, Deyun Qiu, Adele M. Lehane, Benigno Crespo, Franciso‐Javier Gamo, Delphine Baud, Stephen Brand, Paul F. Jackson, Alan F. Cowman, Brad E. Sleebs   +14 more
wiley   +1 more source

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

Nature, 2013
F. Ariey, B. Witkowski, C. Amaratunga, J. Beghain, Anne-Claire Langlois, N. Khim, Saorin Kim, V. Duru, C. Bouchier, Laurence Ma, Pharath Lim, R. Leang, S. Duong, Sokunthea Sreng, Seila Suon, Char Meng Chuor, Denis Mey Bout, Sandie Ménard, W. Rogers, B. Genton, T. Fandeur, Olivo Miotto, P. Ringwald, J. Bras, A. Berry, J. Barale, R. Fairhurst, F. Benoit‐Vical, O. Mercereau‐Puijalon, D. Ménard   +29 more
semanticscholar   +1 more source