Results 91 to 100 of about 150,966 (275)

Designing and Cloning of the Gene Vaccine Carrying the Viral Haemorrhagic Septicaemia Multi‐Epitope Gene in the pNZ8121 Secretion Vector

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
Viral haemorrhagic septicaemia virus (VHSV) immunogenic epitopes were used to design a multi‐epitope vaccine with adjuvant. The vaccine's properties, structure and TLR‐4 interaction were analysed via computational methods. Optimized nucleotide sequences were created for Lactococcus lactis expression.
Ramin Shukripour, Abbas Doosti, Mohsen Forouzanfar, Mojtaba Jafarinia   +3 more
wiley   +1 more source

Resolving the cause of recurrent Plasmodium vivax malaria probabilistically

Nature Communications, 2019
Relapses arising from dormant liver-stage Plasmodium vivax parasites (hypnozoites) are a major cause of vivax malaria. However, in endemic areas, a recurrent blood-stage infection following treatment can be hypnozoite-derived (relapse), a blood-stage ...
A. Taylor, J. Watson, C. Chu, Kanokpich Puaprasert, Jureeporn Duanguppama, N. Day, F. Nosten, D. Neafsey, C. Buckee, M. Imwong, N. White   +10 more
semanticscholar   +1 more source

Comparative Evaluation of Available Immune-Chromatographic Tests Used for Detection of Plasmodium Species, A Tertiary Care Hospital Experience

Pakistan Armed Forces Medical Journal
Objective: To test the sensitivity of locally available strips for the detection of Plasmodium Vivax and Plasmodium Falciparum species at a tertiary care hospital. Study Design: Cross-sectional study.
Nabila Rafique, Mohammad Abdul Naeem, Maria Khan, Muhammad Bilal Asghar, Zohra Farooq, Sobia Umar   +5 more
doaj   +1 more source

Programmable reconfiguration of Physarum machines [PDF]

Natural Computing Volume 9, 2009, Number 1, 219-23, 2009
Plasmodium of Physarum polycephalum is a large cell capable of solving graph-theoretic, optimization and computational geometry problems due to its unique foraging behavior. Also the plasmodium is unique biological substrate that mimics universal storage modification machines, namely the Kolmogorov-Uspensky machine.
arxiv   +1 more source

Tackling resistance: Emerging antimalarials and new parasite targets in the era of elimination [version 1; referees: 2 approved] [PDF]

, 2018
Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for infection with Plasmodium spp. parasites.
Matthews, Emily S, Odom John, Audrey R
core   +2 more sources

A Brief Molecular History of Vγ9Vδ2 TCR‐Mediated Phosphoantigen Sensing

Immunological Reviews, Volume 331, Issue 1, May 2025.
ABSTRACT Vγ9Vδ2 T‐cells are universally present in humans and represent one of the most prevalent TCR reactivities, evolutionarily conserved across diverse mammalian species. They are an innate‐like subset featuring a semi‐invariant TCR repertoire that drives their well‐recognized reactivity to small, non‐peptidic phosphoantigens (pAg). Crucially, they
Fiyaz Mohammed, Carrie R. Willcox, Benjamin E. Willcox   +2 more
wiley   +1 more source

An ultrasensitive reverse transcription polymerase chain reaction assay to detect asymptomatic low-density Plasmodium falciparum and Plasmodium vivax infections in small volume blood samples. [PDF]

, 2015
BackgroundHighly sensitive, scalable diagnostic methods are needed to guide malaria elimination interventions. While traditional microscopy and rapid diagnostic tests (RDTs) are suitable for the diagnosis of symptomatic malaria infection, more sensitive ...
Adams, Matthew, Han, Kay Thwe, Han, Zay Yar, Hlaing, Tin Maung, Huang, Fang, Johnson, Nicole Eddington, Joshi, Sudhaunshu N, Mbambo, Gillian, Mu, Amy Z, Nyunt, Myaing M, Oo, Khine Zaw, Plowe, Christopher V, Richards, Adam K, Roemmich, Shay M, Shrestha, Biraj, Strauss, Kathy A, Thura, Si   +16 more
core   +2 more sources

Improved genetic screening with zygosity detection through multiplex high‐resolution melting curve analysis and biochemical characterisation for G6PD deficiency

Tropical Medicine &International Health, Volume 30, Issue 5, Page 437-457, May 2025.
Abstract Accurate diagnosis of glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is crucial for relapse malaria treatment using 8‐aminoquinolines (primaquine and tafenoquine), which can trigger haemolytic anaemia in G6PD‐deficient individuals. This is particularly important in regions where the prevalence of G6PD deficiency exceeds 3%–5%, including ...
Usa Boonyuen, Beatriz Aira C. Jacob, Kamonwan Chamchoy, Natnicha Pengsuk, Sirinyatorn Talukam, Chanya Petcharat, Emily R. Adams, Thomas Edwards, Kobporn Boonnak, Syazwani Itri Amran, Nurriza Ab Latif, Naveen Eugene Louis   +11 more
wiley   +1 more source

Measuring ex vivo drug susceptibility in Plasmodium vivax isolates from Cambodia

Malaria Journal, 2017
Background While intensive Plasmodium falciparum multidrug resistance surveillance continues in Cambodia, relatively little is known about Plasmodium vivax drug resistance in Cambodia or elsewhere. To investigate P.
Suwanna Chaorattanakawee, Chanthap Lon, Soklyda Chann, Kheang Heng Thay, Nareth Kong, Yom You, Siratchana Sundrakes, Chatchadaporn Thamnurak, Sorayut Chattrakarn, Chantida Praditpol, Kritsanai Yingyuen, Mariusz Wojnarski, Rekol Huy, Michele D. Spring, Douglas S. Walsh, Jaymin C. Patel, Jessica Lin, Jonathan J. Juliano, Charlotte A. Lanteri, David L. Saunders   +19 more
doaj   +1 more source

Escherichia coli in the production of biopharmaceuticals

Biotechnology and Applied Biochemistry, Volume 72, Issue 2, Page 528-541, April 2025.
Abstract Escherichia coli has shouldered a massive workload with the discovery of recombinant DNA technology. A new era began in the biopharmaceutical industry with the production of insulin, the first recombinant protein, in E. coli and its use in treating diabetes. After insulin, many biopharmaceuticals produced from E. coli have been approved by the
İbrahim İncir, Özlem Kaplan
wiley   +1 more source