Results 41 to 50 of about 14,949 (262)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A plastic load criterion for inelastic design by analysis
, 2006 The allowable plastic load in pressure vessel design by analysis is determined by applying a graphical construction to a characteristic load-deformation plot of the collapse behavior of the vessel.
Li, Hongjun +3 more
core +1 more source
Limited Plasticity of Prismatic Visuomotor Adaptation [PDF]
i-Perception, 2017 Movements toward an object displaced optically through prisms adapt quickly, a striking example for the plasticity of neuronal visuomotor programs. We investigated the degree and time course of this system’s plasticity. Participants performed goal-directed throwing or pointing movements with terminal feedback before, during, and after wearing prism ...
Karoline Spang +2 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Determination of Atterberg Limits using the vane shear test method
Bulletin of the Mineral Research and ExplorationAtterberg limits are important index parameters used to classify soils for various engineering applications. Engineering properties of soils are predicted through simple correlations with index properties and thereby the engineering behavior of soils are
Muhammed Beyhan +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Verification of the linear matching method for limit and shakedown analysis by comparison with experiments [PDF]
, 2013 The Linear Matching Method (LMM), a direct numerical method for determining shakedown and ratchet limits of components, has seen significant development in recent years. Previous verifications of these developments against cyclic nonlinear finite element
Tipping, David +5 more
core +1 more source
Bulletin of the Mineral Research and ExplorationThe main focus of the criticisms raised by O'Kelly and Soltani (2025) (hereafter referred to as discussers) to the authors' article in Bulletin of Mineral Research and Exploration (174, 1-10) is to examine the veracity of the strength-based equations ...
Muhammet Beyhan +3 more
doaj +1 more source
Plastic limit load of ellipsoidal pressure vessel head with nozzle under internal pressure loading
International Journal of Applied Mechanics and Engineering, 2013 A new method and numerical procedure for determining the plastic limit load in an ellipsoid-cylinder intersection using the elastic-plastic finite element analysis are presented. The proposed method is based on the maximum criterion of the rate of change
V.N. Skopinsky +2 more
doaj +1 more source
Reaching the Yield Point of a Glass During X-Ray Irradiation
Physical Review X, 2023 A solid loaded beyond the yield stress loses its elastic properties and becomes plastic. From a microscopic point of view, this limit corresponds to the condition where plastic regions become so densely packed that they give rise to system-spanning ...
Alessandro Martinelli +6 more
doaj +1 more source