Results 41 to 50 of about 8,376 (128)

Species and genotype diversity of Plasmodium in malaria patients from Gabon analysed by next generation sequencing

Malaria Journal, 2017
Background Six Plasmodium species are known to naturally infect humans. Mixed species infections occur regularly but morphological discrimination by microscopy is difficult and multiplicity of infection (MOI) can only be evaluated by molecular methods ...
Albert Lalremruata, Sankarganesh Jeyaraj, Thomas Engleitner, Fanny Joanny, Annika Lang, Sabine Bélard, Ghyslain Mombo-Ngoma, Michael Ramharter, Peter G. Kremsner, Benjamin Mordmüller, Jana Held   +10 more
doaj   +1 more source

Global prevalence and mortality of severe Plasmodium malariae infection: a systematic review and meta-analysis

Malaria Journal, 2020
Background Severe complications among patients with Plasmodium malariae infection are rare. This is the first systematic review and meta-analysis demonstrating the global prevalence and mortality of severe P. malariae infection in humans.
Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni D. Milanez, Frederick R. Masangkay   +3 more
doaj   +1 more source

Plasmodium Parasitemia and Its Relationship With Hematological, Liver, and Kidney Function of Patients With Falciparum Malaria in the Eastern Region, Ghana

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Malaria remains a significant public health challenge in Sub‐Saharan Africa, including Ghana. Children and adults present with varying clinical and biochemical pictures in response to Plasmodium infection. Thus, the study aimed to explore the relationship between Plasmodium parasitemia and hematological, liver, and kidney function ...
Augustine Badu, Isaac Darban, Kofi Mensah, Maxwell Hubert Antwi, Mark Appeaning, Aaron Siaw Kwakye, Tonnies Abeku Buckman, Vidic Kwarteng Owusu, Daniel Takyi Mintah, Raymond Ansah Agyei, Comfort Yeboah, Daniel Acorlor   +11 more
wiley   +1 more source

Molecular Detection of Plasmodium malariae/Plasmodium brasilianum in Non-Human Primates in Captivity in Costa Rica.

PLoS ONE, 2017
One hundred and fifty-two blood samples of non-human primates of thirteen rescue centers in Costa Rica were analyzed to determine the presence of species of Plasmodium using thick blood smears, semi-nested multiplex polymerase chain reaction (SnM-PCR ...
Alicia Fuentes-Ramírez, Mauricio Jiménez-Soto, Ruth Castro, Juan José Romero-Zuñiga, Gaby Dolz   +4 more
doaj   +1 more source

Genomic Insights Into Host Shifts Between Plasmodium vivax and Plasmodium simium in Latin America

Evolutionary Applications, Volume 19, Issue 3, March 2026.
ABSTRACT Malaria in Latin America is largely caused by Plasmodium vivax, but the closely related monkey parasite Plasmodium simium has recently been observed in humans, thus raising new public health concerns. By screening 719 monkey samples from five Latin America countries, we identified 23 Plasmodium‐positives.
Margaux J. M. Lefebvre, Fanny Degrugillier, Céline Arnathau, Camila González, Silvia Rondón, Andrés Link, Andrea Chaves, Julio A. Benavides, Aline Alves Scarpellini Campos, Edmilson dos Santos, Rosana Huff, Cláudia Maria Dornelles da Silva, Ezequiel Vanderhoeven, Benoit De Thoisy, Michael C. Fontaine, Franck Prugnolle, Virginie Rougeron   +16 more
wiley   +1 more source

Small Molecule Kinase Inhibitors with In Vitro β‐Hematin Formation and Plasmodium falciparum Protein Kinase G Inhibitory Activity Identified Using Machine Learning

ChemMedChem, Volume 21, Issue 3, 12 February 2026.
A random forest machine learning model was used in combination with molecular docking to predict activity of small molecule kinase inhibitors against two crucial antimalarial targets, namely hemozoin crystallization and Plasmodium falciparum protein kinase G. Derazantinib shows most promise as a dual inhibitor.
Jessica L. Thibaud, Nicolaas Salomane, Sarah Harries, Kathryn J. Wicht, Lauren B. Coulson, David Kuter, Kelly Chibale, Katherine A. de Villiers   +7 more
wiley   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, Volume 301, Issue 2, Page 280-329, February 2026.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

Evaluation of the Clearview^® malaria pLDH malaria rapid diagnostic test in a non-endemic setting

Malaria Journal, 2011
Background Malaria Rapid Diagnostic Tests (RDTs) are widely used to diagnose malaria. The present study evaluated a new RDT, the Clearview® Malaria pLDH test targeting the pan-Plasmodium antigen lactate dehydrogenase (pLDH).
Rivetz Baruch, Cohen Dorit, Hubert Véronique, Houzé Sandrine, Le Bras Jacques   +4 more
doaj   +1 more source

Immune Modulation by Plasmodium yoelii: Insights From Lethal and Non‐Lethal Strains

Parasite Immunology, Volume 48, Issue 1, January 2026.
ABSTRACT Malaria pathogenesis is driven by intricate host–parasite interactions that determine immune balance and clinical outcome. The Plasmodium yoelii model, particularly its lethal (17XL) and non‐lethal (17XNL) strains, provides a robust framework to investigate these dynamics.
Sharoen Yu Ming Lim
wiley   +1 more source