Results 281 to 290 of about 192,328 (309)
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Glycobiology of Plasmodium falciparum
Biochimie, 2001The human malaria parasite, Plasmodium falciparum, has as its only glycoconjugate GPI anchors. These structures, present in essentially all parasite surface proteins, are associated with disease pathology. In contrast, the parasite depends for essential recognition events on saccharides associated with host cell glycoproteins and proteoglycans.
D. Channe Gowda, Eugene A. Davidson
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Synchronization of Plasmodium falciparum erythrocytic stages in culture.
Journal of Parasitology, 1979Synchronous development of the erythrocytic stages of a human malaria parasite, Plasmodium falciparum, in culture was accomplished by suspending cultured parasites in 5% D-sorbitol and subsequent reintroduction into culture.
C. Lambros, J. Vanderberg
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Transfection of Plasmodium falciparum
2012Genetic manipulation of Plasmodium falciparum remains very challenging, mainly due to the parasite genome's high A/T-richness and low transfection efficiency. This chapter includes methods for generating transient and stable transfections by electroporation, allelic replacement with tagged genes, gene deletion, and the analysis of all the above.
Melanie Rug, Alexander G. Maier
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Curation of the Plasmodium falciparum genome
Trends in Parasitology, 2004The malaria genome has proved invaluable to researchers worldwide in the continuing fight against malaria by stimulating and underpinning molecular approaches in gene expression studies, vaccine and drug discovery research, and by providing data to facilitate hypothesis-driven research.
Berry, A.E. +4 more
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Plasmodium falciparum cytoadherence
Research in Immunology, 1991Sherman, I.W. (1979), Biochemistry of Plasmodium (malaria parasites). Microbiol. Rev., 43, 453-495. Strych, W., Miettinen-Baumann, A., Lottspeich, F. & Heidrich, H. (1987), Isolation and characterisation of the 80,000 dalton Plasmodium falciparum merozoite surface antigen. Parasit. Res., 73, 435441. Stryer, L.
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Plasmodium falciparum: Attenuation by irradiation
Experimental Parasitology, 1983The effect of irradiation on the in vitro growth of Plasmodium falciparum was investigated. The cultured malarial parasites at selected stages of development were exposed to gamma rays and the sensitivity of each stage was determined. The stages most sensitive to irradiation were the ring forms and the early trophozoites; late trophozoites were ...
Seiji Waki, Ichiro Yonome, Mamoru Suzuki
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Malabsorption in Plasmodium Falciparum Malaria
The American Journal of Tropical Medicine and Hygiene, 1972Abstract Impaired gastrointestinal function was detected during the acute phase of illness in patients with Plasmodium falciparum malaria. Nine of 11 (82%) had diminished D-xylose absorption, 6 of 10 (60%) had decreased absorption of vitamin B12, and 5 of 11 (45%) had low serum carotene levels.
Walter W. Karney, Myron J. Tong
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Mating Patterns of Plasmodium falciparum
Parasitology Today, 1998Recent empirical data have enabled a more informed debate over the extent of clonality in Plasmodium falciparum populations. Oocyst heterozygosity data reveal that the mating structure of malaria populations varies according to the transmission intensity.
R.E.L. Paul, Karen P. Day
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Adenine metabolism in Plasmodium falciparum
Experimental Parasitology, 2010Plasmodium falciparum lacks the de novo purine biosynthesis pathway and relies entirely on the salvage pathway to meet its purine nucleotide requirements. The entire flux for purine nucleotide biosynthesis in the parasite is believed to be through hypoxanthine guanine phosphoribosyltransferase (HGPRT), with the enzymes, adenosine kinase and adenine ...
Sonali Mehrotra +3 more
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Codon usage in Plasmodium falciparum
Molecular and Biochemical Parasitology, 1988The codon frequencies used in 7874 codons from 17 sequences of Plasmodium falciparum have been examined. The frequency distribution is markedly biased. A and C occur with similar frequency in all positions but G is predominantly in the first base and T is predominantly in the last position.
Allan Saul, Diana Battistutta
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