Results 21 to 30 of about 118,286 (167)

Healthy sweet inhibitor of Plasmodium falciparum aquaglyceroporin [PDF]

Biophysical Chemistry 198, 14-21 (2015), 2013
Plasmodium falciparum aquaglyceroporin (PfAQP) is a multifunctional channel protein in the plasma membrane of the malarial parasite that causes the most severe form of malaria infecting more than a million people a year. Finding a novel way to inhibit PfAQP, I conducted 3+ microseconds in silico experiments of an atomistic model of the PfAQP-membrane ...
arxiv   +1 more source

A Plasmodium falciparum host-targeting motif functions in export during blood stage infection of the rodent malarial parasite Plasmodium berghei. [PDF]

PLoS ONE, 2008
Plasmodium falciparum (P. falciparum) secretes hundreds of proteins--including major virulence proteins--into the host erythrocyte. In order to reach the host cytoplasm, most P. falciparum proteins contain an N terminal host-targeting (HT) motif composed
Julia J MacKenzie, Noé D Gómez, Souvik Bhattacharjee, Shaina Mann, Kasturi Haldar   +4 more
doaj   +1 more source

Analysis of slow (theta) oscillations as a potential temporal reference frame for information coding in sensory cortices [PDF]

, 2012
While sensory neurons carry behaviorally relevant information in responses that often extend over hundreds of milliseconds, the key units of neural information likely consist of much shorter and temporally precise spike patterns.
Christoph Kayser, Robin A. A. Ince, Stefano Panzeri, Tim Behrens   +3 more
core   +2 more sources

Molecular identification of Plasmodium species in symptomatic children of Democratic Republic of Congo

Malaria Journal, 2018
Background Worldwide, the highest malaria mortality is due to Plasmodium falciparum infection. However, other species of Plasmodium (Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and Plasmodium knowlesi) can also cause malaria.
Hugo Kavunga-Membo, Gillon Ilombe, Justin Masumu, Junior Matangila, Joël Imponge, Emile Manzambi, Francis Wastenga, Dieudonné Mumba Ngoyi, Jean-Pierre Van Geetruyden, Jean Jacques Muyembe   +9 more
doaj   +1 more source

Whole genome sequencing and microsatellite analysis of the Plasmodium falciparum E5 NF54 strain show that the var, rifin and stevor gene families follow Mendelian inheritance [PDF]

, 2018
Background: Plasmodium falciparum exhibits a high degree of inter-isolate genetic diversity in its variant surface antigen (VSA) families: P. falciparum erythrocyte membrane protein 1, repetitive interspersed family (RIFIN) and subtelomeric variable ...
Bruske, Ellen, Frank, Matthias, Otto, Thomas D.   +2 more
core   +5 more sources

Accuracy of malaria diagnosis by clinical laboratories in Belgium

Malaria Journal, 2019
Background The Belgian Reference Laboratory for Plasmodium offers a free-of-charge reference testing of malaria-positive or doubtful samples to clinical laboratories.
Laura Loomans, Anali Conesa Botella, Agnes D’hondt, Jacob Verschueren, Dorien Van den Bossche, Marjan Van Esbroeck, Jan Jacobs   +6 more
doaj   +1 more source

Simple Molecular Methods for Early Detection of Chloroquine Drug Resistance in Plasmodium vivax and Plasmodium falciparum [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Malaria is a human disease of which causes high morbidity and mortality. In Plasmodium falciparum malaria, the resistance to antimalarial drugs, especially chloroquine (CQ) is one of the paramount factors contributing to the global ...
Gurjeet Singh, Raksha Singh, Anant Dattatraya Urhehar   +2 more
doaj   +1 more source

PlasmoFAB: A Benchmark to Foster Machine Learning for Plasmodium falciparum Protein Antigen Candidate Prediction [PDF]

arXiv, 2023
Motivation: Machine learning methods can be used to support scientific discovery in healthcare-related research fields. However, these methods can only be reliably used if they can be trained on high-quality and curated datasets. Currently, no such dataset for the exploration of Plasmodium falciparum protein antigen candidates exists.
arxiv  

Plasmodium falciparum infection and the risk of anemia in school children [PDF]

Universa Medicina, 2013
Background According to the World Health Organization, malaria is the major cause of death from tropical infections in children and pregnant women. Severe anemia is a common complication of malaria, particularly malaria caused by Plasmodium falciparum ...
Suriyani Tan, Taniawati Supali, Heri Wibowo   +2 more
doaj  

Host reticulocytes provide metabolic reservoirs that can be exploited by malaria parasites [PDF]

, 2015
Human malaria parasites proliferate in different erythroid cell types during infection. Whilst Plasmodium vivax exhibits a strong preference for immature reticulocytes, the more pathogenic P. falciparum primarily infects mature erythrocytes.
Barrett, Michael P., Creek, Darren J., De Souza, David, Evans, Krystal J., McConville, Malcolm J., Muller, Sylke, Schofield, Louis, Srivastava, Anubhav, Waters, Andrew P.   +8 more
core   +1 more source