Results 31 to 40 of about 50,182 (219)

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. [PDF]

, 2014
Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues.
Borboa, Rachel, Campo, Brice, Chatterjee, Arnab K, Chen, Zhong, Diagana, Thierry T, Gagaring, Kerstin, Glynne, Richard J, Klooster, Els J, Kocken, Clemens HM, Kuhen, Kelli, Leroy, Didier, Luty, Adrian, McNamara, Case W, Nagle, Advait, Plouffe, David M, Remarque, Edmond J, Roland, Jason, Sauerwein, Robert, Thomas, Alan W, van Amsterdam, Sandra M, van den Berg, Alexander, van Gemert, Geert-Jan, Voorberg-van der Wel, Annemarie, Winzeler, Elizabeth A, Yeung, Bryan KS, Zeeman, Anne-Marie   +25 more
core   +1 more source

Bradycardia in Severe <i>Plasmodium vivax</i> Malaria. [PDF]

J Glob Infect Dis
Agrawal PK, Panda SK, Yadav SS.
europepmc   +4 more sources

Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model [PDF]

, 2015
The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries.
Bassat, Quique, Betuela, Inoni, Brewster, Jessica, Felger, Ingrid, Hofmann, Natalie E., Karl, Stephan, Kinboro, Benson, Kiniboro, Benson, Li Wai Suen, Connie S. N., Lorry, Lina, Mueller, Ivo, Robinson, Leanne J., Samol, Lornah, Schofield, Louis, Siba, Peter M., Silkey, Mariabeth, Tarongka, Nandao, Waltmann, Andreea, Wampfler, Rahel, White, Michael T.   +19 more
core   +7 more sources

The detection of cryptic Plasmodium infection among villagers in Attapeu province, Lao PDR.

PLoS Neglected Tropical Diseases, 2017
BackgroundAlthough the malaria burden in the Lao PDR has gradually decreased, the elimination of malaria by 2030 presents many challenges. Microscopy and malaria rapid diagnostic tests (RDTs) are used to diagnose malaria in the Lao PDR; however, some ...
Moritoshi Iwagami, Sengdeuane Keomalaphet, Phonepadith Khattignavong, Pheovaly Soundala, Lavy Lorphachan, Emilie Matsumoto-Takahashi, Michel Strobel, Daniel Reinharz, Manisack Phommasansack, Bouasy Hongvanthong, Paul T Brey, Shigeyuki Kano   +11 more
doaj   +1 more source

Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?

Malaria Journal, 2022
Background The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding
Bárbara Aparecida Chaves, Denise Anete Madureira de Alvarenga, Matheus de Oliveira Costa Pereira, Marcelo Gordo, Emanuelle L. Da Silva, Edson Rodrigues Costa, Aline Souza de Menezes Medeiros, Igor José Martins Pedrosa, Daniela Brito, Maurício Teixeira Lima, Maria Paula Mourão, Wuelton M. Monteiro, Nikos Vasilakis, Cristiana Ferreira Alves de Brito, Gisely C. Melo, Marcus V. G. Lacerda   +15 more
doaj   +1 more source

An ultrasensitive reverse transcription polymerase chain reaction assay to detect asymptomatic low-density Plasmodium falciparum and Plasmodium vivax infections in small volume blood samples. [PDF]

, 2015
BackgroundHighly sensitive, scalable diagnostic methods are needed to guide malaria elimination interventions. While traditional microscopy and rapid diagnostic tests (RDTs) are suitable for the diagnosis of symptomatic malaria infection, more sensitive ...
Adams, Matthew, Han, Kay Thwe, Han, Zay Yar, Hlaing, Tin Maung, Huang, Fang, Johnson, Nicole Eddington, Joshi, Sudhaunshu N, Mbambo, Gillian, Mu, Amy Z, Nyunt, Myaing M, Oo, Khine Zaw, Plowe, Christopher V, Richards, Adam K, Roemmich, Shay M, Shrestha, Biraj, Strauss, Kathy A, Thura, Si   +16 more
core   +2 more sources

Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primates. [PDF]

PLoS ONE, 2014
Plasmodium vivax malaria causes significant morbidity and mortality worldwide, and only one drug is in clinical use that can kill the hypnozoites that cause P. vivax relapses. HIV and P.
Charlotte V Hobbs, Saurabh Dixit, Scott R Penzak, Tejram Sahu, Sachy Orr-Gonzalez, Lynn Lambert, Katie Zeleski, Jingyang Chen, Jillian Neal, William Borkowsky, Yimin Wu, Patrick E Duffy   +11 more
doaj   +1 more source

Vivax Malaria and the Potential Role of the Subtelomeric Multigene vir Superfamily

Microorganisms, 2022
Vivax malaria, caused by Plasmodium vivax, remains a public health concern in Central and Southeast Asia and South America, with more than two billion people at risk of infection. Compared to Plasmodium falciparum, P.
Youn-Kyoung Goo
doaj   +1 more source

Space-time variation of malaria incidence in Yunnan province, China [PDF]

, 2016
BACKGROUND Understanding spatio-temporal variation in malaria incidence provides a basis for effective disease control planning and monitoring. METHODS Monthly surveillance data between 1991 and 2006 for Plasmodium vivax and Plasmodium falciparum malaria
Barnett, Adrian G, Cheng, Zhang, Clements, Archie C A, Snow, Robert W, Zhou, Hom   +4 more
core   +1 more source

Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon

Brazilian Journal of Infectious Diseases, 2010
This report describes the development of hemolysis in eighteen glucose-6-phosphate dehydrogenase deficient patients treated for Plasmodium vivax malaria with chloroquine and primaquine.
Wilson M. Ramos Júnior, José F.J. Sardinha, Mônica R.F. Costa, Marli S. Santana, Maria G.C. Alecrim, Marcus V.G. Lacerda   +5 more
doaj   +1 more source