Results 21 to 30 of about 287,184 (330)
Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria.
Annual Review of Microbiology, 2020 Understanding and controlling the spread of antimalarial resistance, particularly to artemisinin and its partner drugs, is a top priority. Plasmodium falciparum parasites resistant to chloroquine, amodiaquine, or piperaquine harbor mutations in the P ...
Kathryn J. Wicht, Sachel Mok, D. Fidock
semanticscholar +1 more source
Malaria Journal, 2021 Background The entry of PCR-based techniques into malaria diagnostics has improved the sensitivity and specificity of the detection of Plasmodium infections.
Kim van Bergen +5 more
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Polymorphic antigens in Plasmodium falciparum [PDF]
Blood, 1989 5 years, a large number of these antigens have been cloned so that they may be investigated for their potential as components of a malaria vaccine. As a result of the sequencing studies on these cloned genes or gene fragments, a large amount of information has been obtained concerning the primary structural characteristics of Plasmodium fa/ciparum’ For
Jason Arthur Smythe, Robin F. Anders
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High prevalence of asymptomatic malaria infections in adults, Ashanti Region, Ghana, 2018
Malaria Journal, 2020 Background Ghana is among the high-burden countries for malaria infections and recently reported a notable increase in malaria cases. While asymptomatic parasitaemia is increasingly recognized as a hurdle for malaria elimination, studies on asymptomatic ...
Melina Heinemann +5 more
doaj +1 more source
Genomic epidemiology of artemisinin resistant malaria
eLife, 2016 The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent kelch13 mutations.
MalariaGEN Plasmodium falciparum Community Project
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An evolutionary perspective on the kinome of malaria parasites [PDF]
, 2012 Malaria parasites belong to an ancient lineage that diverged very early from the main branch of eukaryotes. The approximately 90-member plasmodial kinome includes a majority of eukaryotic protein kinases that clearly cluster within the AGC, CMGC, TKL ...
Andrew B. Tobin +6 more
core +1 more source
Parasites & Vectors, 2023 Background Malaria control efforts are highly skewed towards Plasmodium falciparum while overlooking other Plasmodium species such as P. malariae. A better understanding of the role of Plasmodium species other than P.
Daniel Nguiffo-Nguete +9 more
doaj +1 more source
Emerging Topics in Life Sciences, 2017 Plasmodium falciparum is a protozoan parasite that causes the most severe form of human malaria. Five other Plasmodium species can also infect humans — P. vivax, P. malariae, P. ovale curtisi, P. ovale wallikeri and P. knowlesi — but P. falciparum is the most prevalent Plasmodium species in the African region, where 90% of all malaria occurs, and it is
openaire +2 more sources
Characterization of Plasmodium falciparum glutamate dehydrogenase-soluble antigen
Brazilian Journal of Medical and Biological Research, 1998 The major aim of this study was to characterize a soluble Plasmodium falciparum antigen from the plasma of malaria-infected humans and Plasmodium falciparum culture supernatants, using immunoabsorbent techniques and Western blotting. An Mr 60-kDa protein
A. Rodríguez-Acosta +3 more
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The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015
Nature, 2015 Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital to inform future control planning.
S. Bhatt +31 more
semanticscholar +1 more source