Results 101 to 110 of about 50,182 (219)

Rapid Diagnostic Testing for Plasmodium vivax and Nonfalciparum Malaria in Endemic Areas [PDF]

, 2015
Clinical Question How sensitive and specific are rapid diagnostic tests (RDTs) for diagnosing Plasmodium vivax and nonfalciparum malaria in endemic areas?
Abba, Katharine, Garner, Paul, Takwoingi, Yemesi   +2 more
core   +3 more sources

Genomic Insights Into Host Shifts Between Plasmodium vivax and Plasmodium simium in Latin America

Evolutionary Applications, Volume 19, Issue 3, March 2026.
ABSTRACT Malaria in Latin America is largely caused by Plasmodium vivax, but the closely related monkey parasite Plasmodium simium has recently been observed in humans, thus raising new public health concerns. By screening 719 monkey samples from five Latin America countries, we identified 23 Plasmodium‐positives.
Margaux J. M. Lefebvre, Fanny Degrugillier, Céline Arnathau, Camila González, Silvia Rondón, Andrés Link, Andrea Chaves, Julio A. Benavides, Aline Alves Scarpellini Campos, Edmilson dos Santos, Rosana Huff, Cláudia Maria Dornelles da Silva, Ezequiel Vanderhoeven, Benoit De Thoisy, Michael C. Fontaine, Franck Prugnolle, Virginie Rougeron   +16 more
wiley   +1 more source

Detecting signatures of balancing selection to identify targets of anti-parasite immunity.

, 2010
Parasite antigen genes might evolve under frequency-dependent immune selection. The distinctive patterns of polymorphism that result can be detected using population genetic methods that test for signatures of balancing selection, allowing genes encoding
Conway, David J, Weedall, Gareth D
core   +1 more source

Erythrocyte Membrane Protein 3 (EMAP3) Is Exposed on the Surface of the Plasmodium berghei Infected Red Blood Cell

Molecular Microbiology, Volume 125, Issue 3, Page 233-249, March 2026.
Erythrocyte membrane protein 3 (EMAP3) is a novel Plasmodium berghei protein that is trafficked to the outer membrane surface of the infected red blood cell (iRBC). EMAP3 is not critical for parasite growth or sequestration but offers a new scaffold for displaying Plasmodium falciparum proteins on iRBCs.
Sophia Raine C. Hernandez, Ravish Rashpa, Thorey K. Jonsdottir, Martina S. Paoletta, Josy ter Beek, María Rayón Díaz, Jelte M. M. Krol, Severine Chevalley‐Maurel, Takahiro Ishizaki, Ronnie P.‐A. Berntsson, Chris J. Janse, Blandine Franke‐Fayard, Mathieu Brochet, Ellen S. C. Bushell   +13 more
wiley   +1 more source

Artemisinin‐Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control

Tropical Medicine &International Health, Volume 31, Issue 3, Page 254-273, March 2026.
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha, Addisu Afrassa Tegegne, Tapfumanei Mashe, Million Girma, Gemmechu Hasen, Sileshi Belew   +5 more
wiley   +1 more source

Plasmodium vivax malaria presenting with severe thrombocytopenia

Brazilian Journal of Infectious Diseases, 2002
Plasmodium falciparum and Plasmodium vivax malaria are endemic infections in India and are commonly associated with mild hematological abnormalities. Severe thrombocytopenia is common in isolated falciparum and mixed falciparum/vivax malaria, but is very
Makkar Ravinder Pal Singh, Monga Surabhi Mukhopadhyay Amitabh, Gupta Ajay Kr.   +2 more
doaj  

Small Molecule Kinase Inhibitors with In Vitro β‐Hematin Formation and Plasmodium falciparum Protein Kinase G Inhibitory Activity Identified Using Machine Learning

ChemMedChem, Volume 21, Issue 3, 12 February 2026.
A random forest machine learning model was used in combination with molecular docking to predict activity of small molecule kinase inhibitors against two crucial antimalarial targets, namely hemozoin crystallization and Plasmodium falciparum protein kinase G. Derazantinib shows most promise as a dual inhibitor.
Jessica L. Thibaud, Nicolaas Salomane, Sarah Harries, Kathryn J. Wicht, Lauren B. Coulson, David Kuter, Kelly Chibale, Katherine A. de Villiers   +7 more
wiley   +1 more source

Evaluation of Three Rapid Tests for Diagnosis of P. Falciparum and P. Vivax Malaria in Colombia. [PDF]

, 2006
The diagnostic capacity of three malaria rapid diagnostic tests (RDTs), NOW-Malaria-ICT, OptiMAL-IT, and Paracheck-Pf, was evaluated against expert microscopy in Colombia. We tested 896 patients, of whom microscopy confirmed 139 P.
Angarita, B, Counihan, H, Gordillo, F, Guthmann, J P, Hamade, P, Hill, O, van den Broek, I   +6 more
core   +1 more source

Characterizing Antibody Responses to Plasmodium vivax and Plasmodium falciparum Antigens in India Using Genome-Scale Protein Microarrays.

PLoS Neglected Tropical Diseases, 2017
Understanding naturally acquired immune responses to Plasmodium in India is key to improving malaria surveillance and diagnostic tools. Here we describe serological profiling of immune responses at three sites in India by probing protein microarrays ...
Swapna Uplekar, Pavitra Nagesh Rao, Lalitha Ramanathapuram, Vikky Awasthi, Kalpana Verma, Patrick Sutton, Syed Zeeshan Ali, Ankita Patel, Sri Lakshmi Priya G, Sangamithra Ravishankaran, Nisha Desai, Nikunj Tandel, Sandhya Choubey, Punam Barla, Deena Kanagaraj, Alex Eapen, Khageswar Pradhan, Ranvir Singh, Aarti Jain, Philip L Felgner, D Huw Davies, Jane M Carlton, Jyoti Das   +22 more
doaj   +1 more source

In vivo Susceptibility of Plasmodium vivax to Chloroquine in Southeastern Iran [PDF]

Iranian Journal of Parasitology, 2012
Background: Plasmodium vivax is the predominant species causes of malaria with about 90% total annual reported malaria in Iran. This study conducted to determine the susceptibility of Plasmodium vivax isolates to chloroquine in Sistan and Balochistan ...
A Heidari, H Keshavarz, S Shojaee, A Raeisi, S Dittrich   +4 more
doaj   +1 more source