Results 181 to 190 of about 67,974 (216)
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Protein kinase 9 is not required for completion of the Plasmodium berghei life cycle
Microbiological Research, 2022Protein kinases uniquely expressed in Plasmodium represent attractive drug targets. Previous studies have reported that Plasmodium falciparum Protein kinase 9 (Pk9) phosphorylates regulatory serine 106 of the ubiquitin-conjugating enzyme (Ubc13) thereby negatively regulating its activity.
Sunil Kumar, Narwal +3 more
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Plasmodium Egress Across the Parasite Life Cycle
Annual Review of Microbiology, 2022Human malaria, caused by infection with Plasmodium parasites, remains one of the most important global public health problems, with the World Health Organization reporting more than 240 million cases and 600,000 deaths annually as of 2020 ( World malaria report 2021).
Jeffrey D, Dvorin, Daniel E, Goldberg
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Single-cell views of the Plasmodium life cycle
Trends in Parasitology, 2022Malaria-causing Plasmodium parasites undergo multiple phenotypic transitions as they cycle between diverse niches in the mammalian and mosquito hosts. Recent applications of single-cell technologies to Plasmodium have enabled the systematic investigation of the distinct stages across the life cycle.
Real, Eliana, Mancio-Silva, Liliana
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Melatonin Effects on Plasmodium Life Cycle: New Avenues for Therapeutic Approach
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery, 2012Malaria remains a global health problem affecting more than 515 million people all over the world including Malaysia. It is on the rise, even within unknown regions that previous to this were free of malaria. Although malaria eradication programs carried out by vector control programs are still effective, anti-malarial drugs are also used extensively ...
Venkataramanujam, Srinivasan +3 more
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Life-Cycle of Plasmodium Relictum Var. Matutinum
The American Journal of Tropical Medicine and Hygiene, 1940Summary and Conclusions 1. Exoerythrocytic schizogony has been looked for in 18 cases of infection with Plasmodium relictum var. matutinum, and demonstrated in 9. It has been found both in blood-induced infections and those resulting from the bites of infected mosquitoes. 2.
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Crossreactive antigens between life cycle stages ofplasmodium faiciparum
Parasitology Today, 1992The high mortality and morbidity induced by falciparum malaria has motivated research to find an efficient antimalarial vaccine. The parasite has a complex life cycle, both in the mosquito and human hosts, and presents a number of potential targets for vaccine-induced immune attack.
I I, Moelans, J G, Schoenmakers
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1990
Recent evidence has suggested that extensive changes in the phosphorylation profile of red cell membrane proteins are associated with the invasion and development of the malarial parasite. In order to further define the role of parasite protein phosphorylation in these events we have looked at this phosphorylation using: (1) continuous metabolic ...
G L, Jones, H M, Edmundson
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Recent evidence has suggested that extensive changes in the phosphorylation profile of red cell membrane proteins are associated with the invasion and development of the malarial parasite. In order to further define the role of parasite protein phosphorylation in these events we have looked at this phosphorylation using: (1) continuous metabolic ...
G L, Jones, H M, Edmundson
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[Morphology, biology and life-cycle of Plasmodium parasites].
Bulletin de l'Academie nationale de medecine, 2008Laveran first discovered that an infectious agent was responsible for malaria by using a simple microscope, without the assistance of specific stains. Our knowledge of the Plasmodium life cycle and cellular biology has progressed with each technological advance, from Romanovsky staining and histology to electron microscopy, immunocytochemistry ...
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Plasmodium vivax: modern strategies to study a persistent parasite's life cycle.
Advances in parasitology, 2013Plasmodium vivax has unique attributes to support its survival in varying ecologies and climates. These include hypnozoite forms in the liver, an invasion preference for reticulocytes, caveola-vesicle complex structures in the infected erythrocyte membrane and rapidly forming and circulating gametocytes.
Mary R, Galinski +2 more
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An ApiAp2 Transcription Factor with a Dispensable Role in Plasmodium berghei Life Cycle
ACS Infectious DiseasesMalaria parasites have a complex life cycle and undergo replication and population expansion within vertebrate hosts and mosquito vectors. These developmental transitions rely on changes in gene expression and chromatin reorganization that result in the activation and silencing of stage-specific genes. The ApiAp2 family of DNA-binding proteins plays an
null Nirdosh +2 more
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