Results 61 to 70 of about 317,747 (267)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Durability of wood plastic composites manufactured from recycled plastic

open access: yesHeliyon, 2018
The influence of accelerated weathering, xenon-arc light and freeze-thaw cycling on wood plastic composites extruded from a recycled plastic was studied.
Irina Turku, Timo Kärki, Ari Puurtinen
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Les polymères issus du végétal : matériaux à propriétés spécifiques pour des applications ciblées en industrie plastique [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2006
Features of plant-based polymers with special applications in plastic fi eld. The new interest of plastic fi eld with renewable resources results from a global environmental respect awareness and the fossil depletion problem.
Dubois P., Paquot M., Rabetafika HN.
doaj  

Effect of Mechanical and Geometrical Properties of Cement on Wellbore Stability Using 3-D Analysis

open access: yesWalailak Journal of Science and Technology, 2015
Especially in the long term, the role of the mechanical and geometrical properties of cement is very important to prevent cement failure and wellbore instability. Cement failure is the result of developed plastic strain.
Mohamad HEIDARIAN   +4 more
doaj   +1 more source

Elastic-plastic properties of mesoscale electrodeposited LIGA nickel alloy films: microscopy and mechanics. [PDF]

open access: yesJ Micromech Microeng, 2021
Liew LA   +7 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

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