Results 41 to 50 of about 827,739 (268)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Testing phenol formaldehyde composite insulation material for conservation purposes

CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2018
This investigation related to the degradation of phenol formaldehyde based electrical insulation materials in close mechanical contact with CZ108 brass in a Post Office Type 36 time transmitter, an electromechanical clock.
Tabea Rude
doaj   +1 more source

Safety assessment of the process Resinas del Ecuador, based on the Starlinger iV+ technology, used to recycle post‐consumer PET into food contact materials

EFSA Journal, 2022
The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the recycling process Resinas del Ecuador (EU register number RECYC230), which uses the Starlinger iV+ technology.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Vincent Dudler, Maria Rosaria Milana, Constantine Papaspyrides, Maria de Fátima Tavares Poças, Alexandros Lioupis, Evgenia Lampi   +22 more
doaj   +1 more source

Plastic Pollution and Small Juvenile Marine Turtles: A Potential Evolutionary Trap

Frontiers in Marine Science, 2021
The ingestion of plastic by marine turtles is now reported for all species. Small juvenile turtles (including post-hatchling and oceanic juveniles) are thought to be most at risk, due to feeding preferences and overlap with areas of high plastic ...
Emily M. Duncan, Annette C. Broderick, Kay Critchell, Tamara S. Galloway, Mark Hamann, Colin J. Limpus, Penelope K. Lindeque, David Santillo, Anton D. Tucker, Scott Whiting, Erina J. Young, Brendan J. Godley   +11 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

First Report of Microplastic Ingestion and Bioaccumulation in Commercially Valuable European Anchovies (Engraulis encrasicolus, Linnaeus, 1758) from the Romanian Black Sea Coast

Journal of Marine Science and Engineering
Microplastics (
Andreea-Mădălina Ciucă, Elena Stoica, Lucica Barbeș   +2 more
doaj   +1 more source

Canaux anciens et puits récents : usages de l’eau d’irrigation, identité et territoire dans le Haouz (Maroc)

Développement Durable et Territoires, 2019
By associating an ethnography of contemporary practices and a diachronic approach, this article tries to show the co-construction over time of an irrigated soil and of a social group, in a locality in Marrakesh’s plain (Haouz).
Violaine Héritier-Salama
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source