Results 31 to 40 of about 32,997 (179)
Erythrocyte membrane protein 3 (EMAP3) is a novel Plasmodium berghei protein that is trafficked to the outer membrane surface of the infected red blood cell (iRBC). EMAP3 is not critical for parasite growth or sequestration but offers a new scaffold for displaying Plasmodium falciparum proteins on iRBCs.
Sophia Raine C. Hernandez +13 more
wiley +1 more source
Malaria polymerase chain reaction (PCR) testing is more sensitive than conventional diagnostics. Routine PCR screening of at‐risk asymptomatic hematopoietic cell donors and transplant candidates may prevent unnecessary deferrals or treatment. In our experience, PCR negativity during screening or after treatment supports donor/candidate eligibility ...
Mary M. Czech +5 more
wiley +1 more source
Malaria cerebral con pancitopenia por Plasmodium vivax en la Amazonía peruana: reporte de caso
Plasmodium vivax es la especie más común en la Amazonía peruana y ocasiona el 81% del total de casos de malaria. Presentamos el caso de un paciente adulto varón con malaria cerebral por Plasmodium vivax, que inicia con malestar general y fiebre, luego ...
Marco Paredes-Obando +9 more
doaj +1 more source
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha +5 more
wiley +1 more source
Ecologies of Risk: Malaria and Settler Landscape Transformation in 19th‐Century Ontario
ABSTRACT Objectives This study examines how settler‐driven environmental change shaped malaria transmission and mortality in 19th‐century southern Ontario. It aimed to understand the biosocial and ecological conditions that sustained endemic malaria in a temperate, colonial context.
Amanda Cooke, Megan B. Brickley
wiley +1 more source
Objective: To test the sensitivity of locally available strips for the detection of Plasmodium Vivax and Plasmodium Falciparum species at a tertiary care hospital. Study Design: Cross-sectional study.
Nabila Rafique +5 more
doaj +1 more source
Pharmacogenomics in clinical practice: Biomarker information in Brazilian drug labels
This review examines the PGx annotations in package inserts (bulas in Brazilian Portuguese) approved by ANVISA, the Brazilian Health Regulatory Agency, for 19 gene–drug pairs with strong or moderate recommendations for initial dosing alteration in the CPIC (Clinical Pharmacogenetic Implementation Consortion) guidelines and PGx testing required or ...
Guilherme Suarez‐Kurtz
wiley +1 more source
Measuring ex vivo drug susceptibility in Plasmodium vivax isolates from Cambodia
Background While intensive Plasmodium falciparum multidrug resistance surveillance continues in Cambodia, relatively little is known about Plasmodium vivax drug resistance in Cambodia or elsewhere. To investigate P.
Suwanna Chaorattanakawee +19 more
doaj +1 more source
Host–parasite oxidative arms race: who will win?
Avian haemosporidian parasites are globally widespread with a broad repertoire of hosts. When infected, the host can either reduce (resistance) and/or limit the severity of parasitaemia (tolerance). Oxidative stress plays a pivotal role in the host's resistance and tolerance, as well as its detrimental endpoints.
Caroline Isaksson +3 more
wiley +1 more source
A Machine Learning‐Based Dynamic SST Index for Long‐Lead Malaria Prediction in the Peruvian Amazon
Abstract Malaria imposes a major health burden in the Peruvian Amazon, and its early warning is essential for effective disease prevention. The tropical sea surface temperature (SST) variability, fundamentally shaping the global weather patterns, may also alter malaria transmission and potentially improve its long‐lead predictability. In this study, we
Mengxin Pan +7 more
wiley +1 more source

