Results 291 to 300 of about 192,328 (309)
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Pigment biocrystallization in Plasmodium falciparum
Trends in Parasitology, 2002Malaria parasites catabolize hemoglobin as an important source of amino acids. One consequence of this dependence on hemoglobin degradation is the need for an effective detoxification mechanism for hematin (Fig. 1Fig. 1a,b). To date, the only definitively characterized product of hematin in the parasite is the malaria pigment hemozoin.
Ernst Hempelmann, Timothy J. Egan
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Intraspecific Variation in Plasmodium Falciparum
The American Journal of Tropical Medicine and Hygiene, 1974Abstract Significant structural differences are observed between the chloroquine-resistant Vietnam (Smith) strain and the chloroquine-sensitive Malaya (Camp-Sadun) strain of Plasmodium falciparum. The Vietnam strain shows subpellicular microtubules in the gametocyte, granular aggregates of the nucleus and enlargement of food vacuoles in the gametocyte ...
Ronald A. Ward, Masamichi Aikawa
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Sequencing the genome of Plasmodium falciparum
Current Opinion in Infectious Diseases, 1998Advances in microbial genomic sequencing have the potential to revolutionize the control of infectious diseases. Recently, a consortium of researchers and funding agencies from the United States and Great Britain have embarked on a project to sequence the genome from Plasmodium falciparum, the most important cause of human malaria.
Leda M. Cummings +7 more
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Chloroquine Resistance in Plasmodium Falciparum
The American Journal of Tropical Medicine and Hygiene, 1961Summary The response to chloroquine of a strain of Plasmodium falciparum malaria from Colombia, South America, has been studied in seven patients. Six of these infections responded poorly to normal (0.6 gram, 1.5 grams) and above normal (2.1 grams) doses of the drug. The parasites were either not cleared from the blood stream or were eliminated slowly,
Martin D. Young, Donald V. Moore
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Antibodies and Plasmodium falciparum merozoites
Trends in Parasitology, 2001There is considerable interest in using merozoite proteins in a vaccine against falciparum malaria. Observations that antibodies to merozoite surface proteins block invasion are a basis for optimism. This article draws attention to important and varied aspects of how antibodies to Plasmodium falciparum merozoites affect red blood cell invasion.
Ranjan Ramasamy +2 more
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Genetic Diversity in Plasmodium falciparum
1990Publisher Summary This chapter focuses on those forms of genetic diversity that are clearly understood at the deoxyribonucleic acid (DNA) level. The application of recombinant DNA technology to the study of Plasmodium falciparum and other species of Plasmodium has resulted in rapid advances in the understanding of genetic diversity in malaria ...
David Walliker +2 more
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The Plasmodium falciparum Genome Project
Parasitology Today, 1998National Center for Biotechnology Information (NCBI) BLAST searches on Apicomplexan sequence data◦http://www.ncbi.nlm.nih.gov/Malaria/Malaria Genetics Section; NIAID/NIH◦www.ncbi.nlm.nih.gov/malaria/NIAID malaria research and reference reagent repository◦http://www.niaid.nih.gov/reposit/malrep.htmMalaria Genome Mapping Data; WEHI/Monash University◦http:
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Mefloquine resistance in Plasmodium falciparum
Parasitology Today, 1995Mefloquine resistance in Plasmodium falciparum, the most dangerous of the four pathogenic malaria parasites of humans, is established in several endemic regions of the world. After a promising start, resistance has developed to disturbing extents in some areas, whereas in many regions it remains an effective drug.
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Selection and Synergy in Plasmodium falciparum
Parasitology Today, 1999Sims, P., Wang, P., Hyde, J. E.
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Antibodies against Plasmodium falciparum malaria at the molecular level
Nature reviews. Immunology, 2019J. Julien, H. Wardemann
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