Results 21 to 30 of about 301,675 (354)

Predicting gene expression in the human malaria parasite Plasmodium falciparum using histone modification, nucleosome positioning, and 3D localization features. [PDF]

, 2019
Empirical evidence suggests that the malaria parasite Plasmodium falciparum employs a broad range of mechanisms to regulate gene transcription throughout the organism's complex life cycle.
Cook, Kate, Le Roch, Karine G, Lu, Yang Y, Noble, William Stafford, Read, David F   +4 more
core   +2 more sources

Genetic Analysis and Species Specific Amplification of the Artemisinin Resistance-Associated Kelch Propeller Domain in P. falciparum and P. vivax. [PDF]

PLoS ONE, 2015
Plasmodium falciparum resistance to artemisinin has emerged in the Greater Mekong Subregion and now poses a threat to malaria control and prevention. Recent work has identified mutations in the kelch propeller domain of the P.
Eldin Talundzic, Stella M Chenet, Ira F Goldman, Dhruviben S Patel, Julia A Nelson, Mateusz M Plucinski, John W Barnwell, Venkatachalam Udhayakumar   +7 more
doaj   +1 more source

Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]

, 2017
Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani, Bunnik, Evelien M, Le Roch, Karine G, Lee, Michael, Lu, Xueqing Maggie, Prudhomme, Jacques   +5 more
core   +1 more source

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

Nature, 2015
Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital to inform future control planning.
S. Bhatt, D. Weiss, E. Cameron, D. Bisanzio, B. Mappin, U. Dalrymple, K. Battle, C. Moyes, Andrew J. Henry, P. Eckhoff, E. Wenger, O. Briët, O. Briët, M. Penny, M. Penny, T. Smith, T. Smith, A. Bennett, J. Yukich, T. Eisele, J. Griffin, C. Fergus, Michael Lynch, F. Lindgren, Justin M. Cohen, C. Murray, Dave L. Smith, Simon Iain Hay, Simon Iain Hay, Simon Iain Hay, R. Cibulskis, P. Gething   +31 more
semanticscholar   +1 more source

A microsporidian impairs Plasmodium falciparum transmission in Anopheles arabiensis mosquitoes

Nature Communications, 2020
A possible malaria control approach involves the dissemination in mosquitoes of inherited symbiotic microbes to block Plasmodium transmission. However, in the Anopheles gambiae complex, the primary African vectors of malaria, there are limited reports of
J. Herren, Lilian Mbaisi, Enock Mararo, E. E. Makhulu, V. Mobegi, Hellen Butungi, M. Mancini, J. Oundo, Evan Teal, Silvain Pinaud, M. Lawniczak, Jordan Jabara, G. Nattoh, S. Sinkins   +13 more
semanticscholar   +1 more source

Incidence of malarial infection and response to antimalarial drugs at Districts Lower Dir and Swat of Khyber Pakhtunkhwa, Pakistan

Dialogues in Health, 2022
Malaria is the leading cause of mortality and morbidity all over the world. Several antimalarial drugs are available for the treatment of malaria. The main objective of this study was to investigate the incidence of malarial infection and the use of ...
Nasib Zaman, Faiz Ul Haq, Zafran Khan, Wajahat Uallah, Daniya Ualiyeva, Yasir Waheed, Muhammad Rizwan, Raja Tahir Mahmood, Majid Mahmood   +8 more
doaj   +1 more source

Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space? [PDF]

, 2006
The organization and mining of malaria genomic and post-genomic data is highly motivated by the necessity to predict and characterize new biological targets and new drugs. Biological targets are sought in a biological space designed from the genomic data
Bastien, Olivier, Birkholtz, Lyn-Marie, Breton, Vincent, Grando, Delphine, Hofmann-Apitius, Martin, Jacq, Nicolas, Joubert, Fourie, Kasam, Vinod, Louw, Abraham I, Maréchal, Eric, Ortet, Philippe, Roy, Sylvaine, Saïdani, Nadia, Wells, Gordon, Zimmermann, Marc   +14 more
core   +4 more sources

Plasmodium falciparum infection and the risk of anemia in school children

Universa Medicina, 2015
BACKGROUND According to the World Health Organization, malaria is the major cause of death from tropical infections in children and pregnant women. Severe anemia is a common complication of malaria, particularly malaria caused by Plasmodium falciparum ...
Suriyani Tan, Taniawati Supali, Heri Wibowo   +2 more
doaj   +1 more source

Analysis of nucleosome positioning landscapes enables gene discovery in the human malaria parasite Plasmodium falciparum. [PDF]

, 2015
BackgroundPlasmodium falciparum, the deadliest malaria-causing parasite, has an extremely AT-rich (80.7 %) genome. Because of high AT-content, sequence-based annotation of genes and functional elements remains challenging.
Bunnik, Evelien M, Le Roch, Karine G, Lonardi, Stefano, Lu, Xueqing Maggie, Nasseri, Sara, Pokhriyal, Neeti   +5 more
core   +2 more sources

Klasifikasi Citra Plasmodium Penyebab Penyakit Malaria dalam Sel Darah Merah Manusia dengan Menggunakan Metode Multi Class Support Vector Machine (SVM)

Ilkom Jurnal Ilmiah, 2016
Malaria adalah penyakit kronis dan akut yang disebabkan oleh protozoa dari jenis Plasmodium. Ada 4 spesies yang utama dari jenis plasmodium yang menyebabkan penyakit malaria pada manusia, yaitu: Plasmodium falciparum, Plasmodium vivax, Plasmodium ...
Nur Ain Banyal, Surianti Surianti, Abdul Rachman Dayat   +2 more
doaj   +1 more source